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CD30

TNF receptor superfamily member 8, also known as CD30, is a cell membrane protein of the tumor necrosis factor receptor family encoded by the TNFRSF8 gene. It is a tumor marker for Hodgkin lymphoma and anaplastic large cell lymphoma.

Function, Clinical significance & Cancer treatment

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Function

6 related topics

Clinical significance

6 related topics

Cancer treatment

6 related topics

Interactions

1 related topics

Key facts & relationships

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Aliases
TNFRSF8, CD30, D1S166E, Ki-1, tumor necrosis factor receptor superfamily member 8, TNF receptor superfamily member 8
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D01
Band
1p36.22 · 4 E1|4 78.17 cM
Bgee
granulocyte · monocyte · testicle · blood · pancreatic ductal cell
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

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Overview

Function

Clinical significance

Cancer treatment

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

CD30

Nodes31
Edges30
Triples110
Avg. degree1.94
Density0.064516
Components1

How this topic connects Entity context

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CD30

Top relations

Gene ontology · 23
CD30 → apoptotic signaling pathway, axon guidance, cellular response to mechanical stimulus, cytoplasm, extracellular exosome, immune response, inflammatory response, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of cell population proliferation, negative regulation of neuron projection development, nerve growth factor binding, neuron projection, nucleus, plasma membrane, positive regulation of apoptotic process, positive regulation of NF-kappaB transcription factor activity, response to lipopolysaccharide, signal transduction
Bgee · 19
CD30 → appendix, blastocyst, blood, decidua, dentate gyrus of hippocampal formation granule cell, embryo, granulocyte, monocyte, morula, neural layer of retina, pancreatic ductal cell, periodontal fiber, primary oocyte, right auricle of heart, secondary oocyte, subcutaneous adipose tissue, testicle, thymus, zygote
RNA expression pattern · 19
CD30 → appendix, blastocyst, blood, decidua, dentate gyrus of hippocampal formation granule cell, embryo, granulocyte, monocyte, morula, neural layer of retina, pancreatic ductal cell, periodontal fiber, primary oocyte, right auricle of heart, secondary oocyte, subcutaneous adipose tissue, testicle, thymus, zygote
related to External links · 10
CD30 → Antigens, Human TNFRSF8, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, TNFRSF8, UCSC Genome Browser, United States National Library
has treatment · 9
CD30 → Adcetris, ASCT, CD30-expressing, CD30-positive, FDA, HL, Hodgkin, It, MF
related to Clinical significance · 5
CD30 → CD15, Hodgkin's, It, Reed, Sternberg
Band · 2
CD30 → 1p36.22, 4 E1|4 78.17 cM
Chr. · 2
CD30 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
CD30 → 12,144,207 bp, 145,041,734 bp
related to Interactions · 2
CD30 → TRAF2, TRAF5

Important terminology Word statistics

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Important terminology

bp gene cell human chr band receptor tumor tnfrsf8 chromosome location also lymphoma necrosis factor expressed 144 anaplastic large membrane

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CD30AliasesTNFRSF8, CD30, D1S166E, Ki-1, tumor necrosis factor receptor superfamily member 8, TNF receptor superfamily member 81.00infobox
CD30Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D011.00infobox
CD30Band1p36.221.00infobox
CD30Band4 E1|4 78.17 cM1.00infobox
CD30Bgeegranulocyte1.00infobox
CD30Bgeemonocyte1.00infobox
CD30Bgeetesticle1.00infobox
CD30Bgeeblood1.00infobox
CD30Bgeepancreatic ductal cell1.00infobox
CD30Bgeedecidua1.00infobox
CD30Bgeesubcutaneous adipose tissue1.00infobox
CD30Bgeeperiodontal fiber1.00infobox
CD30Bgeeappendix1.00infobox
CD30Bgeeright auricle of heart1.00infobox
CD30Bgeeneural layer of retina1.00infobox
CD30Bgeeblastocyst1.00infobox
CD30Bgeesecondary oocyte1.00infobox
CD30Bgeeembryo1.00infobox
CD30Bgeezygote1.00infobox
CD30Bgeemorula1.00infobox
CD30Bgeethymus1.00infobox
CD30Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
CD30Bgeeprimary oocyte1.00infobox
CD30BioGPSMore reference expression data1.00infobox
CD30Chr.Chromosome 1 (human)1.00infobox
CD30Chr.Chromosome 4 (mouse)1.00infobox
CD30DatabasesNCBI: entry; OMA: entry1.00infobox
CD30End12,144,207 bp1.00infobox
CD30End145,041,734 bp1.00infobox
CD30EnsemblENSG000001209491.00infobox

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