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WWOX

WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene.

Interactions, Structure & Function

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Explore the main themes, entities and connections around WWOX. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

3 related topics

Structure

1 related topics

Function

1 related topics

Disorders

1 related topics

Key facts & relationships

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Aliases
WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE28
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WMV
Band
16q23.1-q23.2 · 8|8 E1
Bgee
parotid gland · optic nerve · glomerulus · sural nerve · metanephric glomerulus
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

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Overview

Structure

Function

Interactions

Disorders

Advanced semantic analysis

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Map overview Semantic statistics

WWOX

Nodes14
Edges13
Triples105
Avg. degree1.86
Density0.142857
Components1

How this topic connects Entity context

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WWOX

Top relations

Gene ontology · 27
WWOX → apoptotic process, cellular response to transforming growth factor beta stimulus, cytoplasm, cytosol, enzyme binding, extrinsic apoptotic signaling pathway, Golgi apparatus, intrinsic apoptotic signaling pathway by p53 class mediator, microvillus, mitochondrion, negative regulation of transcription by RNA polymerase II, negative regulation of Wnt signaling pathway, nucleus, osteoblast differentiation, oxidoreductase activity, plasma membrane, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of transcription by RNA polymerase II, protein binding
Bgee · 20
WWOX → amygdala, cerebellar cortex, endothelial cell, Epithelium of choroid plexus, glomerulus, interventricular septum, kidney tubule, lens, metanephric glomerulus, neural layer of retina, optic nerve, parotid gland, pars compacta, pars reticulata, primary visual cortex, secondary oocyte, spermatocyte, sural nerve, visual cortex, zygote
RNA expression pattern · 20
WWOX → amygdala, cerebellar cortex, endothelial cell, Epithelium of choroid plexus, glomerulus, interventricular septum, kidney tubule, lens, metanephric glomerulus, neural layer of retina, optic nerve, parotid gland, pars compacta, pars reticulata, primary visual cortex, secondary oocyte, spermatocyte, sural nerve, visual cortex, zygote
related to Function · 5
WWOX → In, It, SRD, The, This
Band · 2
WWOX → 16q23.1-q23.2, 8|8 E1
Chr. · 2
WWOX → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
WWOX → 116,079,447 bp, 79,212,667 bp
related to Disorders · 2
WWOX → Defects, WOREE
related to Interactions · 2
WWOX → ACK1, P53
Aliases · 1
WWOX → WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE28

Important terminology Word statistics

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Important terminology

gene human bp chr band chromosome 16 ww oxidoreductase mouse protein location role enzyme domain expression function domain-containing humans encoded

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
WWOXAliasesWWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE281.00infobox
WWOXAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WMV1.00infobox
WWOXBand16q23.1-q23.21.00infobox
WWOXBand8|8 E11.00infobox
WWOXBgeeparotid gland1.00infobox
WWOXBgeeoptic nerve1.00infobox
WWOXBgeeglomerulus1.00infobox
WWOXBgeesural nerve1.00infobox
WWOXBgeemetanephric glomerulus1.00infobox
WWOXBgeeEpithelium of choroid plexus1.00infobox
WWOXBgeepars reticulata1.00infobox
WWOXBgeeendothelial cell1.00infobox
WWOXBgeekidney tubule1.00infobox
WWOXBgeepars compacta1.00infobox
WWOXBgeeinterventricular septum1.00infobox
WWOXBgeeneural layer of retina1.00infobox
WWOXBgeezygote1.00infobox
WWOXBgeeamygdala1.00infobox
WWOXBgeevisual cortex1.00infobox
WWOXBgeecerebellar cortex1.00infobox
WWOXBgeesecondary oocyte1.00infobox
WWOXBgeeprimary visual cortex1.00infobox
WWOXBgeespermatocyte1.00infobox
WWOXBgeelens1.00infobox
WWOXBioGPSMore reference expression data1.00infobox
WWOXChr.Chromosome 16 (human)1.00infobox
WWOXChr.Chromosome 8 (mouse)1.00infobox
WWOXDatabasesNCBI: entry; OMA: entry1.00infobox
WWOXEnd79,212,667 bp1.00infobox
WWOXEnd116,079,447 bp1.00infobox

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