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Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene.
The analysis highlights Interactions, Function and Clinical Significance as prominent areas in the source structure around SYT1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around SYT1 shows recurring relationship patterns in the source. For example, SYT1 → 1-phosphatidylinositol binding, axon, brain development, calcium ion binding, calcium ion sensor activity, calcium ion-regulated exocytosis of neurotransmitter, calcium-dependent activation of synaptic vesicle fusion, calcium-dependent phospholipid binding, calcium-dependent protein binding, calcium-ion regulated exocytosis, calmodulin binding, cell differentiation, cell junction, cellular response to calcium ion, chemical synaptic transmission, chromaffin granule membrane, clathrin binding, clathrin-coated vesicle membrane, clathrin-sculpted acetylcholine transport vesicle membrane, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane Another extracted example is SYT1 → Brodmann area 10, Brodmann area 23, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, endothelial cell, frontal pole, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, neural layer of retina, orbitofrontal cortex, pons, primary motor cortex, primary visual cortex, subiculum, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp human gene chr band chromosome 12 calcium location 10 protein mouse ion function omim search 452 008 end 79
TTTA extracted 158 structured relationships around SYT1. Examples in this analysis include SYT1 → Aliases → SYT1, P65, SVP65, SYT, synaptotagmin 1, BAGOS and SYT1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2K45, 2K4A, 2K8M, 2KI6, 2LHA, 2N1T, 2R83, 3F00, 3F01, 3F04, 3F05, 4ISQ, 4V11. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SYT1 | Aliases | SYT1, P65, SVP65, SYT, synaptotagmin 1, BAGOS | 1.00 | infobox |
| SYT1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2K45, 2K4A, 2K8M, 2KI6, 2LHA, 2N1T, 2R83, 3F00, 3F01, 3F04, 3F05, 4ISQ, 4V11 | 1.00 | infobox |
| SYT1 | Band | 12q21.2 | 1.00 | infobox |
| SYT1 | Band | 10 D1|10 56.52 cM | 1.00 | infobox |
| SYT1 | Bgee | middle temporal gyrus | 1.00 | infobox |
| SYT1 | Bgee | Brodmann area 23 | 1.00 | infobox |
| SYT1 | Bgee | endothelial cell | 1.00 | infobox |
| SYT1 | Bgee | lateral nuclear group of thalamus | 1.00 | infobox |
| SYT1 | Bgee | orbitofrontal cortex | 1.00 | infobox |
| SYT1 | Bgee | frontal pole | 1.00 | infobox |
| SYT1 | Bgee | superior frontal gyrus | 1.00 | infobox |
| SYT1 | Bgee | pons | 1.00 | infobox |
| SYT1 | Bgee | Brodmann area 10 | 1.00 | infobox |
| SYT1 | Bgee | cerebellar vermis | 1.00 | infobox |
| SYT1 | Bgee | medial dorsal nucleus | 1.00 | infobox |
| SYT1 | Bgee | subiculum | 1.00 | infobox |
| SYT1 | Bgee | medial geniculate nucleus | 1.00 | infobox |
| SYT1 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| SYT1 | Bgee | lateral geniculate nucleus | 1.00 | infobox |
| SYT1 | Bgee | lateral septal nucleus | 1.00 | infobox |
| SYT1 | Bgee | primary motor cortex | 1.00 | infobox |
| SYT1 | Bgee | primary visual cortex | 1.00 | infobox |
| SYT1 | Bgee | neural layer of retina | 1.00 | infobox |
| SYT1 | BioGPS | More reference expression data | 1.00 | infobox |
| SYT1 | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| SYT1 | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| SYT1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SYT1 | End | 79,452,008 bp | 1.00 | infobox |
| SYT1 | End | 108,846,843 bp | 1.00 | infobox |
| SYT1 | Ensembl | ENSG00000067715 | 1.00 | infobox |
The concept neighborhoods around SYT1 bring nearby vocabulary together. In this analysis, examples include Gene, Calcium and Ion. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SYT1, one of the stronger structural bridges in this analysis connects SYT1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SYT1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Clinical Significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SYT1 · EN edition · Analysis: TopicsToTalkAbout