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TRPC4: Function, Tissue distribution & Interactions

The short transient receptor potential channel 4 (TrpC4), also known as Trp-related protein 4, is a protein that in humans is encoded by the TRPC4 gene.

Language: English [EN]
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TRPC4 topic overview

The analysis highlights Function, Tissue distribution and Interactions as prominent areas in the source structure around TRPC4.

Related topics
21
Source areas
5
Connected nodes
26
Extracted relationships
107
Concept neighborhoods
8
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 7 topics
Tissue distribution · 5 topics
Interactions · 4 topics
Clinical significance · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TRPC4, HTRP-4, HTRP4, TRP4, transient receptor potential cation channel subfamily C member 4
Band
13q13.3 · 3 C|3 25.43 cM
Bgee
stromal cell of endometrium · decidua · smooth muscle tissue · testicle · body of uterus
BioGPS
More reference expression data
Chr.
Chromosome 13 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Tissue distribution

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TRPC4 connects Entity context

The extracted context around TRPC4 shows recurring relationship patterns in the source. For example, TRPC4 → basolateral plasma membrane, beta-catenin binding, cadherin binding, calcium channel activity, calcium channel complex, calcium ion import, calcium ion transmembrane transport, calcium ion transport, cation channel complex, caveola, cell surface, cell-cell junction, cortical cytoskeleton, gamma-aminobutyric acid secretion, inositol 1,4,5 trisphosphate binding, integral component of membrane, integral component of plasma membrane, ion channel activity, ion transport, manganese ion transport Another extracted example is TRPC4 → anterior amygdaloid area, barrel cortex, body of uterus, CA3 field, decidua, dentate gyrus, dentate gyrus of hippocampal formation granule cell, gallbladder, hippocampus proper, lateral septal nucleus, left coronary artery, myometrium, prostate, Region I of hippocampus proper, right coronary artery, secondary oocyte, smooth muscle tissue, stromal cell of endometrium, subiculum, testicle. Use these groups to spot repeated connection types before inspecting the individual relationships.

TRPC4

Top relations

Gene ontology · 29
TRPC4 → basolateral plasma membrane, beta-catenin binding, cadherin binding, calcium channel activity, calcium channel complex, calcium ion import, calcium ion transmembrane transport, calcium ion transport, cation channel complex, caveola, cell surface, cell-cell junction, cortical cytoskeleton, gamma-aminobutyric acid secretion, inositol 1,4,5 trisphosphate binding, integral component of membrane, integral component of plasma membrane, ion channel activity, ion transport, manganese ion transport
Bgee · 20
TRPC4 → anterior amygdaloid area, barrel cortex, body of uterus, CA3 field, decidua, dentate gyrus, dentate gyrus of hippocampal formation granule cell, gallbladder, hippocampus proper, lateral septal nucleus, left coronary artery, myometrium, prostate, Region I of hippocampus proper, right coronary artery, secondary oocyte, smooth muscle tissue, stromal cell of endometrium, subiculum, testicle
RNA expression pattern · 20
TRPC4 → anterior amygdaloid area, barrel cortex, body of uterus, CA3 field, decidua, dentate gyrus, dentate gyrus of hippocampal formation granule cell, gallbladder, hippocampus proper, lateral septal nucleus, left coronary artery, myometrium, prostate, Region I of hippocampus proper, right coronary artery, secondary oocyte, smooth muscle tissue, stromal cell of endometrium, subiculum, testicle
related to External links · 6
TRPC4 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
related to Roles · 4
TRPC4 → Deletion, Given, However, These
related to Function · 3
TRPC4 → Gαi-coupled, Gαq-coupled, This
related to Interactions · 3
TRPC4 → ITPR1, TRPC1, TRPC5
Band · 2
TRPC4 → 13q13.3, 3 C|3 25.43 cM
Chr. · 2
TRPC4 → Chromosome 13 (human), Chromosome 3 (mouse)
End · 2
TRPC4 → 37,869,802 bp, 54,225,892 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp human chr band channel cation chromosome 13 protein transient receptor potential location also mouse function tissue external role

TRPC4 relationships Subject–Predicate–Object triples

TTTA extracted 107 structured relationships around TRPC4. Examples in this analysis include TRPC4 → Aliases → TRPC4, HTRP-4, HTRP4, TRP4, transient receptor potential cation channel subfamily C member 4 and TRPC4 → Band → 13q13.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TRPC4AliasesTRPC4, HTRP-4, HTRP4, TRP4, transient receptor potential cation channel subfamily C member 41.00infobox
TRPC4Band13q13.31.00infobox
TRPC4Band3 C|3 25.43 cM1.00infobox
TRPC4Bgeestromal cell of endometrium1.00infobox
TRPC4Bgeedecidua1.00infobox
TRPC4Bgeesmooth muscle tissue1.00infobox
TRPC4Bgeetesticle1.00infobox
TRPC4Bgeebody of uterus1.00infobox
TRPC4Bgeeright coronary artery1.00infobox
TRPC4Bgeemyometrium1.00infobox
TRPC4Bgeeleft coronary artery1.00infobox
TRPC4Bgeeprostate1.00infobox
TRPC4Bgeegallbladder1.00infobox
TRPC4Bgeelateral septal nucleus1.00infobox
TRPC4Bgeesubiculum1.00infobox
TRPC4BgeeRegion I of hippocampus proper1.00infobox
TRPC4BgeeCA3 field1.00infobox
TRPC4Bgeedentate gyrus1.00infobox
TRPC4Bgeeanterior amygdaloid area1.00infobox
TRPC4Bgeehippocampus proper1.00infobox
TRPC4Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
TRPC4Bgeebarrel cortex1.00infobox
TRPC4Bgeesecondary oocyte1.00infobox
TRPC4BioGPSMore reference expression data1.00infobox
TRPC4Chr.Chromosome 13 (human)1.00infobox
TRPC4Chr.Chromosome 3 (mouse)1.00infobox
TRPC4DatabasesNCBI: entry; OMA: entry1.00infobox
TRPC4End37,869,802 bp1.00infobox
TRPC4End54,225,892 bp1.00infobox
TRPC4EnsemblENSG000001331071.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TRPC4 bring nearby vocabulary together. In this analysis, examples include Gene, Channel and Potential. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • TRPC4
    • Gene
    • Channel
    • Potential
    • Receptor
    • Transient
    • Cation
    • Protein
    • Human
    • Also
    • Area
    • Complex
    • Expressed
  • trpc4
    • Gene
    • Channel
    • Potential
    • Receptor
    • Transient
    • Cation
    • Protein
    • Human
    • Also
    • Area
    • Complex
    • Expressed
  • protein
    • Cell
    • Receptor
    • Transient
    • Cation
    • Human
    • Trpc4
    • Area
    • Complex
    • End
    • Expressed
    • Function
    • Gene
  • gene
    • Trpc4
    • Location
    • Potential
    • Receptor
    • Transient
    • Chromosome
    • Bp
    • Chr
    • Human
    • Complex
    • End
    • Expressed
  • transient receptor potential cation channels
    • Potential
    • Receptor
    • Transient
    • Channel
    • Also
    • Function
    • Member
    • Tissue
    • Cell
    • Location
    • Cation
    • Chromosome
  • ventral tegmental area
    • Mrna
    • Cell
    • Complex
    • End
    • Expressed
    • Function
    • Member
    • Mouse
    • Tissue
    • Location
    • Potential
    • Receptor
  • function
    • Member
    • Tissue
    • Location
    • Potential
    • Receptor
    • Transient
    • Cation
    • Chromosome
    • External
    • Bp
    • Chr
    • Human
  • tissue distribution
    • Member
    • Location
    • Transient
    • Human
    • Area
    • Cell
    • Complex
    • End
    • Expressed
    • Mouse
    • Mrna
    • Band

Connections between topic areas Semantic bridges

For TRPC4, one of the stronger structural bridges in this analysis connects TRPC4 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TRPC4Function · splits 19 ⟂ 8
TRPC4Tissue distribution · splits 21 ⟂ 6
TRPC4Interactions · splits 22 ⟂ 5
TRPC4Clinical significance · splits 23 ⟂ 4
TRPC4Overview · splits 24 ⟂ 3

Map overview Semantic statistics

TRPC4

Nodes27
Edges26
Triples107
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around TRPC4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Tissue distribution & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TRPC4 · EN edition · Analysis: TopicsToTalkAbout

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