Calcium/calmodulin-dependent protein kinase type II subunit alpha…

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Function

Serine/threonine-specific protein kinase Ca2+Synaptic plasticity Glutamatergic Bruno Reversade

7 related topics

Interactions

Interact Actinin alpha 4 CDK5R1 DLG1

4 related topics

Overview

CamKII Protein kinase Enzyme Phosphorylates Proteins

6 related topics

Key facts & relationships

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2.7.11.17: ↗
Aliases: CAMK2A, CAMKA, calcium/calmodulin dependent protein kinase II alpha, MRD53, CaMKIINalpha, MRT63, CaMKIIalpha
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2VZ6, 3SOA, 5IG3
Band: 5q32 · 18 E1|18 34.41 cM
Bgee: amygdala · prefrontal cortex · right frontal lobe · Region I of hippocampus proper · Brodmann area 9
BioGPS: n/a

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Overview

CamKII Ca2+/calmodulin-dependent protein kinase II
Protein kinase
Enzyme
Phosphorylates Phosphorylation
Proteins Protein
Gene

Function

Serine/threonine-specific protein kinase
Ca2+ Calcium in biology
Synaptic plasticity
Glutamatergic Glutamate (neurotransmitter)
Bruno Reversade
Intellectual disability
Growth retardation

Interactions

Interact Protein-protein interaction
Actinin alpha 4
CDK5R1
DLG1

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Calcium/calmodulin-dependent protein kinase type II subunit alpha

Nodes21

Edges20

Triples126

Avg. degree1.9

Density0.095238

Components1

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Calcium/calmodulin-dependent protein kinase type II subunit alpha

Top relations

Gene ontology · 61

Calcium/calmodulin-dependent protein kinase type II subunit alpha → angiotensin-activated signaling pathway, ATP binding, calcium ion transport, calcium- and calmodulin-dependent protein kinase complex, calcium-dependent protein serine/threonine kinase activity, calmodulin binding, calmodulin-dependent protein kinase activity, cell differentiation, cell junction, cell projection, cytoplasm, cytosol, dendrite, dendrite morphogenesis, dendritic spine, dendritic spine development, endocytic vesicle membrane, G1 phase, G1/S transition of mitotic cell cycle, glutamate receptor binding

Bgee · 20

Calcium/calmodulin-dependent protein kinase type II subunit alpha → amygdala, anterior amygdaloid area, anterior cingulate cortex, Brodmann area 46, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, frontal pole, lateral septal nucleus, muscle of thigh, olfactory tubercle, orbitofrontal cortex, perirhinal cortex, piriform cortex, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, subiculum, superior frontal gyrus

RNA expression pattern · 20

Band · 2

Calcium/calmodulin-dependent protein kinase type II subunit alpha → 18 E1|18 34.41 cM, 5q32

Chr. · 2

Calcium/calmodulin-dependent protein kinase type II subunit alpha → Chromosome 18 (mouse), Chromosome 5 (human)

End · 2

Calcium/calmodulin-dependent protein kinase type II subunit alpha → 150,290,093 bp, 61,121,224 bp

2.7.11.17 · 1

Calcium/calmodulin-dependent protein kinase type II subunit alpha → ↗

Aliases · 1

Calcium/calmodulin-dependent protein kinase type II subunit alpha → CAMK2A, CAMKA, calcium/calmodulin dependent protein kinase II alpha, MRD53, CaMKIINalpha, MRT63, CaMKIIalpha

Available structures · 1

Calcium/calmodulin-dependent protein kinase type II subunit alpha → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2VZ6, 3SOA, 5IG3

BioGPS · 1

Calcium/calmodulin-dependent protein kinase type II subunit alpha → n/a

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Important terminology

gene camk2a protein bp alpha human kinase chr band calmodulin-dependent ii enzyme chromosome location calcium ca2 activity subunit mouse function

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Calcium/calmodulin-dependent protein kinase type II subunit alpha	2.7.11.17	↗	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Aliases	CAMK2A, CAMKA, calcium/calmodulin dependent protein kinase II alpha, MRD53, CaMKIINalpha, MRT63, CaMKIIalpha	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2VZ6, 3SOA, 5IG3	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Band	5q32	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Band	18 E1\|18 34.41 cM	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	amygdala	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	prefrontal cortex	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	right frontal lobe	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	Region I of hippocampus proper	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	Brodmann area 9	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	cingulate gyrus	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	anterior cingulate cortex	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	frontal pole	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	orbitofrontal cortex	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	Brodmann area 46	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	superior frontal gyrus	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	lateral septal nucleus	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	olfactory tubercle	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	muscle of thigh	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	anterior amygdaloid area	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	piriform cortex	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	subiculum	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	primary visual cortex	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Bgee	perirhinal cortex	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	BioGPS	n/a	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Chr.	Chromosome 5 (human)	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Chr.	Chromosome 18 (mouse)	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Databases	NCBI: entry; OMA: entry	1.00	infobox
Calcium/calmodulin-dependent protein kinase type II subunit alpha	End	150,290,093 bp	1.00	infobox

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