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Synaptophysin: Clinical significance, Tissue distribution & Structure

Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene.

Language: English [EN]
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Synaptophysin topic overview

The analysis highlights Clinical significance, Tissue distribution and Structure as prominent areas in the source structure around Synaptophysin.

Related topics
31
Source areas
7
Connected nodes
38
Extracted relationships
107
Concept neighborhoods
14
Bridge connections
38

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 15 topics
Tissue distribution · 4 topics
Function · 3 topics
Interactions · 3 topics
Structure · 3 topics
Overview · 2 topics
Gene · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SYP, MRX96, MRXsynaptophysin, XLID96
Band
Xp11.23 · X A1.1|X 3.44 cM
Bgee
right hemisphere of cerebellum · right frontal lobe · prefrontal cortex · Brodmann area 9 · anterior cingulate cortex
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene

Tissue distribution

Structure

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Synaptophysin connects Entity context

The extracted context around Synaptophysin shows recurring relationship patterns in the source. For example, Synaptophysin → cell junction, cellular response to organic substance, cholesterol binding, cytoplasmic vesicle, endocytosis, excitatory synapse, identical protein binding, integral component of membrane, integral component of synaptic vesicle membrane, membrane, neuromuscular junction, neuron projection, neuron projection terminus, perinuclear region of cytoplasm, presynaptic active zone, presynaptic membrane, protein self-association, regulation of long-term neuronal synaptic plasticity, regulation of neuronal synaptic plasticity, regulation of opioid receptor signaling pathway Another extracted example is Synaptophysin → amygdala, anterior cingulate cortex, anterior pituitary, Brodmann area 10, Brodmann area 9, C1 segment, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, habenula, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, neural layer of retina, nucleus accumbens, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, subiculum, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

Synaptophysin

Top relations

Gene ontology · 32
Synaptophysin → cell junction, cellular response to organic substance, cholesterol binding, cytoplasmic vesicle, endocytosis, excitatory synapse, identical protein binding, integral component of membrane, integral component of synaptic vesicle membrane, membrane, neuromuscular junction, neuron projection, neuron projection terminus, perinuclear region of cytoplasm, presynaptic active zone, presynaptic membrane, protein self-association, regulation of long-term neuronal synaptic plasticity, regulation of neuronal synaptic plasticity, regulation of opioid receptor signaling pathway
Bgee · 20
Synaptophysin → amygdala, anterior cingulate cortex, anterior pituitary, Brodmann area 10, Brodmann area 9, C1 segment, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, habenula, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, neural layer of retina, nucleus accumbens, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, subiculum, superior frontal gyrus
RNA expression pattern · 20
Synaptophysin → amygdala, anterior cingulate cortex, anterior pituitary, Brodmann area 10, Brodmann area 9, C1 segment, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, habenula, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, neural layer of retina, nucleus accumbens, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, subiculum, superior frontal gyrus
related to Biomarker · 4
Synaptophysin → As, Diagnostically, It, Using
related to External links · 3
Synaptophysin → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
Synaptophysin → X A1.1|X 3.44 cM, Xp11.23
Chr. · 2
Synaptophysin → X chromosome (human), X chromosome (mouse)
End · 2
Synaptophysin → 49,200,218 bp, 7,519,495 bp
related to Function · 2
Synaptophysin → Recent, The
related to Interactions · 2
Synaptophysin → AP1G1, SIAH2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp human chr band chromosome syp protein synaptic vesicle location function also mouse external neuroendocrine 200 218 end 49

Synaptophysin relationships Subject–Predicate–Object triples

TTTA extracted 107 structured relationships around Synaptophysin. Examples in this analysis include Synaptophysin → Aliases → SYP, MRX96, MRXsynaptophysin, XLID96 and Synaptophysin → Band → Xp11.23. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SynaptophysinAliasesSYP, MRX96, MRXsynaptophysin, XLID961.00infobox
SynaptophysinBandXp11.231.00infobox
SynaptophysinBandX A1.1|X 3.44 cM1.00infobox
SynaptophysinBgeeright hemisphere of cerebellum1.00infobox
SynaptophysinBgeeright frontal lobe1.00infobox
SynaptophysinBgeeprefrontal cortex1.00infobox
SynaptophysinBgeeBrodmann area 91.00infobox
SynaptophysinBgeeanterior cingulate cortex1.00infobox
SynaptophysinBgeeamygdala1.00infobox
SynaptophysinBgeeanterior pituitary1.00infobox
SynaptophysinBgeeBrodmann area 101.00infobox
SynaptophysinBgeenucleus accumbens1.00infobox
SynaptophysinBgeeC1 segment1.00infobox
SynaptophysinBgeeneural layer of retina1.00infobox
SynaptophysinBgeedentate gyrus of hippocampal formation granule cell1.00infobox
SynaptophysinBgeemedial dorsal nucleus1.00infobox
SynaptophysinBgeesuperior frontal gyrus1.00infobox
SynaptophysinBgeesubiculum1.00infobox
SynaptophysinBgeecerebellar cortex1.00infobox
SynaptophysinBgeemedial geniculate nucleus1.00infobox
SynaptophysinBgeedorsomedial hypothalamic nucleus1.00infobox
SynaptophysinBgeemedial vestibular nucleus1.00infobox
SynaptophysinBgeehabenula1.00infobox
SynaptophysinBioGPSMore reference expression data1.00infobox
SynaptophysinChr.X chromosome (human)1.00infobox
SynaptophysinChr.X chromosome (mouse)1.00infobox
SynaptophysinDatabasesNCBI: entry; OMA: entry1.00infobox
SynaptophysinEnd49,200,218 bp1.00infobox
SynaptophysinEnd7,519,495 bp1.00infobox
SynaptophysinEnsemblENSG000001020031.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Synaptophysin bring nearby vocabulary together. In this analysis, examples include Neuroendocrine, Cells and Shown. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Function
    • Location
    • Protein
    • Synaptic
    • Syp
    • Vesicle
    • Chromosome
    • Bp
    • Chr
    • Human
    • A1
    • Disability
  • function
    • Expressed
    • Gene
    • Location
    • Protein
    • Synaptic
    • Syp
    • Vesicle
    • Chromosome
    • Bp
    • Chr
    • External
    • Human
  • protein
    • Synaptic
    • Vesicle
    • Expressed
    • Function
    • Gene
    • Syp
    • A1
    • Cells
    • End
    • Mouse
    • Neural
    • Synapse
  • x chromosome
    • Bp
    • Human
    • Location
    • Band
    • A1
    • End
    • Mouse
    • Xp11
    • Gene
    • Function
    • Syp
    • External
  • synaptic transmission
    • Protein
    • Vesicle
    • Expressed
    • Function
    • Gene
    • Syp
    • A1
    • Cells
    • End
    • Mouse
    • Neural
    • Synapse
  • synaptic vesicle
    • Protein
    • Vesicle
    • Expressed
    • Function
    • Gene
    • Syp
    • A1
    • Cells
    • End
    • Mouse
    • Neural
    • Synapse
  • Synaptophysin
    • Neuroendocrine
    • Cells
    • Shown
    • Protein
    • Vesicle
    • Gene
    • Carcinoma
    • Expressed
    • Marker
    • Neural
    • Synapse
    • Tissues
  • synaptophysin
    • Neuroendocrine
    • Cells
    • Shown
    • Protein
    • Vesicle
    • Gene
    • Carcinoma
    • Expressed
    • Marker
    • Neural
    • Synapse
    • Tissues

Connections between topic areas Semantic bridges

For Synaptophysin, one of the stronger structural bridges in this analysis connects Synaptophysin with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SynaptophysinClinical significance · splits 23 ⟂ 16
SynaptophysinTissue distribution · splits 34 ⟂ 5
SynaptophysinStructure · splits 35 ⟂ 4
SynaptophysinFunction · splits 35 ⟂ 4
SynaptophysinInteractions · splits 35 ⟂ 4
SynaptophysinOverview · splits 36 ⟂ 3

Map overview Semantic statistics

Synaptophysin

Nodes39
Edges38
Triples107
Avg. degree1.95
Density0.051282
Components1

Source & methodology

TTTA analyzes the structure around Synaptophysin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Tissue distribution & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Synaptophysin · EN edition · Analysis: TopicsToTalkAbout

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