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VUBI1

VUBI1 is a drug that acts as an activator of the guanine nucleotide exchange factor protein SOS1, increasing the rate at which it catalyzes the exchange of GDP for GTP on its target protein KRAS. While inhibitors of SOS1 have been more widely researched for the treatment of cancer, under some conditions increasing SOS1 activity can also have an…

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3D model (JSmol)
Interactive image
CAS Number
2245237-53-8
Drug class
SOS1 activator
Formula
C26H32ClFN6
Molar mass
483.03 g·mol−1
PubChem CID
134814234

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Overview

Advanced semantic analysis

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Map overview Semantic statistics

VUBI1

Nodes6
Edges5
Triples7
Avg. degree1.67
Density0.333333
Components1

How this topic connects Entity context

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VUBI1

Top relations

3D model (JSmol) · 1
VUBI1 → Interactive image
CAS Number · 1
VUBI1 → 2245237-53-8
Drug class · 1
VUBI1 → SOS1 activator
Formula · 1
VUBI1 → C26H32ClFN6
Molar mass · 1
VUBI1 → 483.03 g·mol−1
PubChem CID · 1
VUBI1 → 134814234
is a · 1
VUBI1 → drug that acts as an activator of the guanine nucleotide exchange factor protein SOS1

Important terminology Word statistics

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Important terminology

sos1 increasing drug activator kras cancer acts guanine nucleotide exchange factor protein rate catalyzes gdp gtp target inhibitors widely researched

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
VUBI13D model (JSmol)Interactive image1.00infobox
VUBI1CAS Number2245237-53-81.00infobox
VUBI1Drug classSOS1 activator1.00infobox
VUBI1FormulaC26H32ClFN61.00infobox
VUBI1Molar mass483.03 g·mol−11.00infobox
VUBI1PubChem CID1348142341.00infobox
VUBI1is adrug that acts as an activator of the guanine nucleotide exchange factor protein SOS10.90text

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