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Automated patch clamp

Automated patch clamping is beginning to replace manual patch clamping as a method to measure the electrical activity of individual cells. Different techniques are used to automate patch clamp recordings from cells in cell culture and in vivo. This work has been ongoing since the late 1990s by research labs and companies trying to reduce its complexity…

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Overview

Manual patch clamp

Automation systems

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Automated patch clamp

Nodes39
Edges38
Triples10
Avg. degree1.95
Density0.051282
Components1

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Automated patch clamp

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related to In culture · 3
Automated patch clamp → By, One, There

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Important terminology

cells pipette patch cell clamping technician culture suspension manual clamp automation electrical vivo membrane tip form recordings systems seal gigaseal

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
voltage-gated sodium channelsinstance ofIon channels0.80text
voltage-gated potassium channelsinstance ofIon channels0.80text
ionotropic ligand-gated ion channels opened by the ligand GABA were recorded from these cells using automatedinstance ofIon channels0.80text
manual patch clamp.In cultureThere are many in vitro methods for the automated patch clamping of cultured cells or slices of brain tissue.One uses a patch chipinstance ofIon channels0.80text
like those discussed aboveinstance ofIon channels0.80text
along with surface treatments that cause the cultured cells to migrate to the orifices where the gigaseal is formed as they growinstance ofIon channels0.80text
manual patch clampinstance ofIon channels0.80text
Automated patch clamprelated to In cultureThere0.60section
Automated patch clamprelated to In cultureOne0.60section
Automated patch clamprelated to In cultureBy0.60section

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