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UBQLN2

Ubiquilin-2 is a protein that in humans is encoded by the UBQLN2 gene.

Function, Interactions & Similarity to other proteins

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Function

9 related topics

Interactions

3 related topics

Similarity to other proteins

2 related topics

Clinical significance

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
UBQLN2, ALS15, CHAP1, DSK2, N4BP4, PLIC2, HRIHFB2157, ubiquilin 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1J8C
Band
Xp11.21 · X|X F3
Bgee
cerebellar vermis · pons · postcentral gyrus · endothelial cell · Brodmann area 23
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

Topics to explore

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Overview

Function

Similarity to other proteins

Clinical significance

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

UBQLN2

Nodes24
Edges23
Triples91
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

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UBQLN2

Top relations

Bgee · 19
UBQLN2 → anterior amygdaloid area, arcuate nucleus, Brodmann area 23, cerebellar vermis, dorsomedial hypothalamic nucleus, endothelial cell, entorhinal cortex, habenula, median eminence, middle temporal gyrus, paraventricular nucleus of hypothalamus, pons, postcentral gyrus, retinal pigment epithelium, seminal vesicula, subiculum, superior vestibular nucleus, ventral tegmental area, ventromedial nucleus
RNA expression pattern · 19
UBQLN2 → anterior amygdaloid area, arcuate nucleus, Brodmann area 23, cerebellar vermis, dorsomedial hypothalamic nucleus, endothelial cell, entorhinal cortex, habenula, median eminence, middle temporal gyrus, paraventricular nucleus of hypothalamus, pons, postcentral gyrus, retinal pigment epithelium, seminal vesicula, subiculum, superior vestibular nucleus, ventral tegmental area, ventromedial nucleus
Gene ontology · 18
UBQLN2 → autophagosome, autophagosome assembly, autophagy, cytoplasm, cytoplasmic vesicle, cytosol, membrane, negative regulation of clathrin-dependent endocytosis, negative regulation of G protein-coupled receptor internalization, nucleus, plasma membrane, polyubiquitin modification-dependent protein binding, positive regulation of ER-associated ubiquitin-dependent protein catabolic process, protein binding, regulation of autophagosome assembly, regulation of macroautophagy, ubiquitin-dependent ERAD pathway, ubiquitin-dependent protein catabolic process
related to Clinical significance · 7
UBQLN2 → ALS, C9ORF72, In, TDP-43, The, This, Ubiquilin
related to Similarity to other proteins · 3
UBQLN2 → Human UBQLN2, UBQLN1, UBQLN4
Band · 2
UBQLN2 → Xp11.21, X|X F3
Chr. · 2
UBQLN2 → X chromosome (human), X chromosome (mouse)
End · 2
UBQLN2 → 152,284,566 bp, 56,567,868 bp
related to Interactions · 2
UBQLN2 → HERPUD1, UBE3A
Aliases · 1
UBQLN2 → UBQLN2, ALS15, CHAP1, DSK2, N4BP4, PLIC2, HRIHFB2157, ubiquilin 2

Important terminology Word statistics

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Important terminology

bp gene human chr band protein ubiquilin chromosome location similarity mouse function search 567 868 end 56 284 566 proteins

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
UBQLN2AliasesUBQLN2, ALS15, CHAP1, DSK2, N4BP4, PLIC2, HRIHFB2157, ubiquilin 21.00infobox
UBQLN2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1J8C1.00infobox
UBQLN2BandXp11.211.00infobox
UBQLN2BandX|X F31.00infobox
UBQLN2Bgeecerebellar vermis1.00infobox
UBQLN2Bgeepons1.00infobox
UBQLN2Bgeepostcentral gyrus1.00infobox
UBQLN2Bgeeendothelial cell1.00infobox
UBQLN2BgeeBrodmann area 231.00infobox
UBQLN2Bgeeretinal pigment epithelium1.00infobox
UBQLN2Bgeeentorhinal cortex1.00infobox
UBQLN2Bgeesuperior vestibular nucleus1.00infobox
UBQLN2Bgeeseminal vesicula1.00infobox
UBQLN2Bgeemiddle temporal gyrus1.00infobox
UBQLN2Bgeehabenula1.00infobox
UBQLN2Bgeeventral tegmental area1.00infobox
UBQLN2Bgeearcuate nucleus1.00infobox
UBQLN2Bgeemedian eminence1.00infobox
UBQLN2Bgeesubiculum1.00infobox
UBQLN2Bgeeparaventricular nucleus of hypothalamus1.00infobox
UBQLN2Bgeeanterior amygdaloid area1.00infobox
UBQLN2Bgeeventromedial nucleus1.00infobox
UBQLN2Bgeedorsomedial hypothalamic nucleus1.00infobox
UBQLN2BioGPSMore reference expression data1.00infobox
UBQLN2Chr.X chromosome (human)1.00infobox
UBQLN2Chr.X chromosome (mouse)1.00infobox
UBQLN2DatabasesNCBI: entry; OMA: entry1.00infobox
UBQLN2End56,567,868 bp1.00infobox
UBQLN2End152,284,566 bp1.00infobox
UBQLN2EnsemblENSG000001880211.00infobox

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