Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Urate oxidase: Applications & Standards

In molecular biology, urate oxidase (UO), also known as uricase or factor-independent urate hydroxylase, is a metabolic enzyme found in nearly all species from bacteria to mammals, but is not expressed in humans, great apes, and certain New World monkeys, in which it exists as a pseudogene. It catalyzes the oxidation of uric acid to 5-hydroxyisourate:

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Urate oxidase topic overview

The analysis highlights Applications and Standards as prominent areas in the source structure around Urate oxidase.

Related topics
65
Source areas
10
Connected nodes
75
Extracted relationships
54
Concept neighborhoods
19
Bridge connections
75

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 19 topics
Overview · 11 topics
Convergent evolution · 8 topics
Function · 6 topics
Species distribution · 5 topics
Structure · 5 topics
In legumes · 4 topics
Medical uses · 4 topics
Inhibitors · 2 topics
Localization · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
UOX, UOXP, URICASE, Urate oxidase, urate oxidase (pseudogene)
Band
3 H2|3 72.09 cM
Chr.
Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry
End
146,338,060 bp
Ensembl
ENSG00000240520

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Species distribution

Convergent evolution

Localization

Structure

Function

Inhibitors

Clinical significance

Medical uses

In legumes

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Urate oxidase connects Entity context

The extracted context around Urate oxidase shows recurring relationship patterns in the source. For example, Urate oxidase → According, After, Arg, Gln, HIU, O2, OHCU, Oxygen, The, Urate, Without HIU, X-ray Another extracted example is Urate oxidase → Besides, FAD, HpxO, HpyO, NAD, PuuD, These, UOX, Urate. Use these groups to spot repeated connection types before inspecting the individual relationships.

Urate oxidase

Top relations

related to Function · 12
Urate oxidase → According, After, Arg, Gln, HIU, O2, OHCU, Oxygen, The, Urate, Without HIU, X-ray
related to Convergent evolution · 9
Urate oxidase → Besides, FAD, HpxO, HpyO, NAD, PuuD, These, UOX, Urate
related to Structure · 5
Urate oxidase → It, Sequence, The, UO, Urate
related to Clinical significance · 3
Urate oxidase → Genetically, It, Its
related to Medical uses · 3
Urate oxidase → FDA, PEGylated, Urate
related to Species distribution · 3
Urate oxidase → New World, This, Urate
related to Inhibitors · 2
Urate oxidase → Inhibition, Urate
Aliases · 1
Urate oxidase → UOX, UOXP, URICASE, Urate oxidase, urate oxidase (pseudogene)
Band · 1
Urate oxidase → 3 H2|3 72.09 cM
Chr. · 1
Urate oxidase → Chromosome 3 (mouse)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

urate oxidase acid uric enzyme found humans also bp 5-hydroxyisourate species pseudogene mammals uox mouse uricase chr legumes pathway site

Urate oxidase relationships Subject–Predicate–Object triples

TTTA extracted 54 structured relationships around Urate oxidase. Examples in this analysis include Urate oxidase → Aliases → UOX, UOXP, URICASE, Urate oxidase, urate oxidase (pseudogene) and Urate oxidase → Band → 3 H2|3 72.09 cM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Urate oxidaseAliasesUOX, UOXP, URICASE, Urate oxidase, urate oxidase (pseudogene)1.00infobox
Urate oxidaseBand3 H2|3 72.09 cM1.00infobox
Urate oxidaseChr.Chromosome 3 (mouse)1.00infobox
Urate oxidaseDatabasesNCBI: entry; OMA: entry1.00infobox
Urate oxidaseEnd146,338,060 bp1.00infobox
Urate oxidaseEnsemblENSG000002405201.00infobox
Urate oxidaseEntrez3910511.00infobox
Urate oxidaseExternal IDsMGI: 98907; GeneCards: UOX1.00infobox
Urate oxidaseGene location (Mouse)Gene location (Mouse)Chr.Chromosome 3 (mouse)Band3 H2|3 72.09 cMStart146,276,181 bpEnd146,338,060 bp1.00infobox
Urate oxidaseLocation (UCSC)n/a1.00infobox
Urate oxidaseOrthologsOrthologsDatabasesNCBI: entry; OMA: entrySpeciesHumanMouseEntrez39105122262EnsemblENSG00000240520ENSMUSG00000028186UniProtn aP25688RefSeq (mRNA)n/aNM_009474RefSeq (protein)n/aNP…1.00infobox
Urate oxidaseRefSeq (mRNA)n/a1.00infobox
Urate oxidaseRefSeq (protein)n/a1.00infobox
Urate oxidaseSpeciesHuman1.00infobox
Urate oxidaseUniProtn a1.00infobox
Urate oxidaseis ahomotetrameric enzyme containing four identical active sites situated at the interfaces between its four subunits0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Urate oxidase bring nearby vocabulary together. In this analysis, examples include Urate, Uric and Acid. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Urate oxidase
    • Urate
    • Uric
    • Acid
    • Mouse
    • Patients
    • Pseudogene
    • Species
    • Uox
    • Bp
    • Chr
    • Hiu
    • However
  • urate oxidase
    • Urate
    • Uric
    • Acid
    • Mouse
    • Patients
    • Pseudogene
    • Species
    • Uox
    • Bp
    • Chr
    • Hiu
    • However
  • uric acid
    • Uric
    • Oxidase
    • Pathway
    • Urate
    • Allantoin
    • Hiu
    • However
    • Levels
    • Oxidation
    • 5-hydroxyisourate
    • Also
    • Enzyme
  • amino acid
    • Uric
    • Oxidase
    • Urate
    • Pathway
    • Oxidation
    • Allantoin
    • Hiu
    • However
    • Levels
    • 5-hydroxyisourate
    • Also
    • Enzyme
  • enzyme
    • Pathway
    • Hydroxylase
    • Uo
    • Humans
    • Oxidase
    • Urate
    • Bacteria
    • Molecular
    • Active
    • Allantoin
    • Hiu
    • However
  • bacteria
    • Mammals
    • Pseudogene
    • Species
    • Found
    • Humans
    • Band
    • Hydroxylase
    • Molecular
    • Bp
    • Chr
    • Known
    • Mouse
  • 5-hydroxyisourate
    • Decarboxylase
    • Hydrolase
    • Oxidation
    • Bp
    • Chr
    • Hiu
    • Legumes
    • Mouse
    • Pseudogene
    • Species
    • Uox
    • Uricase
  • mammals
    • Humans
    • Pseudogene
    • Species
    • Band
    • Molecular
    • Bp
    • Chr
    • Levels
    • Many
    • Mouse
    • Protein
    • Uo

Connections between topic areas Semantic bridges

For Urate oxidase, one of the stronger structural bridges in this analysis connects Urate oxidase with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Urate oxidase — Clinical significance · splits 56 ⟂ 20
Urate oxidase — Overview · splits 64 ⟂ 12
Urate oxidase — Convergent evolution · splits 67 ⟂ 9
Urate oxidase — Function · splits 69 ⟂ 7
Urate oxidase — Species distribution · splits 70 ⟂ 6
Urate oxidase — Structure · splits 70 ⟂ 6
Urate oxidase — Medical uses · splits 71 ⟂ 5
Urate oxidase — In legumes · splits 71 ⟂ 5
Urate oxidase — Inhibitors · splits 73 ⟂ 3

Map overview Semantic statistics

Urate oxidase

Nodes76
Edges75
Triples54
Avg. degree1.97
Density0.026316
Components1

Source & methodology

TTTA analyzes the structure around Urate oxidase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Urate oxidase · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.