Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

5-APDB: History, Pharmacology & Overview

5-APDB, also known as 5-(2-aminopropyl)-2,3-dihydrobenzofuran or as 3-desoxy-MDA, is an entactogen of the phenethylamine, amphetamine, and dihydrobenzofuran families. It is an analogue of MDA where the heterocyclic 3-position oxygen from the 3,4-methylenedioxy ring has been replaced by a methylene bridge. 6-APDB is an analogue of 5-APDB where the…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

5-APDB topic overview

The analysis highlights History, Pharmacology and Overview as prominent areas in the source structure around 5-APDB. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
49
Source areas
4
Connected nodes
54
Extracted relationships
57
Concept neighborhoods
24
Bridge connections
54

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 20 topics
Pharmacology · 16 topics
Chemistry · 7 topics
History · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
None
CAS Number
152624-03-8 N
ChemSpider
167143 N
CompTox Dashboard (EPA)
DTXSID70934560
Drug class
Entactogen; Serotonin releasing agent; Serotonin receptor modulator

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Pharmacology

Chemistry

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How 5-APDB connects Entity context

The extracted context around 5-APDB shows recurring relationship patterns in the source. For example, 5-APDB → APB, APDB, Company, David, Eli Lilly, HT2C, MDMA, Nichols, Prior, Purdue University, Subsequently Another extracted example is 5-APDB → APDB, APDB's, IC50, In, It, LSD, MBDB, MDMA, MMAI, SSRA. Use these groups to spot repeated connection types before inspecting the individual relationships.

5-APDB

Top relations

related to history · 11
5-APDB → APB, APDB, Company, David, Eli Lilly, HT2C, MDMA, Nichols, Prior, Purdue University, Subsequently
related to Pharmacodynamics · 10
5-APDB → APDB, APDB's, IC50, In, It, LSD, MBDB, MDMA, MMAI, SSRA
related to Analogues · 6
5-APDB → APDB, DOM, In, MDA, MDMA, Methoxy-substituted
related to External links · 5
5-APDB → APDB, APDB Thread, Bluelight, Dandy, Isomer DesignThe Big
Legal status · 4
5-APDB → BR: Class F2 (Prohibited psychotropics), CA: Schedule I, DE: NpSG (Industrial and scientific use only), UK: Class B
is a · 2
5-APDB → controlled substance in China, controlled substance in China.United KingdomOn June 10
related to Chemistry · 2
5-APDB → APDB, MDA
related to Synthesis · 2
5-APDB → APDB, The
3D model (JSmol) · 1
5-APDB → Interactive image
ATC code · 1
5-APDB → None

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

analogue 6-apdb also analogues mdma serotonin described phenethylamine amphetamine 5- 2-aminopropyl mda entactogen controlled substance oxygen replaced methylene bridge 5-apb

5-APDB relationships Subject–Predicate–Object triples

TTTA extracted 57 structured relationships around 5-APDB. Examples in this analysis include 5-APDB → 3D model (JSmol) → Interactive image and 5-APDB → ATC code → None. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
5-APDB3D model (JSmol)Interactive image1.00infobox
5-APDBATC codeNone1.00infobox
5-APDBCAS Number152624-03-8 N1.00infobox
5-APDBChemSpider167143 N1.00infobox
5-APDBCompTox Dashboard (EPA)DTXSID709345601.00infobox
5-APDBDrug classEntactogen; Serotonin releasing agent; Serotonin receptor modulator1.00infobox
5-APDBFormulaC11H15NO1.00infobox
5-APDBLegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
5-APDBLegal statusCA: Schedule I1.00infobox
5-APDBLegal statusDE: NpSG (Industrial and scientific use only)1.00infobox
5-APDBLegal statusUK: Class B1.00infobox
5-APDBMolar mass177.247 g·mol−11.00infobox
5-APDBOther names5-(2-Aminopropyl)-2,3-dihydrobenzofuran; 3-Desoxy-MDA; EMA-4; BF5AP1.00infobox
5-APDBPubChem CID1926011.00infobox
5-APDBRoutes of administrationOral1.00infobox
5-APDBUNIIUI10BAJ8SH1.00infobox
5-APDBis acontrolled substance in China.United KingdomOn June 100.90text
5-APDBis acontrolled substance in China0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around 5-APDB bring nearby vocabulary together. In this analysis, examples include 6-apdb, Also and 2-aminopropyl. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • 5-APDB
    • 6-apdb
    • Also
    • 2-aminopropyl
    • 5-
    • Amphetamine
    • Phenethylamine
    • Analogues
    • Controlled
    • Substance
    • -2
    • 3-desoxy-mda
    • 3-dihydrobenzofuran
  • 5-apdb
    • 6-apdb
    • Also
    • 2-aminopropyl
    • 5-
    • Amphetamine
    • Phenethylamine
    • Analogues
    • Controlled
    • Substance
    • -2
    • 3-desoxy-mda
    • 3-dihydrobenzofuran
  • united states
    • Legal
    • Status
    • -2
    • 3-desoxy-mda
    • 3-dihydrobenzofuran
    • Canada
    • China
    • Entactogen
    • Synthesis
    • 2-aminopropyl
    • 5-
    • Amphetamine
  • amphetamine
    • Entactogen
    • Known
    • Phenethylamine
    • Legal
    • Status
    • Canada
    • China
    • Synthesis
    • United
    • Class
    • Mda
    • Analogues
  • analogue
    • Bridge
    • Methylene
    • Oxygen
    • Replaced
    • Mda
    • Known
    • Nichols
    • Purdue
    • University
    • Phenethylamine
    • Controlled
    • Mdma
  • federal analogue act
    • Bridge
    • Methylene
    • Oxygen
    • Replaced
    • Mda
    • Known
    • Nichols
    • Purdue
    • University
    • Phenethylamine
    • Controlled
    • Mdma
  • entactogen
    • Amphetamine
    • Legal
    • Status
    • Canada
    • China
    • Known
    • Synthesis
    • United
    • Class
    • Phenethylamine
    • Analogues
    • Mdma
  • mdma
    • Nichols
    • Purdue
    • University
    • Legal
    • Status
    • Canada
    • China
    • First
    • Synthesis
    • United
    • Class
    • Described

Connections between topic areas Semantic bridges

For 5-APDB, one of the stronger structural bridges in this analysis connects 5-APDB with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
5-APDBOverview · splits 34 ⟂ 21
5-APDBPharmacology · splits 38 ⟂ 17
5-APDBChemistry · splits 47 ⟂ 8
5-APDBHistory · splits 47 ⟂ 8

Map overview Semantic statistics

5-APDB

Nodes55
Edges54
Triples57
Avg. degree1.96
Density0.036364
Components1

Source & methodology

TTTA analyzes the structure around 5-APDB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Pharmacology & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — 5-APDB · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.