BTLA

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BTLA topic overview

The analysis highlights Expression, Function and Clinical significance as prominent areas in the source structure around BTLA.

Related topics: 45
Source areas: 5
Connected nodes: 50
Extracted relationships: 155
Concept neighborhoods: 24
Bridge connections: 50

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Expression · 12 topics

Overview · 10 topics

Function · 9 topics

Clinical significance · 8 topics

Structure · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: BTLA, BTLA1, CD272, B and T lymphocyte associated
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AW2
Band: 3q13.2 · 16|16 B5
Bgee: lymph node · appendix · testicle · granulocyte · spleen
BioGPS: n/a
Chr.: Chromosome 3 (human) · Chromosome 16 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BTLA connects Entity context

The extracted context around BTLA shows recurring relationship patterns in the source. For example, BTLA → appendix, blood, bone marrow, bone marrow cell, embryo, epithelium of colon, gonad, granulocyte, lymph node, mesenteric lymph nodes, mucosa of transverse colon, primitive streak, spleen, subcutaneous adipose tissue, submandibular gland, testicle, thymus Another extracted example is BTLA → As, CD160, Considering, Grb-2, HVEM, Interaction, ITIM, LIGHT, On, PI3K, SHP-1, SHP-2, Taken, The, Therefore, TNFSF14. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Bgee · 17

BTLA → appendix, blood, bone marrow, bone marrow cell, embryo, epithelium of colon, gonad, granulocyte, lymph node, mesenteric lymph nodes, mucosa of transverse colon, primitive streak, spleen, subcutaneous adipose tissue, submandibular gland, testicle, thymus

RNA expression pattern · 17

related to Function · 16

BTLA → As, CD160, Considering, Grb-2, HVEM, Interaction, ITIM, LIGHT, On, PI3K, SHP-1, SHP-2, Taken, The, Therefore, TNFSF14

related to External links · 14

BTLA → Human BTLA, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Overview, PDB, PDBe-KB, Q7Z6A9, T-lymphocyte, This, UCSC Genome Browser, UniProt, United States National Library

related to Infectious diseases · 13

BTLA → As, CD4, CD8, During, Furthermore, However, HVEM, IL-9, Mycobacterium, Similar, Strongyloides, This, When

related to Tumors · 11

BTLA → CD4, CD8, Even, For, Hence, However, IFN-γ, In, Similarly, Therefore, This

Gene ontology · 10

BTLA → adaptive immune response, immune response-regulating cell surface receptor signaling pathway, immune system process, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane, protein binding, signaling receptor activity, T cell costimulation

related to T cell · 10

BTLA → Both BTLA, CD8, For, Furthermore, However, HVEM, PD-1, This, Treg, When

related to Structure · 8

BTLA → CTLA-4, Grb-2, It, ITIM, ITSM, PD-1, The, Therefore

related to Expression · 7

BTLA → Among, DCs, For, If, In, NKT, On

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cells hvem expression cell human also bp cd8 chromosome gene chr band function interaction seems however protein location instance connected

BTLA relationships Subject–Predicate–Object triples

TTTA extracted 155 structured relationships around BTLA. Examples in this analysis include BTLA → Aliases → BTLA, BTLA1, CD272, B and T lymphocyte associated and BTLA → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AW2. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
BTLA	Aliases	BTLA, BTLA1, CD272, B and T lymphocyte associated	1.00	infobox
BTLA	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AW2	1.00	infobox
BTLA	Band	3q13.2	1.00	infobox
BTLA	Band	16\|16 B5	1.00	infobox
BTLA	Bgee	lymph node	1.00	infobox
BTLA	Bgee	appendix	1.00	infobox
BTLA	Bgee	testicle	1.00	infobox
BTLA	Bgee	granulocyte	1.00	infobox
BTLA	Bgee	spleen	1.00	infobox
BTLA	Bgee	bone marrow cell	1.00	infobox
BTLA	Bgee	blood	1.00	infobox
BTLA	Bgee	mucosa of transverse colon	1.00	infobox
BTLA	Bgee	gonad	1.00	infobox
BTLA	Bgee	epithelium of colon	1.00	infobox
BTLA	Bgee	mesenteric lymph nodes	1.00	infobox
BTLA	Bgee	subcutaneous adipose tissue	1.00	infobox
BTLA	Bgee	submandibular gland	1.00	infobox
BTLA	Bgee	primitive streak	1.00	infobox
BTLA	Bgee	thymus	1.00	infobox
BTLA	Bgee	embryo	1.00	infobox
BTLA	Bgee	bone marrow	1.00	infobox
BTLA	BioGPS	n/a	1.00	infobox
BTLA	Chr.	Chromosome 3 (human)	1.00	infobox
BTLA	Chr.	Chromosome 16 (mouse)	1.00	infobox
BTLA	Databases	NCBI: entry; OMA: entry	1.00	infobox
BTLA	End	112,499,472 bp	1.00	infobox
BTLA	End	45,078,033 bp	1.00	infobox
BTLA	Ensembl	ENSG00000186265	1.00	infobox
BTLA	Entrez	151888	1.00	infobox
BTLA	External IDs	OMIM: 607925; MGI: 2658978; GeneCards: BTLA	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BTLA bring nearby vocabulary together. In this analysis, examples include Cells, Expression and Cell. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

BTLA
- Cells
- Expression
- Cell
- Hvem
- Cd8
- Seems
- Human
- Connected
- Function
- Instance
- Interaction
- Case
btla
- Cells
- Expression
- Cell
- Hvem
- Cd8
- Seems
- Human
- Connected
- Function
- Instance
- Interaction
- Case
expression
- Cells
- Cell
- Lower
- Connected
- Function
- Instance
- Human
- Dcs
- Expressed
- Location
- Bp
- Chr
t cell
- Expression
- Cells
- Function
- Expressed
- Location
- Protein
- Bp
- Chr
- Chromosome
- Connected
- Gene
- Human
cd8+ t cells
- Cd8
- Cells
- Expression
- Connected
- Instance
- Hvem
- Case
- Virus
- Interaction
- Dcs
- Expressed
- Inhibitory
b cells
- Cd8
- Expression
- Hvem
- Case
- Instance
- Connected
- Interaction
- Dcs
- Expressed
- Lower
- Virus
- Function
nkt cells
- Cd8
- Expression
- Hvem
- Case
- Instance
- Connected
- Interaction
- Dcs
- Expressed
- Lower
- Virus
- Function
naive t cells
- Cd8
- Expression
- Hvem
- Case
- Instance
- Connected
- Interaction
- Dcs
- Expressed
- Lower
- Virus
- Function

Connections between topic areas Semantic bridges

For BTLA, one of the stronger structural bridges in this analysis connects BTLA with Expression. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

BTLA — Expression · splits 38 ⟂ 13

BTLA — Overview · splits 40 ⟂ 11

BTLA — Function · splits 41 ⟂ 10

BTLA — Clinical significance · splits 42 ⟂ 9

BTLA — Structure · splits 44 ⟂ 7

Map overview Semantic statistics

BTLA

Nodes51

Edges50

Triples155

Avg. degree1.96

Density0.039216

Components1

Source & methodology

TTTA analyzes the structure around BTLA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Expression, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BTLA · EN edition · Analysis: TopicsToTalkAbout