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Subtilase

Subtilases are a family of subtilisin-like serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like in the trypsin serine proteases. The structure of proteins in this family shows that they have an alpha/beta fold containing a 7-stranded parallel beta sheet.

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Human proteins containing this domain

FURINMBTPS1PCSK1PCSK2PCSK4
10 related topics

Overview

FamilySubtilisinSerine proteasesAspSer
18 related topics

Key facts & relationships

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AlphaFold
IPR000209 · PF00082
Available protein structures:
IPR000209 · PF00082
CDD
cd00306
InterPro
IPR000209
Membranome
546
MEROPS
S8

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Overview

Human proteins containing this domain

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Map overview Semantic statistics

Subtilase

Nodes31
Edges30
Triples13
Avg. degree1.94
Density0.064516
Components1

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Subtilase

Top relations

AlphaFold · 2
Subtilase → IPR000209, PF00082
Available protein structures: · 2
Subtilase → IPR000209, PF00082
CDD · 1
Subtilase → cd00306
InterPro · 1
Subtilase → IPR000209
Membranome · 1
Subtilase → 546
MEROPS · 1
Subtilase → S8
PDB · 1
Subtilase → IPR000209 PF00082 (ECOD; PDBsum)
Pfam · 1
Subtilase → PF00082
PROSITE · 1
Subtilase → PDOC00125
SCOP2 · 1
Subtilase → 1cse / SCOPe / SUPFAM

Important terminology Word statistics

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Important terminology

family subtilisin catalytic known proteins asp ser endopeptidases serine triad amino sequence members enzymes containing peptidase structures kexin subtilases proteases

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SubtilaseAlphaFoldIPR0002091.00infobox
SubtilaseAlphaFoldPF000821.00infobox
SubtilaseAvailable protein structures:IPR0002091.00infobox
SubtilaseAvailable protein structures:PF000821.00infobox
SubtilaseCDDcd003061.00infobox
SubtilaseInterProIPR0002091.00infobox
SubtilaseMembranome5461.00infobox
SubtilaseMEROPSS81.00infobox
SubtilasePDBIPR000209 PF00082 (ECOD; PDBsum)1.00infobox
SubtilasePfamPF000821.00infobox
SubtilasePROSITEPDOC001251.00infobox
SubtilaseSCOP21cse / SCOPe / SUPFAM1.00infobox
SubtilaseSymbolPeptidase_S81.00infobox

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