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5′-3′ exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. Xrn1 hydrolyses RNA in the 5′ to 3′ direction.
The analysis highlights Function and Overview as prominent areas in the source structure around XRN1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around XRN1 shows recurring relationship patterns in the source. For example, XRN1 → 5'-3' exonuclease activity, 5'-3' exoribonuclease activity, cellular response to cycloheximide, cellular response to puromycin, cytoplasm, cytosol, dendrite, DNA binding, exonuclease activity, G-quadruplex DNA binding, G-quadruplex RNA binding, histone mRNA catabolic process, hydrolase activity, membrane, negative regulation of telomere maintenance via telomerase, negative regulation of translation, nuclear mRNA surveillance, nuclear-transcribed mRNA catabolic process, nuclease activity, nucleic acid binding Another extracted example is XRN1 → Achilles tendon, bone marrow cell, cumulus cell, endothelial cell, genital tubercle, germinal epithelium, gingival epithelium, granulocyte, palpebral conjunctiva, pancreatic epithelial cell, parietal pleura, pineal gland, Rostral migratory stream, secondary oocyte, tail of embryo, thymus, tibia, vas deferens, visceral pleura, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene chr human band protein chromosome exoribonuclease location mrna encoded rna mouse function -3 5'-3' 448 062 end 142
TTTA extracted 92 structured relationships around XRN1. Examples in this analysis include XRN1 → Aliases → XRN1, SEP1, 5'-3' exoribonuclease 1, Xrn1 and XRN1 → Band → 3q23. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| XRN1 | Aliases | XRN1, SEP1, 5'-3' exoribonuclease 1, Xrn1 | 1.00 | infobox |
| XRN1 | Band | 3q23 | 1.00 | infobox |
| XRN1 | Band | 9|9 E3.3 | 1.00 | infobox |
| XRN1 | Bgee | pancreatic epithelial cell | 1.00 | infobox |
| XRN1 | Bgee | Achilles tendon | 1.00 | infobox |
| XRN1 | Bgee | germinal epithelium | 1.00 | infobox |
| XRN1 | Bgee | visceral pleura | 1.00 | infobox |
| XRN1 | Bgee | parietal pleura | 1.00 | infobox |
| XRN1 | Bgee | tibia | 1.00 | infobox |
| XRN1 | Bgee | bone marrow cell | 1.00 | infobox |
| XRN1 | Bgee | gingival epithelium | 1.00 | infobox |
| XRN1 | Bgee | endothelial cell | 1.00 | infobox |
| XRN1 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| XRN1 | Bgee | tail of embryo | 1.00 | infobox |
| XRN1 | Bgee | cumulus cell | 1.00 | infobox |
| XRN1 | Bgee | Rostral migratory stream | 1.00 | infobox |
| XRN1 | Bgee | thymus | 1.00 | infobox |
| XRN1 | Bgee | genital tubercle | 1.00 | infobox |
| XRN1 | Bgee | zygote | 1.00 | infobox |
| XRN1 | Bgee | pineal gland | 1.00 | infobox |
| XRN1 | Bgee | secondary oocyte | 1.00 | infobox |
| XRN1 | Bgee | vas deferens | 1.00 | infobox |
| XRN1 | Bgee | granulocyte | 1.00 | infobox |
| XRN1 | BioGPS | n/a | 1.00 | infobox |
| XRN1 | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| XRN1 | Chr. | Chromosome 9 (mouse) | 1.00 | infobox |
| XRN1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| XRN1 | End | 142,448,062 bp | 1.00 | infobox |
| XRN1 | End | 95,939,856 bp | 1.00 | infobox |
| XRN1 | Ensembl | ENSG00000114127 | 1.00 | infobox |
The concept neighborhoods around XRN1 bring nearby vocabulary together. In this analysis, examples include Exoribonuclease, -3 and 5'-3'. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For XRN1, one of the stronger structural bridges in this analysis connects XRN1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around XRN1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — XRN1 · EN edition · Analysis: TopicsToTalkAbout