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Tenascin X: Function, Gene & Clinical significance

Tenascin X (TN-X), also known as flexillin or hexabrachion-like protein, is a 450 kDa glycoprotein, a member of the tenascin family, that is expressed in connective tissues. In humans it is encoded by the TNXB gene.

Language: English [EN]
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Tenascin X topic overview

The analysis highlights Function, Gene and Clinical significance as prominent areas in the source structure around Tenascin X.

Related topics
52
Source areas
5
Connected nodes
57
Extracted relationships
93
Concept neighborhoods
16
Bridge connections
57

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 34 topics
Gene · 9 topics
Overview · 4 topics
Clinical significance · 3 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS, tenascin XB, EDSCLL, EDSCLL1
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2CUH, 2CUI, 2CUM
Band
6p21.33-p21.32 · 17 B1|17 18.24 cM
Bgee
apex of heart · right adrenal cortex · left adrenal gland · left adrenal cortex · gastric mucosa
BioGPS
n/a
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Gene

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Tenascin X connects Entity context

The extracted context around Tenascin X shows recurring relationship patterns in the source. For example, Tenascin X → ankle, ankle joint, apex of heart, body of uterus, extensor digitorum longus muscle, extraocular muscle, gastric mucosa, lactiferous gland, left adrenal cortex, left adrenal gland, left ovary, medial head of gastrocnemius muscle, myometrium, plantaris muscle, right adrenal cortex, right auricle of heart, sciatic nerve, skin of external ear, tibial nerve, tunica media of zone of aorta Another extracted example is Tenascin X → actin cytoskeleton organization, cell adhesion, collagen fibril binding, collagen fibril organization, collagen metabolic process, collagen-containing extracellular matrix, elastic fiber assembly, extracellular exosome, extracellular matrix, extracellular matrix organization, extracellular matrix structural constituent, extracellular region, extracellular space, fibrillar collagen trimer, heparin binding, integrin binding, intracellular anatomical structure, protein binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

Tenascin X

Top relations

Bgee · 20
Tenascin X → ankle, ankle joint, apex of heart, body of uterus, extensor digitorum longus muscle, extraocular muscle, gastric mucosa, lactiferous gland, left adrenal cortex, left adrenal gland, left ovary, medial head of gastrocnemius muscle, myometrium, plantaris muscle, right adrenal cortex, right auricle of heart, sciatic nerve, skin of external ear, tibial nerve, tunica media of zone of aorta
RNA expression pattern · 20
Tenascin X → ankle, ankle joint, apex of heart, body of uterus, extensor digitorum longus muscle, extraocular muscle, gastric mucosa, lactiferous gland, left adrenal cortex, left adrenal gland, left ovary, medial head of gastrocnemius muscle, myometrium, plantaris muscle, right adrenal cortex, right auricle of heart, sciatic nerve, skin of external ear, tibial nerve, tunica media of zone of aorta
Gene ontology · 18
Tenascin X → actin cytoskeleton organization, cell adhesion, collagen fibril binding, collagen fibril organization, collagen metabolic process, collagen-containing extracellular matrix, elastic fiber assembly, extracellular exosome, extracellular matrix, extracellular matrix organization, extracellular matrix structural constituent, extracellular region, extracellular space, fibrillar collagen trimer, heparin binding, integrin binding, intracellular anatomical structure, protein binding
Band · 2
Tenascin X → 17 B1|17 18.24 cM, 6p21.33-p21.32
Chr. · 2
Tenascin X → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
Tenascin X → 32,115,334 bp, 34,938,789 bp
Aliases · 1
Tenascin X → TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS, tenascin XB, EDSCLL, EDSCLL1
Available structures · 1
Tenascin X → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2CUH, 2CUI, 2CUM
BioGPS · 1
Tenascin X → n/a
Databases · 1
Tenascin X → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

tn-x gene tnxb human protein skin bp collagen chr band chromosome expressed structure function tenascin tnxa external location iii also

Tenascin X relationships Subject–Predicate–Object triples

TTTA extracted 93 structured relationships around Tenascin X. Examples in this analysis include Tenascin X → Aliases → TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS, tenascin XB, EDSCLL, EDSCLL1 and Tenascin X → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2CUH, 2CUI, 2CUM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Tenascin XAliasesTNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS, tenascin XB, EDSCLL, EDSCLL11.00infobox
Tenascin XAvailable structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2CUH, 2CUI, 2CUM1.00infobox
Tenascin XBand6p21.33-p21.321.00infobox
Tenascin XBand17 B1|17 18.24 cM1.00infobox
Tenascin XBgeeapex of heart1.00infobox
Tenascin XBgeeright adrenal cortex1.00infobox
Tenascin XBgeeleft adrenal gland1.00infobox
Tenascin XBgeeleft adrenal cortex1.00infobox
Tenascin XBgeegastric mucosa1.00infobox
Tenascin XBgeeright auricle of heart1.00infobox
Tenascin XBgeebody of uterus1.00infobox
Tenascin XBgeeleft ovary1.00infobox
Tenascin XBgeemyometrium1.00infobox
Tenascin XBgeetibial nerve1.00infobox
Tenascin XBgeeankle joint1.00infobox
Tenascin XBgeeankle1.00infobox
Tenascin XBgeeextraocular muscle1.00infobox
Tenascin XBgeesciatic nerve1.00infobox
Tenascin XBgeetunica media of zone of aorta1.00infobox
Tenascin XBgeeplantaris muscle1.00infobox
Tenascin XBgeeextensor digitorum longus muscle1.00infobox
Tenascin XBgeelactiferous gland1.00infobox
Tenascin XBgeeskin of external ear1.00infobox
Tenascin XBgeemedial head of gastrocnemius muscle1.00infobox
Tenascin XBioGPSn/a1.00infobox
Tenascin XChr.Chromosome 6 (human)1.00infobox
Tenascin XChr.Chromosome 17 (mouse)1.00infobox
Tenascin XDatabasesNCBI: entry; OMA: entry1.00infobox
Tenascin XEnd32,115,334 bp1.00infobox
Tenascin XEnd34,938,789 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Tenascin X bring nearby vocabulary together. In this analysis, examples include Uniprot, External and Expressed. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Tenascin X
    • Uniprot
    • External
    • Expressed
    • Location
    • Structure
    • Bp
    • Chr
    • Chromosome
    • Function
    • Gene
    • Tn-x
    • Human
  • tenascin x
    • Uniprot
    • External
    • Expressed
    • Location
    • Structure
    • Bp
    • Chr
    • Chromosome
    • Function
    • Gene
    • Tn-x
    • Human
  • tenascin
    • Uniprot
    • External
    • Expressed
    • Location
    • Structure
    • Bp
    • Chr
    • Chromosome
    • Function
    • Gene
    • Tn-x
    • Human
  • gene
    • Structure
    • Tnxb
    • Chromosome
    • Location
    • Tenascin
    • Bp
    • Chr
    • Function
    • Human
    • Functional
    • Mouse
    • Uniprot
  • skin
    • Blood
    • Vessels
    • Tn-x
    • Kidneys
    • External
    • Tendons
    • Tissue
    • Within
    • Function
    • Collagen
    • Mouse
    • Uniprot
  • function
    • Uniprot
    • External
    • Human
    • Tn-x
    • Location
    • Structure
    • Tenascin
    • Bp
    • Chr
    • Chromosome
    • Gene
    • Skin
  • structure
    • Functional
    • Uniprot
    • External
    • Genes
    • Location
    • Tenascin
    • Bp
    • Chr
    • Chromosome
    • Function
    • Mouse
    • Tnxb
  • connective tissue
    • Tissue
    • Tn-x
    • Protein
    • Haploinsufficiency
    • Blood
    • Eds
    • External
    • Syndrome
    • Tendons
    • Tissues
    • Tnx
    • Vessels

Connections between topic areas Semantic bridges

For Tenascin X, one of the stronger structural bridges in this analysis connects Tenascin X with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Tenascin XFunction · splits 23 ⟂ 35
Tenascin XGene · splits 48 ⟂ 10
Tenascin XOverview · splits 53 ⟂ 5
Tenascin XClinical significance · splits 54 ⟂ 4
Tenascin XStructure · splits 55 ⟂ 3

Map overview Semantic statistics

Tenascin X

Nodes58
Edges57
Triples93
Avg. degree1.97
Density0.034483
Components1

Source & methodology

TTTA analyzes the structure around Tenascin X to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Gene & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Tenascin X · EN edition · Analysis: TopicsToTalkAbout

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