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SYNCRIP: Structure and function, Interactions & Overview

Synaptotagmin-binding, cytoplasmic RNA-interacting protein (SYNCRIP), also known as heterogeneous nuclear ribonucleoprotein (hnRNP) Q or NS1-associated protein-1 (NSAP-1), is a protein that in humans is encoded by the SYNCRIP gene. As the name implies, SYNCRIP is localized predominantly in the cytoplasm. It is evolutionarily conserved across eukaryotes…

Language: English [EN]
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SYNCRIP topic overview

The analysis highlights Structure and function, Interactions and Overview as prominent areas in the source structure around SYNCRIP.

Related topics
31
Source areas
3
Connected nodes
34
Extracted relationships
112
Concept neighborhoods
16
Bridge connections
34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure and function · 23 topics
Overview · 6 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, synaptotagmin binding cytoplasmic RNA interacting protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DGU, 2MXT, 2NBB
Band
6q14.3 · 9|9 E3.1
Bgee
ventricular zone · ganglionic eminence · amniotic fluid · skin of thigh · skin of hip
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 9 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure and function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SYNCRIP connects Entity context

The extracted context around SYNCRIP shows recurring relationship patterns in the source. For example, SYNCRIP → catalytic step 2 spliceosome, cellular response to interferon-gamma, CRD-mediated mRNA stability complex, CRD-mediated mRNA stabilization, cytoplasm, endoplasmic reticulum, GAIT complex, histone pre-mRNA 3'end processing complex, intracellular membrane-bounded organelle, membrane, mRNA 5'-UTR binding, mRNA binding, mRNA processing, mRNA splicing, via spliceosome, negative regulation of translation, nucleic acid binding, nucleoplasm, nucleus, osteoblast differentiation, poly(A) binding Another extracted example is SYNCRIP → AcD, Although, APOBEC-1, Arg-Gly-Gly, C-terminus, It, N-terminal, PPIs, RBPs, RGG, RNA, RNA-binding, RRM, RRM1, RRMs, The, The AcD, The RGG, The RRMs, There. Use these groups to spot repeated connection types before inspecting the individual relationships.

SYNCRIP

Top relations

Gene ontology · 28
SYNCRIP → catalytic step 2 spliceosome, cellular response to interferon-gamma, CRD-mediated mRNA stability complex, CRD-mediated mRNA stabilization, cytoplasm, endoplasmic reticulum, GAIT complex, histone pre-mRNA 3'end processing complex, intracellular membrane-bounded organelle, membrane, mRNA 5'-UTR binding, mRNA binding, mRNA processing, mRNA splicing, via spliceosome, negative regulation of translation, nucleic acid binding, nucleoplasm, nucleus, osteoblast differentiation, poly(A) binding
related to Structure and function · 21
SYNCRIP → AcD, Although, APOBEC-1, Arg-Gly-Gly, C-terminus, It, N-terminal, PPIs, RBPs, RGG, RNA, RNA-binding, RRM, RRM1, RRMs, The, The AcD, The RGG, The RRMs, There
Bgee · 18
SYNCRIP → abdominal wall, amniotic fluid, aortic valve, ascending aorta, epiblast, ganglionic eminence, hand, mandibular prominence, maxillary prominence, secondary oocyte, skin of hip, skin of thigh, sperm, stromal cell of endometrium, tail of embryo, tail of epididymis, tendon of biceps brachii, ventricular zone
RNA expression pattern · 18
SYNCRIP → abdominal wall, amniotic fluid, aortic valve, ascending aorta, epiblast, ganglionic eminence, hand, mandibular prominence, maxillary prominence, secondary oocyte, skin of hip, skin of thigh, sperm, stromal cell of endometrium, tail of embryo, tail of epididymis, tendon of biceps brachii, ventricular zone
related to Interactions · 4
SYNCRIP → ACF, APOBEC1, SYT7, SYT9
Band · 2
SYNCRIP → 6q14.3, 9|9 E3.1
Chr. · 2
SYNCRIP → Chromosome 6 (human), Chromosome 9 (mouse)
End · 2
SYNCRIP → 85,644,063 bp, 88,364,627 bp
Aliases · 1
SYNCRIP → SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, synaptotagmin binding cytoplasmic RNA interacting protein
Available structures · 1
SYNCRIP → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DGU, 2MXT, 2NBB

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

rna bp gene chr human band binding mrna chromosome complex cytoplasmic protein function domain isoform nuclear humans interactions location cytoplasm

SYNCRIP relationships Subject–Predicate–Object triples

TTTA extracted 112 structured relationships around SYNCRIP. Examples in this analysis include SYNCRIP → Aliases → SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, synaptotagmin binding cytoplasmic RNA interacting protein and SYNCRIP → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DGU, 2MXT, 2NBB. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SYNCRIPAliasesSYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, synaptotagmin binding cytoplasmic RNA interacting protein1.00infobox
SYNCRIPAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DGU, 2MXT, 2NBB1.00infobox
SYNCRIPBand6q14.31.00infobox
SYNCRIPBand9|9 E3.11.00infobox
SYNCRIPBgeeventricular zone1.00infobox
SYNCRIPBgeeganglionic eminence1.00infobox
SYNCRIPBgeeamniotic fluid1.00infobox
SYNCRIPBgeeskin of thigh1.00infobox
SYNCRIPBgeeskin of hip1.00infobox
SYNCRIPBgeetendon of biceps brachii1.00infobox
SYNCRIPBgeesperm1.00infobox
SYNCRIPBgeestromal cell of endometrium1.00infobox
SYNCRIPBgeesecondary oocyte1.00infobox
SYNCRIPBgeetail of epididymis1.00infobox
SYNCRIPBgeetail of embryo1.00infobox
SYNCRIPBgeeaortic valve1.00infobox
SYNCRIPBgeeascending aorta1.00infobox
SYNCRIPBgeemandibular prominence1.00infobox
SYNCRIPBgeehand1.00infobox
SYNCRIPBgeemaxillary prominence1.00infobox
SYNCRIPBgeeepiblast1.00infobox
SYNCRIPBgeeabdominal wall1.00infobox
SYNCRIPBioGPSMore reference expression data1.00infobox
SYNCRIPChr.Chromosome 6 (human)1.00infobox
SYNCRIPChr.Chromosome 9 (mouse)1.00infobox
SYNCRIPDatabasesNCBI: entry; OMA: entry1.00infobox
SYNCRIPEnd85,644,063 bp1.00infobox
SYNCRIPEnd88,364,627 bp1.00infobox
SYNCRIPEnsemblENSG000001353161.00infobox
SYNCRIPEntrez104921.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SYNCRIP bring nearby vocabulary together. In this analysis, examples include Translation, Acd and Three. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Gene
    • Ribonucleoprotein
    • Heterogeneous
    • Location
    • Chromosome
    • Function
    • Human
    • Nuclear
    • Bp
    • Chr
    • Syncrip
    • Binding
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Mouse
    • Ribonucleoprotein
    • Heterogeneous
    • Band
    • Function
    • Nuclear
  • heterogeneous nuclear ribonucleoproteins
    • Nuclear
    • Ribonucleoprotein
    • Hnrnp
    • Protein
    • Gene
    • Complex
    • Syncrip
    • Cellular
    • Cytoplasm
    • Mouse
    • Splicing
    • Rna
  • heterogeneous nuclear rna
    • Nuclear
    • Ribonucleoprotein
    • Hnrnp
    • Protein
    • Gene
    • Complex
    • Syncrip
    • Cellular
    • Cytoplasm
    • Mouse
    • Splicing
    • Box
  • gamma interferon (ifnγ)-activated inhibitor of translation
    • Gait
    • Complex
    • Component
    • Function
    • Cellular
    • Cytoplasm
    • Mouse
    • Ribonucleoprotein
    • Splicing
    • Also
    • Heterogeneous
    • Humans
  • structure and function
    • Gait
    • Location
    • Protein
    • Translation
    • Chromosome
    • Gene
    • Human
    • Syncrip
    • Bp
    • Chr
    • Complex
    • Binding
  • cytoplasm
    • Cellular
    • Mouse
    • Ribonucleoprotein
    • Splicing
    • Component
    • Gait
    • Heterogeneous
    • Location
    • Protein
    • Translation
    • Syncrip
    • Band
  • rna recognition motifs
    • Complex
    • Box
    • Component
    • Location
    • Proteins
    • Rgg
    • Syncrip
    • Acd
    • Domain
    • Cellular
    • Mouse
    • Splicing

Connections between topic areas Semantic bridges

For SYNCRIP, one of the stronger structural bridges in this analysis connects SYNCRIP with Structure and function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SYNCRIPStructure and function · splits 11 ⟂ 24
SYNCRIPOverview · splits 28 ⟂ 7
SYNCRIPInteractions · splits 32 ⟂ 3

Map overview Semantic statistics

SYNCRIP

Nodes35
Edges34
Triples112
Avg. degree1.94
Density0.057143
Components1

Source & methodology

TTTA analyzes the structure around SYNCRIP to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure and function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SYNCRIP · EN edition · Analysis: TopicsToTalkAbout

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