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Cell potency is a cell's ability to differentiate into other cell types. The more cell types a cell can differentiate into, the greater its potency. Potency is also described as the gene activation potential within a cell, which like a continuum, begins with totipotency to designate a cell with the most differentiation potential, pluripotency…
Totipotency, Pluripotency & Multipotency
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cells cell differentiate stem pluripotency pluripotent ipscs also ability escs totipotency embryonic differentiation factors types potency teratoma research may germ
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Cell potency | is a | cell's ability to differentiate into other cell types | 0.90 | text |
| low replication rates | instance of | Setbacks | 0.80 | text |
| early senescence have also been encountered when making iPSCs | instance of | Setbacks | 0.80 | text |
| hindering their use as ESCs replacements.Somatic expression of combined transcription factors can directly induce other defined somatic cell fates | instance of | Setbacks | 0.80 | text |
| OCT4 | instance of | Core transcription factors | 0.80 | text |
| SOX2 | instance of | Core transcription factors | 0.80 | text |
| and NANOG form the central regulatory circuitry that sustains pluripotency by activating genes essential for self-renewal while repressing differentiation signals | instance of | Core transcription factors | 0.80 | text |
| B | instance of | can give rise to various blood cells | 0.80 | text |
| T cells | instance of | can give rise to various blood cells | 0.80 | text |
| however | instance of | can give rise to various blood cells | 0.80 | text |
| not to a different blood cell type like a red blood cell | instance of | can give rise to various blood cells | 0.80 | text |
| Cell potency | related to Totipotency | Totipotency | 0.60 | section |
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