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TNF receptor superfamily member 8, also known as CD30, is a cell membrane protein of the tumor necrosis factor receptor family encoded by the TNFRSF8 gene. It is a tumor marker for Hodgkin lymphoma and anaplastic large cell lymphoma.
The analysis highlights Function, Clinical significance and Cancer treatment as prominent areas in the source structure around CD30.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CD30 shows recurring relationship patterns in the source. For example, CD30 → apoptotic signaling pathway, axon guidance, cellular response to mechanical stimulus, cytoplasm, extracellular exosome, immune response, inflammatory response, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of cell population proliferation, negative regulation of neuron projection development, nerve growth factor binding, neuron projection, nucleus, plasma membrane, positive regulation of apoptotic process, positive regulation of NF-kappaB transcription factor activity, response to lipopolysaccharide, signal transduction Another extracted example is CD30 → appendix, blastocyst, blood, decidua, dentate gyrus of hippocampal formation granule cell, embryo, granulocyte, monocyte, morula, neural layer of retina, pancreatic ductal cell, periodontal fiber, primary oocyte, right auricle of heart, secondary oocyte, subcutaneous adipose tissue, testicle, thymus, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene cell human chr band receptor tumor tnfrsf8 chromosome location also lymphoma necrosis factor expressed 144 anaplastic large membrane
TTTA extracted 110 structured relationships around CD30. Examples in this analysis include CD30 → Aliases → TNFRSF8, CD30, D1S166E, Ki-1, tumor necrosis factor receptor superfamily member 8, TNF receptor superfamily member 8 and CD30 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D01. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD30 | Aliases | TNFRSF8, CD30, D1S166E, Ki-1, tumor necrosis factor receptor superfamily member 8, TNF receptor superfamily member 8 | 1.00 | infobox |
| CD30 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D01 | 1.00 | infobox |
| CD30 | Band | 1p36.22 | 1.00 | infobox |
| CD30 | Band | 4 E1|4 78.17 cM | 1.00 | infobox |
| CD30 | Bgee | granulocyte | 1.00 | infobox |
| CD30 | Bgee | monocyte | 1.00 | infobox |
| CD30 | Bgee | testicle | 1.00 | infobox |
| CD30 | Bgee | blood | 1.00 | infobox |
| CD30 | Bgee | pancreatic ductal cell | 1.00 | infobox |
| CD30 | Bgee | decidua | 1.00 | infobox |
| CD30 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| CD30 | Bgee | periodontal fiber | 1.00 | infobox |
| CD30 | Bgee | appendix | 1.00 | infobox |
| CD30 | Bgee | right auricle of heart | 1.00 | infobox |
| CD30 | Bgee | neural layer of retina | 1.00 | infobox |
| CD30 | Bgee | blastocyst | 1.00 | infobox |
| CD30 | Bgee | secondary oocyte | 1.00 | infobox |
| CD30 | Bgee | embryo | 1.00 | infobox |
| CD30 | Bgee | zygote | 1.00 | infobox |
| CD30 | Bgee | morula | 1.00 | infobox |
| CD30 | Bgee | thymus | 1.00 | infobox |
| CD30 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| CD30 | Bgee | primary oocyte | 1.00 | infobox |
| CD30 | BioGPS | More reference expression data | 1.00 | infobox |
| CD30 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| CD30 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| CD30 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD30 | End | 12,144,207 bp | 1.00 | infobox |
| CD30 | End | 145,041,734 bp | 1.00 | infobox |
| CD30 | Ensembl | ENSG00000120949 | 1.00 | infobox |
The concept neighborhoods around CD30 bring nearby vocabulary together. In this analysis, examples include Lymphoma, Cell and Member. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CD30, one of the stronger structural bridges in this analysis connects CD30 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CD30 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Cancer treatment, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CD30 · EN edition · Analysis: TopicsToTalkAbout