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Active ester

In organic chemistry, an active ester is an ester functional group that is highly susceptible toward nucleophilic attack. Activation can be imparted by modifications of the acyl or the alkoxy components of a normal ester, say ethyl acetate. Typical modifications call for electronegative substituents. Active esters are employed in both synthetic and…

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Active ester

Nodes28
Edges27
Triples11
Avg. degree1.93
Density0.071429
Components1

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Active ester

Top relations

related to Biochemistry · 4
Active ester → Active, Glutamine, Thioesters, This
related to Reactivity · 3
Active ester → Active, Of, They
related to Synthetic chemistry · 3
Active ester → Classically, Hydroxybenzotriazole, These
is a · 1
Active ester → ester functional group that is highly susceptible toward nucleophilic attack

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Important terminology

active esters ester chemistry modifications synthetic toward activation imparted acyl reactivity biochemistry glutamine used rapidly prominent carboxylate acid organic functional

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Active esteris aester functional group that is highly susceptible toward nucleophilic attack0.90text
Active esterrelated to BiochemistryActive0.60section
Active esterrelated to BiochemistryGlutamine0.60section
Active esterrelated to BiochemistryThis0.60section
Active esterrelated to BiochemistryThioesters0.60section
Active esterrelated to ReactivityActive0.60section
Active esterrelated to ReactivityThey0.60section
Active esterrelated to ReactivityOf0.60section
Active esterrelated to Synthetic chemistryHydroxybenzotriazole0.60section
Active esterrelated to Synthetic chemistryClassically0.60section
Active esterrelated to Synthetic chemistryThese0.60section

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    Min side: 3
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