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CLEC6A: Functions, Signaling & Structure

Dectin-2 or C-type lectin domain containing 6A is a protein that in humans is encoded by the CLEC6A gene. Dectin-2 is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded protein is a type II transmembrane protein with an extracellular carbohydrate recognition domain. It functions as a pattern recognition receptor…

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CLEC6A topic overview

The analysis highlights Functions, Signaling and Structure as prominent areas in the source structure around CLEC6A.

Related topics
37
Source areas
4
Connected nodes
41
Extracted relationships
78
Concept neighborhoods
12
Bridge connections
41

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Functions · 15 topics
Signaling · 14 topics
Overview · 6 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CLEC6A, CLEC4N, CLECSF10, C-type lectin domain family 6 member A, dectin-2, C-type lectin domain containing 6A, hDECTIN-2
Band
12p13.31 · 6 F2|6 58.3 cM
Bgee
testicle · monocyte · appendix · granulocyte · blood
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Signaling

Functions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CLEC6A connects Entity context

The extracted context around CLEC6A shows recurring relationship patterns in the source. For example, CLEC6A → appendix, blood, calvaria, carotid body, endometrium, gallbladder, gonad, granulocyte, jejunum, lymph node, mesenteric lymph nodes, monocyte, right lung lobe, smooth muscle tissue, spermatid, spleen, stroma of bone marrow, testicle, thymus Another extracted example is CLEC6A → adaptive immune response, calcium ion binding, carbohydrate binding, defense response to fungus, immune system process, innate immune response, integral component of membrane, mannose binding, membrane, metal ion binding, plasma membrane, positive regulation of I-kappaB kinase/NF-kappaB signaling, stimulatory C-type lectin receptor signaling pathway. Use these groups to spot repeated connection types before inspecting the individual relationships.

CLEC6A

Top relations

Bgee · 19
CLEC6A → appendix, blood, calvaria, carotid body, endometrium, gallbladder, gonad, granulocyte, jejunum, lymph node, mesenteric lymph nodes, monocyte, right lung lobe, smooth muscle tissue, spermatid, spleen, stroma of bone marrow, testicle, thymus
RNA expression pattern · 19
CLEC6A → appendix, blood, calvaria, carotid body, endometrium, gallbladder, gonad, granulocyte, jejunum, lymph node, mesenteric lymph nodes, monocyte, right lung lobe, smooth muscle tissue, spermatid, spleen, stroma of bone marrow, testicle, thymus
Gene ontology · 13
CLEC6A → adaptive immune response, calcium ion binding, carbohydrate binding, defense response to fungus, immune system process, innate immune response, integral component of membrane, mannose binding, membrane, metal ion binding, plasma membrane, positive regulation of I-kappaB kinase/NF-kappaB signaling, stimulatory C-type lectin receptor signaling pathway
Band · 2
CLEC6A → 12p13.31, 6 F2|6 58.3 cM
Chr. · 2
CLEC6A → Chromosome 12 (human), Chromosome 6 (mouse)
End · 2
CLEC6A → 123,223,980 bp, 8,478,330 bp
Aliases · 1
CLEC6A → CLEC6A, CLEC4N, CLECSF10, C-type lectin domain family 6 member A, dectin-2, C-type lectin domain containing 6A, hDECTIN-2
BioGPS · 1
CLEC6A → n/a
Databases · 1
CLEC6A → NCBI: entry; OMA: entry
Ensembl · 1
CLEC6A → ENSG00000205846

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dectin-2 domain c-type lectin response human also bp gene signaling chromosome 12 receptor immune protein chr band albicans recognition cytokines

CLEC6A relationships Subject–Predicate–Object triples

TTTA extracted 78 structured relationships around CLEC6A. Examples in this analysis include CLEC6A → Aliases → CLEC6A, CLEC4N, CLECSF10, C-type lectin domain family 6 member A, dectin-2, C-type lectin domain containing 6A, hDECTIN-2 and CLEC6A → Band → 12p13.31. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CLEC6AAliasesCLEC6A, CLEC4N, CLECSF10, C-type lectin domain family 6 member A, dectin-2, C-type lectin domain containing 6A, hDECTIN-21.00infobox
CLEC6ABand12p13.311.00infobox
CLEC6ABand6 F2|6 58.3 cM1.00infobox
CLEC6ABgeetesticle1.00infobox
CLEC6ABgeemonocyte1.00infobox
CLEC6ABgeeappendix1.00infobox
CLEC6ABgeegranulocyte1.00infobox
CLEC6ABgeeblood1.00infobox
CLEC6ABgeelymph node1.00infobox
CLEC6ABgeegonad1.00infobox
CLEC6ABgeesmooth muscle tissue1.00infobox
CLEC6ABgeegallbladder1.00infobox
CLEC6ABgeeendometrium1.00infobox
CLEC6ABgeestroma of bone marrow1.00infobox
CLEC6ABgeespleen1.00infobox
CLEC6ABgeecalvaria1.00infobox
CLEC6ABgeemesenteric lymph nodes1.00infobox
CLEC6ABgeeright lung lobe1.00infobox
CLEC6ABgeethymus1.00infobox
CLEC6ABgeecarotid body1.00infobox
CLEC6ABgeespermatid1.00infobox
CLEC6ABgeejejunum1.00infobox
CLEC6ABioGPSn/a1.00infobox
CLEC6AChr.Chromosome 12 (human)1.00infobox
CLEC6AChr.Chromosome 6 (mouse)1.00infobox
CLEC6ADatabasesNCBI: entry; OMA: entry1.00infobox
CLEC6AEnd8,478,330 bp1.00infobox
CLEC6AEnd123,223,980 bp1.00infobox
CLEC6AEnsemblENSG000002058461.00infobox
CLEC6AEntrez939781.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CLEC6A bring nearby vocabulary together. In this analysis, examples include Gene, Encoded and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CLEC6A
    • Gene
    • Encoded
    • Location
    • Lectin
    • Protein
    • Bp
    • Chr
    • Chromosome
    • Human
    • Signaling
    • Domain
    • Family
  • clec6a
    • Gene
    • Encoded
    • Location
    • Lectin
    • Protein
    • Bp
    • Chr
    • Chromosome
    • Human
    • Signaling
    • Domain
    • Family
  • c-type lectin
    • Lectin
    • Clec6a
    • Family
    • Member
    • Domain
    • Gene
    • Encoded
    • Ii
    • Location
    • Pattern
    • Dectin-2
    • Carbohydrate
  • innate immune response
    • Pattern
    • Receptor
    • Response
    • Induction
    • Albicans
    • Immune
    • Innate
    • Cytokines
    • Defense
    • Signaling
    • Recognition
    • Location
  • signaling
    • Clec6a
    • Innate
    • Location
    • Defense
    • Expression
    • Activation
    • Bp
    • Chr
    • Chromosome
    • Gene
    • Human
    • Production
  • pattern recognition receptor
    • Immune
    • Innate
    • Receptor
    • Response
    • Recognition
    • Binding
    • Defense
    • Induction
    • Albicans
    • Family
    • Location
    • Member
  • functions
    • Family
    • Innate
    • Location
    • Member
    • Pattern
    • Important
    • Bp
    • Chr
    • Chromosome
    • Gene
    • Human
    • Recognition
  • fc receptor γ
    • Response
    • Binding
    • Defense
    • Induction
    • Recognition
    • Albicans
    • Family
    • Location
    • Member
    • Mouse
    • Band
    • Expression

Connections between topic areas Semantic bridges

For CLEC6A, one of the stronger structural bridges in this analysis connects CLEC6A with Functions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CLEC6AFunctions · splits 26 ⟂ 16
CLEC6ASignaling · splits 27 ⟂ 15
CLEC6AOverview · splits 35 ⟂ 7
CLEC6AStructure · splits 39 ⟂ 3

Map overview Semantic statistics

CLEC6A

Nodes42
Edges41
Triples78
Avg. degree1.95
Density0.047619
Components1

Source & methodology

TTTA analyzes the structure around CLEC6A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Functions, Signaling & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CLEC6A · EN edition · Analysis: TopicsToTalkAbout

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