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UPF1

Regulator of nonsense transcripts 1 (or Up-frameshift suppressor 1 homolog) is a protein that in humans is encoded by the UPF1 gene.

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5.6.2.3
5.6.2.5
Aliases
UPF1, HNORF1, RENT1, pNORF1, smg-2, RNA helicase and ATPase, UPF1 RNA helicase and ATPase, UTF
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GJK, 2GK6, 2GK7, 2IYK, 2WJV, 2WJY, 2XZO, 2XZP
Band
19p13.11 · 8 B3.3|8 34.15 cM
Bgee
right hemisphere of cerebellum · mucosa of transverse colon · olfactory zone of nasal mucosa · granulocyte · skin of leg

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UPF1

Nodes23
Edges22
Triples105
Avg. degree1.91
Density0.086957
Components1

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UPF1

Top relations

Gene ontology · 36
UPF1 → 3'-UTR-mediated mRNA destabilization, ATP binding, cell cycle phase transition, cellular response to interleukin-1, cellular response to lipopolysaccharide, chromatin, chromatin binding, cytoplasm, cytosol, DNA binding, DNA repair, DNA replication, dosage compensation by inactivation of X chromosome, exon-exon junction complex, helicase activity, histone mRNA catabolic process, hydrolase activity, metal ion binding, mRNA export from nucleus, nuclear-transcribed mRNA catabolic process
Bgee · 19
UPF1 → anterior pituitary, aortic valve, ascending aorta, granulocyte, lip, mucosa of transverse colon, muscle of thigh, neural layer of retina, olfactory zone of nasal mucosa, right hemisphere of cerebellum, right lobe of thyroid gland, right testis, right uterine tube, secondary oocyte, skin of leg, spermatocyte, stromal cell of endometrium, ventricular zone, yolk sac
RNA expression pattern · 19
UPF1 → anterior pituitary, aortic valve, ascending aorta, granulocyte, lip, mucosa of transverse colon, muscle of thigh, neural layer of retina, olfactory zone of nasal mucosa, right hemisphere of cerebellum, right lobe of thyroid gland, right testis, right uterine tube, secondary oocyte, skin of leg, spermatocyte, stromal cell of endometrium, ventricular zone, yolk sac
related to Interactions · 5
UPF1 → DCP1A, DCP2, SMG1, UPF2, UPF3A
Band · 2
UPF1 → 19p13.11, 8 B3.3|8 34.15 cM
Chr. · 2
UPF1 → Chromosome 19 (human), Chromosome 8 (mouse)
End · 2
UPF1 → 18,868,230 bp, 70,805,928 bp
5.6.2.3 · 1
UPF1 → ↗
5.6.2.5 · 1
UPF1 → ↗
Aliases · 1
UPF1 → UPF1, HNORF1, RENT1, pNORF1, smg-2, RNA helicase and ATPase, UPF1 RNA helicase and ATPase, UTF

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Important terminology

bp gene chr human band chromosome 19 protein mrna location mouse junction function cytoplasm nucleus homolog rna helicase search activity

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
UPF15.6.2.31.00infobox
UPF15.6.2.51.00infobox
UPF1AliasesUPF1, HNORF1, RENT1, pNORF1, smg-2, RNA helicase and ATPase, UPF1 RNA helicase and ATPase, UTF1.00infobox
UPF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GJK, 2GK6, 2GK7, 2IYK, 2WJV, 2WJY, 2XZO, 2XZP1.00infobox
UPF1Band19p13.111.00infobox
UPF1Band8 B3.3|8 34.15 cM1.00infobox
UPF1Bgeeright hemisphere of cerebellum1.00infobox
UPF1Bgeemucosa of transverse colon1.00infobox
UPF1Bgeeolfactory zone of nasal mucosa1.00infobox
UPF1Bgeegranulocyte1.00infobox
UPF1Bgeeskin of leg1.00infobox
UPF1Bgeeanterior pituitary1.00infobox
UPF1Bgeeright uterine tube1.00infobox
UPF1Bgeeright testis1.00infobox
UPF1Bgeeright lobe of thyroid gland1.00infobox
UPF1Bgeestromal cell of endometrium1.00infobox
UPF1Bgeespermatocyte1.00infobox
UPF1Bgeeaortic valve1.00infobox
UPF1Bgeelip1.00infobox
UPF1Bgeeascending aorta1.00infobox
UPF1Bgeesecondary oocyte1.00infobox
UPF1Bgeeventricular zone1.00infobox
UPF1Bgeeyolk sac1.00infobox
UPF1Bgeemuscle of thigh1.00infobox
UPF1Bgeeneural layer of retina1.00infobox
UPF1BioGPSMore reference expression data1.00infobox
UPF1Chr.Chromosome 19 (human)1.00infobox
UPF1Chr.Chromosome 8 (mouse)1.00infobox
UPF1DatabasesNCBI: entry; OMA: entry1.00infobox
UPF1End18,868,230 bp1.00infobox

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