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Copanlisib: History, Community & Culture

Copanlisib, sold under the brand name Aliqopa, is a medication used for the treatment of adults experiencing relapsed follicular lymphoma who have received at least two prior systemic therapies.

Language: English [EN]
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Copanlisib topic overview

The analysis highlights History, Community and Culture as prominent areas in the source structure around Copanlisib.

Related topics
35
Source areas
5
Connected nodes
40
Extracted relationships
60
Concept neighborhoods
20
Bridge connections
40

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 11 topics
History · 11 topics
Society and culture · 7 topics
Mechanism of action · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01EM02 (WHO)
CAS Number
1032568-63-0
ChEBI
CHEBI:173077
ChEMBL
ChEMBL3218576

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Adverse effects

Mechanism of action

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Copanlisib connects Entity context

The extracted context around Copanlisib shows recurring relationship patterns in the source. For example, Copanlisib → B-cell, Consequently, HER2, HER2-inhibitors, HER2-positive, Hodgkin, III, In, NHL, Phase II, R-B, R-CHOP, This, Two Another extracted example is Copanlisib → Drug Administration, FDA, February, Food, For, Further, In September, May, The New. Use these groups to spot repeated connection types before inspecting the individual relationships.

Copanlisib

Top relations

related to Clinical trials · 14
Copanlisib → B-cell, Consequently, HER2, HER2-inhibitors, HER2-positive, Hodgkin, III, In, NHL, Phase II, R-B, R-CHOP, This, Two
related to Legal status · 9
Copanlisib → Drug Administration, FDA, February, Food, For, Further, In September, May, The New
related to Mechanism of action · 5
Copanlisib → B-cells, It, PI3K, PI3K-α, PI3K-δ
has effect · 3
Copanlisib → Data, FDA Drug Trial Snapshot, The
related to history · 3
Copanlisib → Efficacy, II, To
License data · 2
Copanlisib → US DailyMed: Copanlisib, US FDA: 209936
3D model (JSmol) · 1
Copanlisib → Interactive image
AHFS/Drugs.com · 1
Copanlisib → Monograph
ATC code · 1
Copanlisib → L01EM02 (WHO)
CAS Number · 1
Copanlisib → 1032568-63-0

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

lymphoma follicular drug treatment clinical trials status phase adults relapsed two fda effects data name aliqopa us legal trial cancer

Copanlisib relationships Subject–Predicate–Object triples

TTTA extracted 60 structured relationships around Copanlisib. Examples in this analysis include Copanlisib → 3D model (JSmol) → Interactive image and Copanlisib → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Copanlisib3D model (JSmol)Interactive image1.00infobox
CopanlisibAHFS/Drugs.comMonograph1.00infobox
CopanlisibATC codeL01EM02 (WHO)1.00infobox
CopanlisibCAS Number1032568-63-01.00infobox
CopanlisibChEBICHEBI:1730771.00infobox
CopanlisibChEMBLChEMBL32185761.00infobox
CopanlisibChemSpider250696831.00infobox
CopanlisibCompTox Dashboard (EPA)DTXSID001457281.00infobox
CopanlisibDrug classPI3-Kinase inhibitor1.00infobox
CopanlisibDrugBankDB124831.00infobox
CopanlisibElimination half-life39.1 hours (range: 14.6 to 82.4)1.00infobox
CopanlisibExcretionFeces (64%), Urine (22%); 14% were not recovered1.00infobox
CopanlisibFormulaC23H28N8O41.00infobox
CopanlisibKEGGD108671.00infobox
CopanlisibLegal statusUS: ℞-only1.00infobox
CopanlisibLicense dataUS DailyMed: Copanlisib1.00infobox
CopanlisibLicense dataUS FDA: 2099361.00infobox
CopanlisibMedlinePlusa6170441.00infobox
CopanlisibMetabolismCYP3A4/5 (≈90%), CYP1A1 (≈10%)1.00infobox
CopanlisibMolar mass480.529 g·mol−11.00infobox
CopanlisibOther namesBAY 80-69461.00infobox
CopanlisibProtein binding84.2%1.00infobox
CopanlisibPubChem CID249890441.00infobox
CopanlisibRoutes of administrationIntravenous1.00infobox
CopanlisibTrade namesAliqopa1.00infobox
CopanlisibUNIIWI6V529FZ91.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Copanlisib bring nearby vocabulary together. In this analysis, examples include Lymphoma, Drug and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Copanlisib
    • Lymphoma
    • Drug
    • Effects
    • Trial
    • Phase
    • Follicular
    • Administration
    • Aliqopa
    • Data
    • Efficacy
    • Fda
    • Hyperglycemia
  • copanlisib
    • Lymphoma
    • Drug
    • Effects
    • Trial
    • Phase
    • Follicular
    • Administration
    • Aliqopa
    • Data
    • Efficacy
    • Fda
    • Hyperglycemia
  • follicular lymphoma
    • Lymphoma
    • Treatment
    • Least
    • Prior
    • Received
    • Relapsed
    • Systemic
    • Therapies
    • Phase
    • Two
    • Drug
    • Trial
  • clinical trial
    • Trials
    • Efficacy
    • Phase
    • Trial
    • Legal
    • Rituximab
    • Us
    • Administration
    • Data
    • Fda
    • Inhibitor
    • Name
  • diffuse large b-cell lymphoma
    • Treatment
    • Relapsed
    • Phase
    • Drug
    • Least
    • Prior
    • Received
    • Systemic
    • Therapies
    • Trial
    • Two
    • Clinical
  • non-hodgkin lymphoma
    • Treatment
    • Relapsed
    • Phase
    • Drug
    • Least
    • Prior
    • Received
    • Systemic
    • Therapies
    • Trial
    • Two
    • Clinical
  • marginal zone lymphoma
    • Treatment
    • Relapsed
    • Phase
    • Drug
    • Least
    • Prior
    • Received
    • Systemic
    • Therapies
    • Trial
    • Two
    • Clinical
  • food and drug administration
    • Fda
    • Legal
    • Drug
    • Safety
    • Status
    • Aliqopa
    • Data
    • Efficacy
    • Inhibitor
    • Name
    • Us
    • Lymphoma

Connections between topic areas Semantic bridges

For Copanlisib, one of the stronger structural bridges in this analysis connects Copanlisib with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CopanlisibAdverse effects · splits 29 ⟂ 12
CopanlisibHistory · splits 29 ⟂ 12
CopanlisibSociety and culture · splits 33 ⟂ 8
CopanlisibMechanism of action · splits 36 ⟂ 5
CopanlisibOverview · splits 38 ⟂ 3

Map overview Semantic statistics

Copanlisib

Nodes41
Edges40
Triples60
Avg. degree1.95
Density0.04878
Components1

Source & methodology

TTTA analyzes the structure around Copanlisib to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community & Culture, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Copanlisib · EN edition · Analysis: TopicsToTalkAbout

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