Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

TGF beta 1

Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene.

Function, Interactions & Overview

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around TGF beta 1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KLA, 1KLC, 1KLD, 3KFD, 4KV5
Band
19q13.2 · 7 A3|7 13.98 cM
Bgee
granulocyte · monocyte · stromal cell of endometrium · ascending aorta · Descending thoracic aorta
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

TGF beta 1

Nodes56
Edges55
Triples288
Avg. degree1.96
Density0.035714
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

TGF beta 1

Top relations

Gene ontology · 226
TGF beta 1 → adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ageing, animal organ regeneration, antigen binding, apoptotic process, ATP biosynthetic process, axon, blood microparticle, BMP signaling pathway, branch elongation involved in mammary gland duct branching, cell activation, cell development, cell growth, cell migration, cell population proliferation, cell surface, cell-cell junction organization, cellular calcium ion homeostasis, cellular response to dexamethasone stimulus, cellular response to growth factor stimulus
Bgee · 18
TGF beta 1 → ascending aorta, blood, body of femur, calvaria, canal of the cervix, Descending thoracic aorta, granulocyte, lower jaw, mesenteric lymph nodes, molar, monocyte, right coronary artery, right lung, spleen, stroma of bone marrow, stromal cell of endometrium, thymus, tibiofemoral joint
RNA expression pattern · 18
TGF beta 1 → ascending aorta, blood, body of femur, calvaria, canal of the cervix, Descending thoracic aorta, granulocyte, lower jaw, mesenteric lymph nodes, molar, monocyte, right coronary artery, right lung, spleen, stroma of bone marrow, stromal cell of endometrium, thymus, tibiofemoral joint
related to Interactions · 3
TGF beta 1 → Decorin, EIF3ILTBP1, TGF
Band · 2
TGF beta 1 → 19q13.2, 7 A3|7 13.98 cM
Chr. · 2
TGF beta 1 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
TGF beta 1 → 25,404,502 bp, 41,353,922 bp
Aliases · 1
TGF beta 1 → TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta1
Available structures · 1
TGF beta 1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KLA, 1KLC, 1KLD, 3KFD, 4KV5
BioGPS · 1
TGF beta 1 → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

tgf-β1 cells proliferation growth bp cell human chr band transforming factor gene differentiation cytokines beta chromosome 19 tgfb1 expression immune

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TGF beta 1AliasesTGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta11.00infobox
TGF beta 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KLA, 1KLC, 1KLD, 3KFD, 4KV51.00infobox
TGF beta 1Band19q13.21.00infobox
TGF beta 1Band7 A3|7 13.98 cM1.00infobox
TGF beta 1Bgeegranulocyte1.00infobox
TGF beta 1Bgeemonocyte1.00infobox
TGF beta 1Bgeestromal cell of endometrium1.00infobox
TGF beta 1Bgeeascending aorta1.00infobox
TGF beta 1BgeeDescending thoracic aorta1.00infobox
TGF beta 1Bgeeright coronary artery1.00infobox
TGF beta 1Bgeespleen1.00infobox
TGF beta 1Bgeeright lung1.00infobox
TGF beta 1Bgeecanal of the cervix1.00infobox
TGF beta 1Bgeeblood1.00infobox
TGF beta 1Bgeemolar1.00infobox
TGF beta 1Bgeetibiofemoral joint1.00infobox
TGF beta 1Bgeestroma of bone marrow1.00infobox
TGF beta 1Bgeecalvaria1.00infobox
TGF beta 1Bgeemesenteric lymph nodes1.00infobox
TGF beta 1Bgeelower jaw1.00infobox
TGF beta 1Bgeethymus1.00infobox
TGF beta 1Bgeebody of femur1.00infobox
TGF beta 1BioGPSMore reference expression data1.00infobox
TGF beta 1Chr.Chromosome 19 (human)1.00infobox
TGF beta 1Chr.Chromosome 7 (mouse)1.00infobox
TGF beta 1DatabasesNCBI: entry; OMA: entry1.00infobox
TGF beta 1End41,353,922 bp1.00infobox
TGF beta 1End25,404,502 bp1.00infobox
TGF beta 1EnsemblENSG000001053291.00infobox
TGF beta 1Entrez70401.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.