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Complement component 5

Complement component 5 is a protein that in humans is encoded by the C5 gene.

Applications, Therapeutic applications & Function

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Explore the main themes, entities and connections around Complement component 5. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Therapeutic applications

1 related topics

Function

4 related topics

Clinical significance

2 related topics

Overview

7 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
C5, C5D, C5a, C5b, CPAMD4, ECLZB, complement component 5, complement C5
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CFA, 1KJS, 1XWE, 3CU7, 3HQA, 3HQB, 3KLS, 3KM9, 3PRX, 3PVM, 4A5W, 4E0S, 4P39, 4UU9, 5I5K, 5HCE, 5HCC, 5HCD
Band
9q33.2 · 2 B|2 23.22 cM
Bgee
right lobe of liver · oocyte · body of pancreas · secondary oocyte · Achilles tendon
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)

Topics to explore

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Overview

Function

Clinical significance

Therapeutic applications

Advanced semantic analysis

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Map overview Semantic statistics

Complement component 5

Nodes19
Edges18
Triples99
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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Complement component 5

Top relations

Gene ontology · 26
Complement component 5 → cell chemotaxis, cell surface receptor signaling pathway, chemokine activity, chemotaxis, complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, endopeptidase inhibitor activity, extracellular exosome, extracellular region, extracellular space, G protein-coupled receptor signaling pathway, immune system process, in utero embryonic development, inflammatory response, innate immune response, membrane attack complex, negative regulation of endopeptidase activity, negative regulation of macrophage chemotaxis
Bgee · 20
Complement component 5 → Achilles tendon, body of pancreas, Descending thoracic aorta, embryo, fetal liver hematopoietic progenitor cell, gallbladder, gonad, granulocyte, human fetus, left lobe of liver, left lung, left lung lobe, neural groove, oocyte, right lobe of liver, right lung lobe, secondary oocyte, testicle, tibial nerve, ventricular zone
RNA expression pattern · 20
Complement component 5 → Achilles tendon, body of pancreas, Descending thoracic aorta, embryo, fetal liver hematopoietic progenitor cell, gallbladder, gonad, granulocyte, human fetus, left lobe of liver, left lung, left lung lobe, neural groove, oocyte, right lobe of liver, right lung lobe, secondary oocyte, testicle, tibial nerve, ventricular zone
related to Function · 7
Complement component 5 → An, C5-convertase, C5a, C6, Complement, The C5b, This
Band · 2
Complement component 5 → 2 B|2 23.22 cM, 9q33.2
Chr. · 2
Complement component 5 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
Complement component 5 → 121,075,195 bp, 34,951,450 bp
related to Clinical significance · 2
Complement component 5 → Defects, Mutations
Aliases · 1
Complement component 5 → C5, C5D, C5a, C5b, CPAMD4, ECLZB, complement component 5, complement C5
Available structures · 1
Complement component 5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CFA, 1KJS, 1XWE, 3CU7, 3HQA, 3HQB, 3KLS, 3KM9, 3PRX, 3PVM, 4A5W, 4E0S, 4P39, 4UU9, 5I5K, 5HCE, 5HCC, 5HCD

Important terminology Word statistics

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Important terminology

complement component bp gene c5b chr human band c5 chromosome c5a system protein membrane attack complex location chemotaxis mouse function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Complement component 5AliasesC5, C5D, C5a, C5b, CPAMD4, ECLZB, complement component 5, complement C51.00infobox
Complement component 5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CFA, 1KJS, 1XWE, 3CU7, 3HQA, 3HQB, 3KLS, 3KM9, 3PRX, 3PVM, 4A5W, 4E0S, 4P39, 4UU9, 5I5K, 5HCE, 5HCC, 5HCD1.00infobox
Complement component 5Band9q33.21.00infobox
Complement component 5Band2 B|2 23.22 cM1.00infobox
Complement component 5Bgeeright lobe of liver1.00infobox
Complement component 5Bgeeoocyte1.00infobox
Complement component 5Bgeebody of pancreas1.00infobox
Complement component 5Bgeesecondary oocyte1.00infobox
Complement component 5BgeeAchilles tendon1.00infobox
Complement component 5Bgeegonad1.00infobox
Complement component 5Bgeetibial nerve1.00infobox
Complement component 5Bgeetesticle1.00infobox
Complement component 5BgeeDescending thoracic aorta1.00infobox
Complement component 5Bgeeventricular zone1.00infobox
Complement component 5Bgeeleft lobe of liver1.00infobox
Complement component 5Bgeeright lung lobe1.00infobox
Complement component 5Bgeeleft lung1.00infobox
Complement component 5Bgeeleft lung lobe1.00infobox
Complement component 5Bgeegallbladder1.00infobox
Complement component 5Bgeegranulocyte1.00infobox
Complement component 5Bgeefetal liver hematopoietic progenitor cell1.00infobox
Complement component 5Bgeehuman fetus1.00infobox
Complement component 5Bgeeneural groove1.00infobox
Complement component 5Bgeeembryo1.00infobox
Complement component 5BioGPSMore reference expression data1.00infobox
Complement component 5Chr.Chromosome 9 (human)1.00infobox
Complement component 5Chr.Chromosome 2 (mouse)1.00infobox
Complement component 5DatabasesNCBI: entry; OMA: entry1.00infobox
Complement component 5End121,075,195 bp1.00infobox
Complement component 5End34,951,450 bp1.00infobox

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