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Cytochrome c oxidase subunit III: Measurement & Standards

Cytochrome c oxidase subunit III (COX3) is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome c oxidase. It is also one of the three mitochondrial DNA (mtDNA) encoded subunits (MT-CO1, MT-CO2, MT-CO3) of respiratory complex IV. Variants of it have been associated with isolated myopathy, severe…

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Cytochrome c oxidase subunit III topic overview

The analysis highlights Measurement and Standards as prominent areas in the source structure around Cytochrome c oxidase subunit III.

Related topics
45
Source areas
6
Connected nodes
51
Extracted relationships
78
Related term clusters
16
Bridge connections
51

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 21 topics
Overview · 12 topics
Function · 4 topics
Interactions · 4 topics
Structure · 3 topics
Subfamilies · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

7.1.1.9
↗
Aliases
COX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III
Band
n/a
Bgee
gastric mucosa · skin of abdomen · skin of leg · left testis · right testis
BioGPS
n/a
Chr.
Mitochondrial DNA (human) · Mitochondrial DNA (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Subfamilies

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Cytochrome c oxidase subunit III connects Entity context

The extracted context around Cytochrome c oxidase subunit III shows recurring relationship patterns in the source. For example, Cytochrome c oxidase subunit III → amygdala, apex of heart, bone marrow, duodenum, epiblast, ganglionic eminence, gastric mucosa, hippocampus proper, jejunum, left testis, mucosa of transverse colon, olfactory zone of nasal mucosa, proximal tubule, quadriceps femoris muscle, right kidney, right testis, skin of abdomen, skin of leg, ventricular zone, zone of skin Another extracted example is Cytochrome c oxidase subunit III → aerobic dissimilation, aerobic electron transport chain, cytochrome-c oxidase activity, electron transfer activity, integral component of membrane, membrane, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial inner membrane, mitochondrial respiratory chain complex IV, mitochondrion, oxidoreduction-driven active transmembrane transporter activity, protein binding, proton transmembrane transport, respiratory chain complex IV, respiratory chain complex IV assembly, respiratory electron transport chain, transmembrane transport. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cytochrome c oxidase subunit III

Top relations

Bgee · 20
Cytochrome c oxidase subunit III → amygdala, apex of heart, bone marrow, duodenum, epiblast, ganglionic eminence, gastric mucosa, hippocampus proper, jejunum, left testis, mucosa of transverse colon, olfactory zone of nasal mucosa, proximal tubule, quadriceps femoris muscle, right kidney, right testis, skin of abdomen, skin of leg, ventricular zone, zone of skin
RNA expression pattern · 20
Cytochrome c oxidase subunit III → amygdala, apex of heart, bone marrow, duodenum, epiblast, ganglionic eminence, gastric mucosa, hippocampus proper, jejunum, left testis, mucosa of transverse colon, olfactory zone of nasal mucosa, proximal tubule, quadriceps femoris muscle, right kidney, right testis, skin of abdomen, skin of leg, ventricular zone, zone of skin
Gene ontology · 17
Cytochrome c oxidase subunit III → aerobic dissimilation, aerobic electron transport chain, cytochrome-c oxidase activity, electron transfer activity, integral component of membrane, membrane, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial inner membrane, mitochondrial respiratory chain complex IV, mitochondrion, oxidoreduction-driven active transmembrane transporter activity, protein binding, proton transmembrane transport, respiratory chain complex IV, respiratory chain complex IV assembly, respiratory electron transport chain, transmembrane transport
Chr. · 2
Cytochrome c oxidase subunit III → Mitochondrial DNA (human), Mitochondrial DNA (mouse)
End · 2
Cytochrome c oxidase subunit III → 9,390 bp, 9,990 bp
7.1.1.9 · 1
Cytochrome c oxidase subunit III → ↗
Aliases · 1
Cytochrome c oxidase subunit III → COX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III
Band · 1
Cytochrome c oxidase subunit III → n/a
BioGPS · 1
Cytochrome c oxidase subunit III → n/a
Databases · 1
Cytochrome c oxidase subunit III → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mitochondrial cytochrome oxidase complex iv dna bp gene subunit human cox3 respiratory chr band associated subunits deficiency iii myoglobinuria optic

Cytochrome c oxidase subunit III relationships Subject–Predicate–Object triples

TTTA extracted 78 structured relationships around Cytochrome c oxidase subunit III. Examples in this analysis include Cytochrome c oxidase subunit III → 7.1.1.9 → ↗ and Cytochrome c oxidase subunit III → Aliases → COX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Cytochrome c oxidase subunit III7.1.1.9↗1.00infobox
Cytochrome c oxidase subunit IIIAliasesCOX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III1.00infobox
Cytochrome c oxidase subunit IIIBandn/a1.00infobox
Cytochrome c oxidase subunit IIIBgeegastric mucosa1.00infobox
Cytochrome c oxidase subunit IIIBgeeskin of abdomen1.00infobox
Cytochrome c oxidase subunit IIIBgeeskin of leg1.00infobox
Cytochrome c oxidase subunit IIIBgeeleft testis1.00infobox
Cytochrome c oxidase subunit IIIBgeeright testis1.00infobox
Cytochrome c oxidase subunit IIIBgeemucosa of transverse colon1.00infobox
Cytochrome c oxidase subunit IIIBgeeapex of heart1.00infobox
Cytochrome c oxidase subunit IIIBgeeolfactory zone of nasal mucosa1.00infobox
Cytochrome c oxidase subunit IIIBgeeamygdala1.00infobox
Cytochrome c oxidase subunit IIIBgeehippocampus proper1.00infobox
Cytochrome c oxidase subunit IIIBgeequadriceps femoris muscle1.00infobox
Cytochrome c oxidase subunit IIIBgeeright kidney1.00infobox
Cytochrome c oxidase subunit IIIBgeeproximal tubule1.00infobox
Cytochrome c oxidase subunit IIIBgeeduodenum1.00infobox
Cytochrome c oxidase subunit IIIBgeeepiblast1.00infobox
Cytochrome c oxidase subunit IIIBgeeventricular zone1.00infobox
Cytochrome c oxidase subunit IIIBgeeganglionic eminence1.00infobox
Cytochrome c oxidase subunit IIIBgeezone of skin1.00infobox
Cytochrome c oxidase subunit IIIBgeejejunum1.00infobox
Cytochrome c oxidase subunit IIIBgeebone marrow1.00infobox
Cytochrome c oxidase subunit IIIBioGPSn/a1.00infobox
Cytochrome c oxidase subunit IIIChr.Mitochondrial DNA (human)1.00infobox
Cytochrome c oxidase subunit IIIChr.Mitochondrial DNA (mouse)1.00infobox
Cytochrome c oxidase subunit IIIDatabasesNCBI: entry; OMA: entry1.00infobox
Cytochrome c oxidase subunit IIIEnd9,990 bp1.00infobox
Cytochrome c oxidase subunit IIIEnd9,390 bp1.00infobox
Cytochrome c oxidase subunit IIIEnsemblENSG000001989381.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Cytochrome c oxidase subunit III bring nearby vocabulary together. In this analysis, examples include Oxidase, Subunit and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cytochrome c oxidase subunit III
    • Oxidase
    • Subunit
    • Gene
    • Iii
    • Mitochondrial
    • Cox3
    • Complex
    • Enzyme
    • Membrane
    • Respiratory
    • Iv
    • Encoded
  • cytochrome c oxidase subunit iii
    • Oxidase
    • Subunit
    • Enzyme
    • Gene
    • Iii
    • Mitochondrial
    • Cox3
    • Complex
    • Subunits
    • Membrane
    • Respiratory
    • Iv
  • enzyme
    • Gene
    • Iii
    • Oxidase
    • Subunit
    • Encoded
    • Hereditary
    • Leber
    • Lhon
    • Location
    • Mt-co3
    • Neuropathy
    • Chain
  • gene
    • Location
    • Bp
    • Chr
    • Human
    • Dna
    • Mt-co3
    • Subunit
    • Oxidase
    • Band
    • Protein
    • Iii
    • Iv
  • cytochrome c oxidase
    • Oxidase
    • Subunit
    • Gene
    • Iii
    • Mitochondrial
    • Cox3
    • Complex
    • Enzyme
    • Membrane
    • Respiratory
    • Iv
    • Encoded
  • mitochondrial dna
    • Bp
    • Chr
    • Human
    • Complex
    • Location
    • Iv
    • Band
    • Dna
    • Mitochondrial
    • Gene
    • Deficiency
    • Respiratory
  • respiratory complex iv
    • Iv
    • Deficiency
    • Chain
    • Mitochondrial
    • Hereditary
    • Isolated
    • Leber
    • Myopathy
    • Neuropathy
    • Severe
    • Myoglobinuria
    • Optic
  • inner mitochondrial membrane
    • Complex
    • Iv
    • Dna
    • Deficiency
    • Protein
    • Respiratory
    • Membrane
    • Mitochondrial
    • Bp
    • Chr
    • Human
    • Oxidase

Connections between topic areas Semantic bridges

For Cytochrome c oxidase subunit III, one of the stronger structural bridges in this analysis connects Cytochrome c oxidase subunit III with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Cytochrome c oxidase subunit III — Clinical significance · splits 30 ⟂ 22
Cytochrome c oxidase subunit III — Overview · splits 39 ⟂ 13
Cytochrome c oxidase subunit III — Function · splits 47 ⟂ 5
Cytochrome c oxidase subunit III — Interactions · splits 47 ⟂ 5
Cytochrome c oxidase subunit III — Structure · splits 48 ⟂ 4

Map overview Semantic statistics

Cytochrome c oxidase subunit III

Nodes52
Edges51
Triples78
Avg. degree1.96
Density0.038462
Components1

Source & methodology

TTTA analyzes the structure around Cytochrome c oxidase subunit III to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cytochrome c oxidase subunit III · EN edition · Analysis: TopicsToTalkAbout

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