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Beta-actin: Applications & Standards

Beta-actin, or Actin beta (HUGO Gene Nomenclature Committee abbreviation ACTB/ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the…

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Beta-actin topic overview

The analysis highlights Applications and Standards as prominent areas in the source structure around Beta-actin.

Related topics
13
Source areas
4
Connected nodes
17
Extracted relationships
99
Concept neighborhoods
7
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical relevance · 4 topics
Interactions · 4 topics
Applications · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE
Band
7p22.1 · 5 G2|5 81.8 cM
Bgee
saphenous vein · urethra · postcentral gyrus · synovial joint · orbitofrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Clinical relevance

Applications

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Beta-actin connects Entity context

The extracted context around Beta-actin shows recurring relationship patterns in the source. For example, Beta-actin → ATP binding, blood microparticle, cell junction assembly, cortical cytoskeleton, cytoplasm, cytoplasmic ribonucleoprotein granule, cytoskeleton, cytoskeleton organization, cytosol, dense body, ephrin receptor signaling pathway, epigenetic maintenance of chromatin in transcription-competent conformation, extracellular exosome, extracellular space, Fc-gamma receptor signaling pathway involved in phagocytosis, focal adhesion, identical protein binding, kinesin binding, membrane, membrane organization Another extracted example is Beta-actin → abdominal wall, Brodmann area 46, Gonadal ridge, human fetus, lateral septal nucleus, mandibular prominence, maxillary prominence, medial ganglionic eminence, migratory enteric neural crest cell, mucosa of ileum, nipple, olfactory bulb, orbitofrontal cortex, postcentral gyrus, saphenous vein, synovial joint, urethra, vas deferens, vena cava, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.

Beta-actin

Top relations

Gene ontology · 36
Beta-actin → ATP binding, blood microparticle, cell junction assembly, cortical cytoskeleton, cytoplasm, cytoplasmic ribonucleoprotein granule, cytoskeleton, cytoskeleton organization, cytosol, dense body, ephrin receptor signaling pathway, epigenetic maintenance of chromatin in transcription-competent conformation, extracellular exosome, extracellular space, Fc-gamma receptor signaling pathway involved in phagocytosis, focal adhesion, identical protein binding, kinesin binding, membrane, membrane organization
Bgee · 20
Beta-actin → abdominal wall, Brodmann area 46, Gonadal ridge, human fetus, lateral septal nucleus, mandibular prominence, maxillary prominence, medial ganglionic eminence, migratory enteric neural crest cell, mucosa of ileum, nipple, olfactory bulb, orbitofrontal cortex, postcentral gyrus, saphenous vein, synovial joint, urethra, vas deferens, vena cava, ventromedial nucleus
RNA expression pattern · 20
Beta-actin → abdominal wall, Brodmann area 46, Gonadal ridge, human fetus, lateral septal nucleus, mandibular prominence, maxillary prominence, medial ganglionic eminence, migratory enteric neural crest cell, mucosa of ileum, nipple, olfactory bulb, orbitofrontal cortex, postcentral gyrus, saphenous vein, synovial joint, urethra, vas deferens, vena cava, ventromedial nucleus
Band · 2
Beta-actin → 5 G2|5 81.8 cM, 7p22.1
Chr. · 2
Beta-actin → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
Beta-actin → 142,892,509 bp, 5,563,902 bp
Aliases · 1
Beta-actin → ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta
Available structures · 1
Beta-actin → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE
BioGPS · 1
Beta-actin → More reference expression data
Databases · 1
Beta-actin → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

actin gene bp human beta chr actb band chromosome actins location one mouse protein involved cell constituent cytoskeletal external pdb

Beta-actin relationships Subject–Predicate–Object triples

TTTA extracted 99 structured relationships around Beta-actin. Examples in this analysis include Beta-actin → Aliases → ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta and Beta-actin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Beta-actinAliasesACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta1.00infobox
Beta-actinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE1.00infobox
Beta-actinBand7p22.11.00infobox
Beta-actinBand5 G2|5 81.8 cM1.00infobox
Beta-actinBgeesaphenous vein1.00infobox
Beta-actinBgeeurethra1.00infobox
Beta-actinBgeepostcentral gyrus1.00infobox
Beta-actinBgeesynovial joint1.00infobox
Beta-actinBgeeorbitofrontal cortex1.00infobox
Beta-actinBgeemucosa of ileum1.00infobox
Beta-actinBgeeBrodmann area 461.00infobox
Beta-actinBgeenipple1.00infobox
Beta-actinBgeevena cava1.00infobox
Beta-actinBgeeolfactory bulb1.00infobox
Beta-actinBgeehuman fetus1.00infobox
Beta-actinBgeevas deferens1.00infobox
Beta-actinBgeelateral septal nucleus1.00infobox
Beta-actinBgeeGonadal ridge1.00infobox
Beta-actinBgeemandibular prominence1.00infobox
Beta-actinBgeemigratory enteric neural crest cell1.00infobox
Beta-actinBgeemaxillary prominence1.00infobox
Beta-actinBgeeventromedial nucleus1.00infobox
Beta-actinBgeeabdominal wall1.00infobox
Beta-actinBgeemedial ganglionic eminence1.00infobox
Beta-actinBioGPSMore reference expression data1.00infobox
Beta-actinChr.Chromosome 7 (human)1.00infobox
Beta-actinChr.Chromosome 5 (mouse)1.00infobox
Beta-actinDatabasesNCBI: entry; OMA: entry1.00infobox
Beta-actinEnd5,563,902 bp1.00infobox
Beta-actinEnd142,892,509 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Beta-actin bring nearby vocabulary together. In this analysis, examples include Actb, External and Also. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • actin
    • Beta
    • Protein
    • Shown
    • Actb
    • Available
    • Beta-actin
    • Cytoplasmic
    • Enos
    • Interact
    • Mrna
    • P60709
    • Pdb
  • Beta-actin
    • Actb
    • External
    • Also
    • Available
    • One
    • Pdb
    • Search
    • Gene
    • Chromosome
    • Location
    • Bp
    • Chr
  • beta-actin
    • Actb
    • External
    • Also
    • Available
    • One
    • Pdb
    • Search
    • Gene
    • Chromosome
    • Location
    • Bp
    • Chr
  • interact
    • Mrna
    • Protein
    • Involved
    • Molecular
    • Mouse
    • P60709
    • Search
    • Structural
    • Uniprot
    • Shown
    • Location
  • rna-binding protein
    • Mrna
    • P60709
    • Search
    • Structural
    • Uniprot
    • Shown
  • cytoskeletal
    • Interact
    • Mrna
    • One
    • Actins
    • Protein
  • enos
    • Shown

Connections between topic areas Semantic bridges

For Beta-actin, one of the stronger structural bridges in this analysis connects Beta-actin with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Beta-actin — Interactions · splits 13 ⟂ 5
Beta-actin — Clinical relevance · splits 13 ⟂ 5
Beta-actin — Applications · splits 14 ⟂ 4
Beta-actin — Overview · splits 15 ⟂ 3

Map overview Semantic statistics

Beta-actin

Nodes18
Edges17
Triples99
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around Beta-actin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Beta-actin · EN edition · Analysis: TopicsToTalkAbout

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