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Dedifferentiation

Dedifferentiation (/ˌdiːdɪfəˌrɛnʃiˈeɪʃən/) is a transient process by which cells become less specialized and return to an earlier cell state within the same lineage. This suggests an increase in cell potency, meaning that, following dedifferentiation, a cell may possess the ability to re-differentiate into more cell types than it did before…

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Overview

History

Mechanisms

Plasticity

Vertebrates

Invertebrates

Other Terms Related to Dedifferentiation

Current Research and Future Implications

Advanced semantic analysis

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Map overview Semantic statistics

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Dedifferentiation

Nodes67
Edges66
Triples68
Avg. degree1.97
Density0.029851
Components1

How this topic connects Entity context

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Dedifferentiation

Top relations

related to history · 8
Dedifferentiation → Charles Manning Child, Epigenetic Landscape, Here, In, Just, References, Waddington, While Manning's
related to Involved pathways · 7
Dedifferentiation → BMP, MSX1, Notch, Reduced, Some, This, Wnt/β-catenin
related to Mice · 7
Dedifferentiation → After, In, Moreover, Ras, Ras/Raf/ERK, Schwann, These
related to Urodeles · 7
Dedifferentiation → Adult, Axolotls, It, Re-entry, Salamanders, These, This
related to Lancelet · 6
Dedifferentiation → Lancelets, PAX3, PAX7, The, This, Upon
related to Anaplasia · 5
Dedifferentiation → Anaplasia, However, In, Often, While
related to Observed markers of dedifferentiation · 5
Dedifferentiation → For, However, Matrix Metalloproteinases, MMP, Myogenin
related to Zebrafish · 4
Dedifferentiation → Danio, Specifically, The, Upon
related to Current Research and Future Implications · 3
Dedifferentiation → Currently, More, This
related to Invertebrates · 3
Dedifferentiation → It, Msx, This

Important terminology Word statistics

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Important terminology

cell cells regeneration expression differentiation pathway gene morphology metaplasia differentiated also less state transdifferentiation msx1 would new often increase induced

Entity relationships Subject–Predicate–Object triples

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SubjectPredicateObjectConfidenceSrc
Dedifferentiationrelated to AnaplasiaAnaplasia0.60section
Dedifferentiationrelated to AnaplasiaOften0.60section
Dedifferentiationrelated to AnaplasiaWhile0.60section
Dedifferentiationrelated to AnaplasiaHowever0.60section
Dedifferentiationrelated to AnaplasiaIn0.60section
Dedifferentiationrelated to Current Research and Future ImplicationsCurrently0.60section
Dedifferentiationrelated to Current Research and Future ImplicationsThis0.60section
Dedifferentiationrelated to Current Research and Future ImplicationsMore0.60section
Dedifferentiationrelated to historyReferences0.60section
Dedifferentiationrelated to historyCharles Manning Child0.60section
Dedifferentiationrelated to historyWhile Manning's0.60section
Dedifferentiationrelated to historyJust0.60section

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