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Smallpox

Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated.

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Causes
variola major virus, variola minor virus (spread between people)
Complications
Scarring of the skin, blindness
Diagnostic method
Based on symptoms and confirmed by PCR
Differential diagnosis
Chickenpox, impetigo, molluscum contagiosum, mpox
Duration
About 4 weeks
Frequency
Eradicated (last naturally occurring case in 1977)

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Mechanism

Diagnosis

Prevention

Treatment

Prognosis

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Smallpox

Nodes402
Edges401
Triples428
Avg. degree2
Density0.004975
Components1

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Smallpox

Top relations

related to Biological warfare · 50
Smallpox → Aboriginal, Aboriginals, According, American Indian, American Revolutionary War, Australia, Australian Studies, Blankets, Bouquet, British, British-held Fort Pitt, Bulletin, Carmody, Christopher Warren, Could, David Day, Delaware, First Fleet, Fort Pitt, Great Lakes
has prevention · 45
Smallpox → According, Accounts, Africa, After, Because, Berkeley, Boston, China, Chinese, Circassia, Circassians, Clopton Havers, Cotton Mather, Cowpox, Dr, Dr Thomas Dimsdale, During, East India Company, Edward Jenner, Empress Catherine
related to Notable cases · 42
Smallpox → Americas, Anne, Aztec, Bavaria, China, Cleves, Cuitláhuac, Date Masamune, Elizabeth, Emperor Komei, England, Famous, For, France, Guru, Guru Har Krishan, Henry VIII, Huayna Capac, Inca, Incan
related to Since eradication · 31
Smallpox → All, Although, Biotechnology VECTOR, Birmingham Medical School, BSL-4, CDC, December, Destroying, Disease Control, Due, Janet Parker, June, Medical School, Parker, Prevention, Russia, Russia's, September, Some, Soviet Union's
related to Eradication · 29
Smallpox → An, Arthur Edmondston, China, Chinese, Clopton Havers, Dr, Dòuzhěn, East India Company, Had, He, His, In China, Johnnie Notions, Lady Mary Wortley Montagu, London, Martin Lister, Notions, People, Pox Rash Teachings, Royal Society
related to Tradition and religion · 26
Smallpox → Among, Brazil, China, Chinese, Dahomean, HIV/AIDS, However, If, In, In China, India, New Year's Eve, Obaluaye, Old World, One, Roughly, Shopona, Sopona, T'ou-Shen Niang-Niang, The
related to External links · 20
Smallpox → Analysis Resource, Archived, BBC Four, BiosecuritySmallpox Images, Center, Diagnosis Synopsis Archived, Extra Life, July, Living Longer, May, PBS, PoxviridaeEpisode, Short History, Smallpox Biosafety, Smallpox Virus StocksDetailed CIDRAP, Vaccines, ViPR, Wayback MachineAgent Fact Sheet, Wayback MachineVirus Pathogen Database, Website About Destruction
related to Disease emergence · 17
Smallpox → At, BCE, CE, China, Egyptian, Hindu, In India, In Japan, India, It, Japan, Ramses, Shitala, Sopona, The, West Africa, Yoruba
related to Research · 17
Smallpox → Atlanta, CDC, In, India, Koltsovo, Most, Research, Russia, The, Two, United States, Vaccinia, Vector Institute, Viral Bioinformatics Resource Center, WHA, WHO, World Health Assembly
related to Evolution · 13
Smallpox → African, American, Asia, Better, If, It, One, Orthopoxvirus, Taterapox, The, This, West Africa, While

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Important terminology

virus disease variola vaccination vaccine hemorrhagic cases form skin first people lesions major early world minor occurred genome may rash

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SmallpoxCausesvariola major virus, variola minor virus (spread between people)1.00infobox
SmallpoxComplicationsScarring of the skin, blindness1.00infobox
SmallpoxDiagnostic methodBased on symptoms and confirmed by PCR1.00infobox
SmallpoxDifferential diagnosisChickenpox, impetigo, molluscum contagiosum, mpox1.00infobox
SmallpoxDurationAbout 4 weeks1.00infobox
SmallpoxFrequencyEradicated (last naturally occurring case in 1977)1.00infobox
SmallpoxMedicationBrincidofovir1.00infobox
SmallpoxOther namesvariola, variola vera, pox, red plague1.00infobox
SmallpoxPreventionSmallpox vaccine1.00infobox
SmallpoxPrognosis30% risk of death1.00infobox
SmallpoxSpecialtyInfectious disease1.00infobox
SmallpoxSymptomsEarly: Fever, vomiting, mouth sores1.00infobox
SmallpoxSymptomsLater: Fluid filled blisters which scab over1.00infobox
SmallpoxTreatmentSupportive care1.00infobox
SmallpoxUsual onset1 to 3 weeks following exposure1.00infobox
Smallpoxis asevere form accompanied by extensive bleeding into the skin0.90text
Smallpoxis aillness with acute onset of fever followed by a rash characterized by firm0.90text

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