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Cortactin (from "cortical actin binding protein") is a monomeric protein located in the cytoplasm of cells that can be activated by external stimuli to promote polymerization and rearrangement of the actin cytoskeleton, especially the actin cortex around the cellular periphery. It is present in all cell types. When activated, it will recruit Arp2/3…
The analysis highlights Geography and Regions as prominent areas in the source structure around Cortactin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Cortactin shows recurring relationship patterns in the source. For example, Cortactin → actin cytoskeleton reorganization, actin filament, actin filament polymerization, cadherin binding, cell cortex, cell junction, cell motility, cell projection, clathrin-coated pit, cortical cytoskeleton, cytoplasm, cytoskeleton, cytosol, dendrite, dendritic spine, dendritic spine maintenance, endocytosis, extracellular exosome, focal adhesion, focal adhesion assembly Another extracted example is Cortactin → body of uterus, calvaria, canal of the cervix, cumulus cell, endothelial cell of lymphatic vessel, epithelium of stomach, gastric mucosa, gastrula, left adrenal cortex, left ovary, medullary collecting duct, myometrium, Paneth cell, renal corpuscle, right adrenal cortex, right ovary, right uterine tube, stromal cell of endometrium, tail of embryo, transitional epithelium of urinary bladder. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
actin cell arp2 bp complex activated polymerization chr gene human band endocytosis chromosome 11 protein binding location kinases cortex nucleation
TTTA extracted 143 structured relationships around Cortactin. Examples in this analysis include Cortactin → Aliases → CTTN, EMS1, cortactin and Cortactin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X69, 2D1X. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Cortactin | Aliases | CTTN, EMS1, cortactin | 1.00 | infobox |
| Cortactin | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X69, 2D1X | 1.00 | infobox |
| Cortactin | Band | 11q13.3 | 1.00 | infobox |
| Cortactin | Band | 7|7 F5 | 1.00 | infobox |
| Cortactin | Bgee | stromal cell of endometrium | 1.00 | infobox |
| Cortactin | Bgee | body of uterus | 1.00 | infobox |
| Cortactin | Bgee | left ovary | 1.00 | infobox |
| Cortactin | Bgee | right ovary | 1.00 | infobox |
| Cortactin | Bgee | right adrenal cortex | 1.00 | infobox |
| Cortactin | Bgee | myometrium | 1.00 | infobox |
| Cortactin | Bgee | gastric mucosa | 1.00 | infobox |
| Cortactin | Bgee | right uterine tube | 1.00 | infobox |
| Cortactin | Bgee | canal of the cervix | 1.00 | infobox |
| Cortactin | Bgee | left adrenal cortex | 1.00 | infobox |
| Cortactin | Bgee | medullary collecting duct | 1.00 | infobox |
| Cortactin | Bgee | transitional epithelium of urinary bladder | 1.00 | infobox |
| Cortactin | Bgee | gastrula | 1.00 | infobox |
| Cortactin | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| Cortactin | Bgee | cumulus cell | 1.00 | infobox |
| Cortactin | Bgee | calvaria | 1.00 | infobox |
| Cortactin | Bgee | Paneth cell | 1.00 | infobox |
| Cortactin | Bgee | epithelium of stomach | 1.00 | infobox |
| Cortactin | Bgee | renal corpuscle | 1.00 | infobox |
| Cortactin | Bgee | tail of embryo | 1.00 | infobox |
| Cortactin | BioGPS | More reference expression data | 1.00 | infobox |
| Cortactin | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| Cortactin | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| Cortactin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Cortactin | End | 70,436,584 bp | 1.00 | infobox |
| Cortactin | End | 144,024,746 bp | 1.00 | infobox |
The concept neighborhoods around Cortactin bring nearby vocabulary together. In this analysis, examples include Actin, Cell and Polymerization. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Cortactin, one of the stronger structural bridges in this analysis connects Cortactin with Activation and binding. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Cortactin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Geography & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Cortactin · EN edition · Analysis: TopicsToTalkAbout