Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Telithromycin: History & Measurement

Telithromycin is the first ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek. It is used to treat community acquired pneumonia of mild to moderate severity. After significant safety concerns, the US Food and Drug Administration sharply curtailed the approved uses of the drug in early 2007.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Telithromycin topic overview

The analysis highlights History and Measurement as prominent areas in the source structure around Telithromycin.

Related topics
26
Source areas
5
Connected nodes
31
Extracted relationships
75
Concept neighborhoods
13
Bridge connections
31

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics
History · 7 topics
Mechanism of action · 5 topics
Adverse effects · 4 topics
Pharmacokinetics · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01FA15 (WHO)
Bioavailability
57%
CAS Number
191114-48-4 Y
ChEBI
CHEBI:29688

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Adverse effects

Mechanism of action

Pharmacokinetics

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Telithromycin connects Entity context

The extracted context around Telithromycin shows recurring relationship patterns in the source. For example, Telithromycin → April, Drug Administration, European Commission, FDA, Food, French, HMR-3647, Hoechst Marion Roussel, II/III, In, July, October, Sanofi-Aventis, US Another extracted example is Telithromycin → Annals, Article, FDA Public Health Advisory, Internal Medicine, Ketek, KETEK Oral, Ketek'Drugs, Login, Patient Handout, Treatments, WebMD, York Times. Use these groups to spot repeated connection types before inspecting the individual relationships.

Telithromycin

Top relations

related to history · 14
Telithromycin → April, Drug Administration, European Commission, FDA, Food, French, HMR-3647, Hoechst Marion Roussel, II/III, In, July, October, Sanofi-Aventis, US
related to External links · 12
Telithromycin → Annals, Article, FDA Public Health Advisory, Internal Medicine, Ketek, KETEK Oral, Ketek'Drugs, Login, Patient Handout, Treatments, WebMD, York Times
has effect · 7
Telithromycin → Headache, Less, March, Most, Prolonged QTc, Rare, Three
related to Pharmacokinetics · 7
Telithromycin → Due, During, It, L-cladinose, Streptococcus, The, Unlike
related to Mechanism of action · 3
Telithromycin → In, Like, RNA
Legal status · 2
Telithromycin → UK: POM (Prescription only), US: ℞-only
is a · 2
Telithromycin → first ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek, semi-synthetic erythromycin derivative
related to Metabolism · 2
Telithromycin → About, Telithromycin's
3D model (JSmol) · 1
Telithromycin → Interactive image
AHFS/Drugs.com · 1
Telithromycin → Monograph

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fda ketek liver safety 2006 approval approved sanofi-aventis also one cases patients clinical drug ring carbamate data us administration antibiotic

Telithromycin relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around Telithromycin. Examples in this analysis include Telithromycin → 3D model (JSmol) → Interactive image and Telithromycin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Telithromycin3D model (JSmol)Interactive image1.00infobox
TelithromycinAHFS/Drugs.comMonograph1.00infobox
TelithromycinATC codeJ01FA15 (WHO)1.00infobox
TelithromycinBioavailability57%1.00infobox
TelithromycinCAS Number191114-48-4 Y1.00infobox
TelithromycinChEBICHEBI:296881.00infobox
TelithromycinChEMBLChEMBL1136 Y1.00infobox
TelithromycinChemSpider2273373 Y1.00infobox
TelithromycinCompTox Dashboard (EPA)DTXSID30464551.00infobox
TelithromycinDrugBankDB00976 Y1.00infobox
TelithromycinECHA InfoCard100.208.2061.00infobox
TelithromycinElimination half-life10 hours1.00infobox
TelithromycinExcretionBiliary and renal1.00infobox
TelithromycinFormulaC43H65N5O101.00infobox
TelithromycinKEGGD01078 N1.00infobox
TelithromycinLegal statusUK: POM (Prescription only)1.00infobox
TelithromycinLegal statusUS: ℞-only1.00infobox
TelithromycinLicense dataEU EMA: by INN1.00infobox
TelithromycinMedlinePlusa6040261.00infobox
TelithromycinMelting point177 °C (351 °F)1.00infobox
TelithromycinMetabolismHepatic (50% CYP3A4-mediated)1.00infobox
TelithromycinMolar mass812.018 g·mol−11.00infobox
TelithromycinProtein binding66% to 79%1.00infobox
TelithromycinPubChem CID54625161.00infobox
TelithromycinRoutes of administrationOral1.00infobox
TelithromycinTrade namesKetek, others1.00infobox
TelithromycinUNIIKI8H7H19WL1.00infobox
Telithromycinis afirst ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek0.90text
Telithromycinis asemi-synthetic erythromycin derivative0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Telithromycin bring nearby vocabulary together. In this analysis, examples include Liver, 50s and Erythromycin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Telithromycin
    • Liver
    • 50s
    • Erythromycin
    • Protein
    • Times
    • Also
    • Cases
    • Ketek
    • Fda
    • Name
    • Drugs
    • Us
  • telithromycin
    • Liver
    • 50s
    • Erythromycin
    • Protein
    • Times
    • Also
    • Cases
    • Ketek
    • Fda
    • Name
    • Drugs
    • Us
  • food and drug administration
    • Administration
    • Food
    • Us
    • Drug
    • Metabolism
    • Safety
    • Approval
    • Name
    • Drugs
    • Protein
    • Warning
    • Approved
  • black box warning
    • Metabolism
    • Name
    • Administration
    • Drugs
    • Protein
    • Us
    • Data
    • Fda
    • Including
    • States
    • Patients
    • Safety
  • antibiotic
    • Ketek
    • Name
    • Use
    • Drugs
    • Clinical
    • Failure
    • Including
    • Safety
    • Liver
    • Fda
    • Telithromycin
  • clinical trials
    • Sanofi-aventis
    • Patients
    • Ketek
    • Name
    • Use
    • Data
    • Study
    • One
    • Approval
    • Telithromycin
    • Fda
  • liver transplant
    • Failure
    • Cases
    • One
    • Telithromycin
    • Moiety
    • States
    • Study
    • Patients
  • protein synthesis
    • 50s
    • Us
    • Warning
    • Also
    • Safety
    • Telithromycin

Connections between topic areas Semantic bridges

For Telithromycin, one of the stronger structural bridges in this analysis connects Telithromycin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Telithromycin — Overview · splits 22 ⟂ 10
Telithromycin — History · splits 24 ⟂ 8
Telithromycin — Mechanism of action · splits 26 ⟂ 6
Telithromycin — Adverse effects · splits 27 ⟂ 5

Map overview Semantic statistics

Telithromycin

Nodes32
Edges31
Triples75
Avg. degree1.94
Density0.0625
Components1

Source & methodology

TTTA analyzes the structure around Telithromycin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Telithromycin · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.