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DCL4

DCL4 (Dicer-like 4) is a plant gene that encodes an enzyme involved in RNA silencing, a process by which cells regulate gene expression and defend against viruses. In flowering plants, DCL4 produces a specific class of small regulatory RNAs that help control development and protect against viral infection.

History, Evolutionary history & Function

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Evolutionary history

DCL3
1 related topics

Function

MiR390DCL2Oryza sativa
3 related topics

Overview

Ribonuclease IIISmall interfering RNAsTrans-acting siRNAsPhasiRNAsArabidopsis
8 related topics

Key facts & relationships

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Alt. symbols
AT5G20320
Chromosome
5: 6.86 - 6.87 Mb
Domains
InterPro
EC number
EC:3.1.26.3
Organism
Arabidopsis thaliana
Orthologs
OMA: entry

Topics to explore

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Overview

Function

Evolutionary history

Advanced semantic analysis

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Map overview Semantic statistics

DCL4

Nodes16
Edges15
Triples40
Avg. degree1.88
Density0.125
Components1

How this topic connects Entity context

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DCL4

Top relations

related to Function · 12
DCL4 → ARF, AUXIN RESPONSE FACTOR, Dicer-like, Following, Formation, In, RDR6, RNA, RNA-dependent RNA, RNAs, TAS, TAS3
related to history · 12
DCL4 → Comparative, DCL, DCL1, DCL3, DCL4-dependent TAS3, Dicer-like, Over, Phylogenetic, RNA-dependent RNA, RNAs, TAS3, This
is a · 3
DCL4 → core component of an ancient regulatory circuit linking small RNAs to developmental patterning, primary enzyme responsible for generating 21-nucleotide small interfering RNAs involved in post-transcriptional gene silencing, principal Dicer-like enzyme responsible for the phased processing of TAS3 transcripts into 21-nucleotide trans-acting siRNAs
Alt. symbols · 1
DCL4 → AT5G20320
Chromosome · 1
DCL4 → 5: 6.86 - 6.87 Mb
Domains · 1
DCL4 → InterPro
EC number · 1
DCL4 → EC:3.1.26.3
Organism · 1
DCL4 → Arabidopsis thaliana
Orthologs · 1
DCL4 → OMA: entry
PDB · 1
DCL4 → 2KOU

Important terminology Word statistics

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Important terminology

rna small sirnas plant rnas gene 21-nucleotide silencing dsrna phased plants arabidopsis dicer-like enzyme interfering pathways ta-sirnas functions trans-acting double-stranded

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DCL4Alt. symbolsAT5G203201.00infobox
DCL4Chromosome5: 6.86 - 6.87 Mb1.00infobox
DCL4DomainsInterPro1.00infobox
DCL4EC numberEC:3.1.26.31.00infobox
DCL4OrganismArabidopsis thaliana1.00infobox
DCL4OrthologsOMA: entry1.00infobox
DCL4PDB2KOU1.00infobox
DCL4Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
DCL4StructuresSwiss-model1.00infobox
DCL4SymbolDCL41.00infobox
DCL4UniProtP846341.00infobox
DCL4is aprincipal Dicer-like enzyme responsible for the phased processing of TAS3 transcripts into 21-nucleotide trans-acting siRNAs0.90text
DCL4is aprimary enzyme responsible for generating 21-nucleotide small interfering RNAs involved in post-transcriptional gene silencing0.90text
DCL4is acore component of an ancient regulatory circuit linking small RNAs to developmental patterning0.90text

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    Min side: 3
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