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COX10: Measurement, Clinical Significance & Structure

Protoheme IX farnesyltransferase, mitochondrial is an enzyme that in humans is encoded by the COX10 gene. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by…

Language: English [EN]
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COX10 topic overview

The analysis highlights Measurement, Clinical Significance and Structure as prominent areas in the source structure around COX10.

Related topics
56
Source areas
5
Connected nodes
61
Extracted relationships
104
Concept neighborhoods
25
Bridge connections
61

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 25 topics
Clinical Significance · 13 topics
Structure · 11 topics
Function · 5 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.5.1.141
Aliases
COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor, cytochrome c oxidase assembly factor heme A:farnesyltransferase MC4DN3
Band
17p12 · 11|11 B3
Bgee
tibialis anterior muscle · thoracic diaphragm · myocardium of left ventricle · deltoid muscle · gastrocnemius muscle
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical Significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How COX10 connects Entity context

The extracted context around COX10 shows recurring relationship patterns in the source. For example, COX10 → aerobic dissimilation, cellular respiration, cytochrome complex, cytochrome complex assembly, cytochrome-c oxidase activity, cytosol, farnesyltranstransferase activity, heme A biosynthetic process, heme biosynthetic process, heme O biosynthetic process, integral component of membrane, membrane, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial fission, mitochondrial inner membrane, mitochondrial membranes, mitochondrion, mitochondrion organization, nucleolus, protoheme IX farnesyltransferase activity Another extracted example is COX10 → biceps brachii, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, muscle of thigh, myocardium of left ventricle, myocardium of ventricle, otic vesicle, primary oocyte, secondary oocyte, skeletal muscle tissue, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

COX10

Top relations

Gene ontology · 24
COX10 → aerobic dissimilation, cellular respiration, cytochrome complex, cytochrome complex assembly, cytochrome-c oxidase activity, cytosol, farnesyltranstransferase activity, heme A biosynthetic process, heme biosynthetic process, heme O biosynthetic process, integral component of membrane, membrane, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial fission, mitochondrial inner membrane, mitochondrial membranes, mitochondrion, mitochondrion organization, nucleolus, protoheme IX farnesyltransferase activity
Bgee · 18
COX10 → biceps brachii, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, muscle of thigh, myocardium of left ventricle, myocardium of ventricle, otic vesicle, primary oocyte, secondary oocyte, skeletal muscle tissue, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, zygote
RNA expression pattern · 18
COX10 → biceps brachii, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, muscle of thigh, myocardium of left ventricle, myocardium of ventricle, otic vesicle, primary oocyte, secondary oocyte, skeletal muscle tissue, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, zygote
related to Clinical Significance · 9
COX10 → Charcot-Marie-Tooth, CMT1A, COX, French Canadian, HNPP, In, Leigh, Leigh Syndrome, Mutations
related to Structure · 6
COX10 → II/III, The, The COX10, There, This, VI/VII
related to Function · 4
COX10 → C2, COX, It, The
Band · 2
COX10 → 11|11 B3, 17p12
Chr. · 2
COX10 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
COX10 → 14,231,736 bp, 63,970,294 bp
related to External links · 2
COX10 → Human COX10, UCSC Genome Browser

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene mitochondrial bp human farnesyltransferase chr band heme chromosome 17 cytochrome oxidase protein complex cox assembly location component electron function

COX10 relationships Subject–Predicate–Object triples

TTTA extracted 104 structured relationships around COX10. Examples in this analysis include COX10 → 2.5.1.141 → ↗ and COX10 → Aliases → COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor, cytochrome c oxidase assembly factor heme A:farnesyltransferase MC4DN3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
COX102.5.1.1411.00infobox
COX10AliasesCOX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor, cytochrome c oxidase assembly factor heme A:farnesyltransferase MC4DN31.00infobox
COX10Band17p121.00infobox
COX10Band11|11 B31.00infobox
COX10Bgeetibialis anterior muscle1.00infobox
COX10Bgeethoracic diaphragm1.00infobox
COX10Bgeemyocardium of left ventricle1.00infobox
COX10Bgeedeltoid muscle1.00infobox
COX10Bgeegastrocnemius muscle1.00infobox
COX10Bgeetriceps brachii muscle1.00infobox
COX10Bgeevastus lateralis muscle1.00infobox
COX10Bgeemuscle of thigh1.00infobox
COX10Bgeesecondary oocyte1.00infobox
COX10Bgeebiceps brachii1.00infobox
COX10Bgeezygote1.00infobox
COX10Bgeeinterventricular septum1.00infobox
COX10Bgeeotic vesicle1.00infobox
COX10Bgeeprimary oocyte1.00infobox
COX10Bgeemyocardium of ventricle1.00infobox
COX10Bgeeskeletal muscle tissue1.00infobox
COX10Bgeeextraocular muscle1.00infobox
COX10Bgeedigastric muscle1.00infobox
COX10BioGPSMore reference expression data1.00infobox
COX10Chr.Chromosome 17 (human)1.00infobox
COX10Chr.Chromosome 11 (mouse)1.00infobox
COX10DatabasesNCBI: entry; OMA: entry1.00infobox
COX10End14,231,736 bp1.00infobox
COX10End63,970,294 bp1.00infobox
COX10EnsemblENSG000000066951.00infobox
COX10Entrez13521.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around COX10 bring nearby vocabulary together. In this analysis, examples include Farnesyltransferase, Gene and Heme. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • COX10
    • Farnesyltransferase
    • Gene
    • Heme
    • Assembly
    • Location
    • Human
    • Enzyme
    • Expression
    • Ix
    • Mitochondrial
    • Encoded
    • Function
  • cox10
    • Farnesyltransferase
    • Gene
    • Heme
    • Assembly
    • Location
    • Human
    • Enzyme
    • Expression
    • Ix
    • Mitochondrial
    • Encoded
    • Function
  • gene
    • Location
    • Human
    • Chromosome
    • Cytochrome
    • Oxidase
    • Bp
    • Chr
    • Heme
    • Cmt1a
    • Deletion
    • Expression
    • Ix
  • cytochrome c oxidase
    • Oxidase
    • Chain
    • Oxygen
    • Respiratory
    • Component
    • Electron
    • Function
    • Assembly
    • Chromosome
    • Farnesyltransferase
    • Location
    • Bp
  • mitochondrial respiratory chain
    • Oxygen
    • Respiratory
    • Component
    • Electron
    • Cytochrome
    • Oxidase
    • Protein
    • Encoded
    • Inner
    • Membrane
    • Catalyzes
    • Expression
  • electron transfer
    • Electron
    • Oxygen
    • Respiratory
    • Transfer
    • Complex
    • Function
    • Assembly
    • Oxidase
    • Catalyzes
    • Chain
    • Subunits
    • Component
  • cytochrome c
    • Oxidase
    • Chain
    • Oxygen
    • Respiratory
    • Component
    • Electron
    • Function
    • Assembly
    • Chromosome
    • Farnesyltransferase
    • Location
    • Bp
  • complex
    • Subunits
    • Component
    • Electron
    • Function
    • Assembly
    • Expression
    • Ix
    • Mitochondrial
    • Mouse
    • Nuclear
    • Oxygen
    • Respiratory

Connections between topic areas Semantic bridges

For COX10, one of the stronger structural bridges in this analysis connects COX10 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
COX10Overview · splits 36 ⟂ 26
COX10Clinical Significance · splits 48 ⟂ 14
COX10Structure · splits 50 ⟂ 12
COX10Function · splits 56 ⟂ 6
COX10Interactions · splits 59 ⟂ 3

Map overview Semantic statistics

COX10

Nodes62
Edges61
Triples104
Avg. degree1.97
Density0.032258
Components1

Source & methodology

TTTA analyzes the structure around COX10 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Clinical Significance & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — COX10 · EN edition · Analysis: TopicsToTalkAbout

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