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SYT1

Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene.

Interactions, Function & Clinical Significance

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Interactions

4 related topics

Function

3 related topics

Clinical Significance

2 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
SYT1, P65, SVP65, SYT, synaptotagmin 1, BAGOS
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2K45, 2K4A, 2K8M, 2KI6, 2LHA, 2N1T, 2R83, 3F00, 3F01, 3F04, 3F05, 4ISQ, 4V11
Band
12q21.2 · 10 D1|10 56.52 cM
Bgee
middle temporal gyrus · Brodmann area 23 · endothelial cell · lateral nuclear group of thalamus · orbitofrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 10 (mouse)

Topics to explore

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Overview

Function

Interactions

Clinical Significance

Advanced semantic analysis

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Map overview Semantic statistics

SYT1

Nodes16
Edges15
Triples158
Avg. degree1.88
Density0.125
Components1

How this topic connects Entity context

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SYT1

Top relations

Gene ontology · 84
SYT1 → 1-phosphatidylinositol binding, axon, brain development, calcium ion binding, calcium ion sensor activity, calcium ion-regulated exocytosis of neurotransmitter, calcium-dependent activation of synaptic vesicle fusion, calcium-dependent phospholipid binding, calcium-dependent protein binding, calcium-ion regulated exocytosis, calmodulin binding, cell differentiation, cell junction, cellular response to calcium ion, chemical synaptic transmission, chromaffin granule membrane, clathrin binding, clathrin-coated vesicle membrane, clathrin-sculpted acetylcholine transport vesicle membrane, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
Bgee · 19
SYT1 → Brodmann area 10, Brodmann area 23, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, endothelial cell, frontal pole, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, neural layer of retina, orbitofrontal cortex, pons, primary motor cortex, primary visual cortex, subiculum, superior frontal gyrus
RNA expression pattern · 19
SYT1 → Brodmann area 10, Brodmann area 23, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, endothelial cell, frontal pole, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, neural layer of retina, orbitofrontal cortex, pons, primary motor cortex, primary visual cortex, subiculum, superior frontal gyrus
related to Function · 6
SYT1 → Ca2, Calcium, OMIM, SNARE, Supplied, Synaptotagmins
related to Clinical Significance · 3
SYT1 → Baker-Gordon Syndrome, Mutations, SYT1-associated
related to Interactions · 3
SYT1 → S100A13, SNAP-25, STX1A
Band · 2
SYT1 → 10 D1|10 56.52 cM, 12q21.2
Chr. · 2
SYT1 → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
SYT1 → 108,846,843 bp, 79,452,008 bp
Aliases · 1
SYT1 → SYT1, P65, SVP65, SYT, synaptotagmin 1, BAGOS

Important terminology Word statistics

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Important terminology

bp human gene chr band chromosome 12 calcium location 10 protein mouse ion function omim search 452 008 end 79

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SYT1AliasesSYT1, P65, SVP65, SYT, synaptotagmin 1, BAGOS1.00infobox
SYT1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2K45, 2K4A, 2K8M, 2KI6, 2LHA, 2N1T, 2R83, 3F00, 3F01, 3F04, 3F05, 4ISQ, 4V111.00infobox
SYT1Band12q21.21.00infobox
SYT1Band10 D1|10 56.52 cM1.00infobox
SYT1Bgeemiddle temporal gyrus1.00infobox
SYT1BgeeBrodmann area 231.00infobox
SYT1Bgeeendothelial cell1.00infobox
SYT1Bgeelateral nuclear group of thalamus1.00infobox
SYT1Bgeeorbitofrontal cortex1.00infobox
SYT1Bgeefrontal pole1.00infobox
SYT1Bgeesuperior frontal gyrus1.00infobox
SYT1Bgeepons1.00infobox
SYT1BgeeBrodmann area 101.00infobox
SYT1Bgeecerebellar vermis1.00infobox
SYT1Bgeemedial dorsal nucleus1.00infobox
SYT1Bgeesubiculum1.00infobox
SYT1Bgeemedial geniculate nucleus1.00infobox
SYT1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
SYT1Bgeelateral geniculate nucleus1.00infobox
SYT1Bgeelateral septal nucleus1.00infobox
SYT1Bgeeprimary motor cortex1.00infobox
SYT1Bgeeprimary visual cortex1.00infobox
SYT1Bgeeneural layer of retina1.00infobox
SYT1BioGPSMore reference expression data1.00infobox
SYT1Chr.Chromosome 12 (human)1.00infobox
SYT1Chr.Chromosome 10 (mouse)1.00infobox
SYT1DatabasesNCBI: entry; OMA: entry1.00infobox
SYT1End79,452,008 bp1.00infobox
SYT1End108,846,843 bp1.00infobox
SYT1EnsemblENSG000000677151.00infobox

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