Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

WWOX: Interactions, Structure & Function

WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

WWOX topic overview

The analysis highlights Interactions, Structure and Function as prominent areas in the source structure around WWOX.

Related topics
8
Source areas
5
Connected nodes
13
Extracted relationships
105
Concept neighborhoods
9
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 3 topics
Overview · 2 topics
Disorders · 1 topics
Function · 1 topics
Structure · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE28
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WMV
Band
16q23.1-q23.2 · 8|8 E1
Bgee
parotid gland · optic nerve · glomerulus · sural nerve · metanephric glomerulus
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Interactions

Disorders

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How WWOX connects Entity context

The extracted context around WWOX shows recurring relationship patterns in the source. For example, WWOX → apoptotic process, cellular response to transforming growth factor beta stimulus, cytoplasm, cytosol, enzyme binding, extrinsic apoptotic signaling pathway, Golgi apparatus, intrinsic apoptotic signaling pathway by p53 class mediator, microvillus, mitochondrion, negative regulation of transcription by RNA polymerase II, negative regulation of Wnt signaling pathway, nucleus, osteoblast differentiation, oxidoreductase activity, plasma membrane, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of transcription by RNA polymerase II, protein binding Another extracted example is WWOX → amygdala, cerebellar cortex, endothelial cell, Epithelium of choroid plexus, glomerulus, interventricular septum, kidney tubule, lens, metanephric glomerulus, neural layer of retina, optic nerve, parotid gland, pars compacta, pars reticulata, primary visual cortex, secondary oocyte, spermatocyte, sural nerve, visual cortex, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

WWOX

Top relations

Gene ontology · 27
WWOX → apoptotic process, cellular response to transforming growth factor beta stimulus, cytoplasm, cytosol, enzyme binding, extrinsic apoptotic signaling pathway, Golgi apparatus, intrinsic apoptotic signaling pathway by p53 class mediator, microvillus, mitochondrion, negative regulation of transcription by RNA polymerase II, negative regulation of Wnt signaling pathway, nucleus, osteoblast differentiation, oxidoreductase activity, plasma membrane, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of transcription by RNA polymerase II, protein binding
Bgee · 20
WWOX → amygdala, cerebellar cortex, endothelial cell, Epithelium of choroid plexus, glomerulus, interventricular septum, kidney tubule, lens, metanephric glomerulus, neural layer of retina, optic nerve, parotid gland, pars compacta, pars reticulata, primary visual cortex, secondary oocyte, spermatocyte, sural nerve, visual cortex, zygote
RNA expression pattern · 20
WWOX → amygdala, cerebellar cortex, endothelial cell, Epithelium of choroid plexus, glomerulus, interventricular septum, kidney tubule, lens, metanephric glomerulus, neural layer of retina, optic nerve, parotid gland, pars compacta, pars reticulata, primary visual cortex, secondary oocyte, spermatocyte, sural nerve, visual cortex, zygote
related to Function · 5
WWOX → In, It, SRD, The, This
Band · 2
WWOX → 16q23.1-q23.2, 8|8 E1
Chr. · 2
WWOX → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
WWOX → 116,079,447 bp, 79,212,667 bp
related to Disorders · 2
WWOX → Defects, WOREE
related to Interactions · 2
WWOX → ACK1, P53
Aliases · 1
WWOX → WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE28

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp chr band chromosome 16 ww oxidoreductase mouse protein location role enzyme domain expression function domain-containing humans encoded

WWOX relationships Subject–Predicate–Object triples

TTTA extracted 105 structured relationships around WWOX. Examples in this analysis include WWOX → Aliases → WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE28 and WWOX → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WMV. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
WWOXAliasesWWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1, EIEE28, WW domain containing oxidoreductase, DEE281.00infobox
WWOXAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WMV1.00infobox
WWOXBand16q23.1-q23.21.00infobox
WWOXBand8|8 E11.00infobox
WWOXBgeeparotid gland1.00infobox
WWOXBgeeoptic nerve1.00infobox
WWOXBgeeglomerulus1.00infobox
WWOXBgeesural nerve1.00infobox
WWOXBgeemetanephric glomerulus1.00infobox
WWOXBgeeEpithelium of choroid plexus1.00infobox
WWOXBgeepars reticulata1.00infobox
WWOXBgeeendothelial cell1.00infobox
WWOXBgeekidney tubule1.00infobox
WWOXBgeepars compacta1.00infobox
WWOXBgeeinterventricular septum1.00infobox
WWOXBgeeneural layer of retina1.00infobox
WWOXBgeezygote1.00infobox
WWOXBgeeamygdala1.00infobox
WWOXBgeevisual cortex1.00infobox
WWOXBgeecerebellar cortex1.00infobox
WWOXBgeesecondary oocyte1.00infobox
WWOXBgeeprimary visual cortex1.00infobox
WWOXBgeespermatocyte1.00infobox
WWOXBgeelens1.00infobox
WWOXBioGPSMore reference expression data1.00infobox
WWOXChr.Chromosome 16 (human)1.00infobox
WWOXChr.Chromosome 8 (mouse)1.00infobox
WWOXDatabasesNCBI: entry; OMA: entry1.00infobox
WWOXEnd79,212,667 bp1.00infobox
WWOXEnd116,079,447 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around WWOX bring nearby vocabulary together. In this analysis, examples include Oxidoreductase, Gene and Disorders. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • WWOX
    • Oxidoreductase
    • Gene
    • Disorders
    • Enzyme
    • Function
    • Human
    • P53
    • Search
    • Location
    • Chromosome
    • Ww
    • Bp
  • wwox
    • Oxidoreductase
    • Gene
    • Disorders
    • Enzyme
    • Function
    • Human
    • P53
    • Search
    • Location
    • Chromosome
    • Ww
    • Bp
  • enzyme
    • Oxidoreductase
    • Cellular
    • Encoded
    • End
    • Function
    • Growth
    • Humans
    • Mediator
    • P53
    • Pattern
    • Regulation
    • Rna
  • gene
    • Wwox
    • Domain
    • Expression
    • Location
    • Oxidoreductase
    • Chromosome
    • Ww
    • Bp
    • Chr
    • Human
    • 1-q23
    • Disorders
  • ww domain
    • Domain
    • Ww
    • Gene
    • Protein
    • 1-q23
    • Function
    • Pattern
    • Search
    • Steroid
    • Wwox
    • Cellular
    • Disorders
  • function
    • Search
    • Location
    • Oxidoreductase
    • Chromosome
    • Bp
    • Chr
    • 1-q23
    • Cellular
    • Disorders
    • End
    • Growth
    • Human
  • human accelerated region
    • Location
    • Mouse
    • Band
    • End
    • Mediator
    • Search
    • Wwox
    • Oxidoreductase
    • Protein
    • Cellular
    • Growth
    • P53
  • disorders
    • 1-q23
    • Function
    • Search
    • Wwox
    • Domain
    • Location
    • Oxidoreductase
    • Gene
    • Chromosome
    • Ww
    • Bp
    • Chr

Connections between topic areas Semantic bridges

For WWOX, one of the stronger structural bridges in this analysis connects WWOX with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
WWOXInteractions · splits 10 ⟂ 4
WWOXOverview · splits 11 ⟂ 3

Map overview Semantic statistics

WWOX

Nodes14
Edges13
Triples105
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around WWOX to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — WWOX · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.