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Subtilase: Human proteins containing this domain & Overview

Subtilases are a family of subtilisin-like serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like in the trypsin serine proteases. The structure of proteins in this family shows that they have an alpha/beta fold containing a 7-stranded parallel beta sheet.

Language: English [EN]
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Subtilase topic overview

The analysis highlights Human proteins containing this domain and Overview as prominent areas in the source structure around Subtilase. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
27
Source areas
2
Connected nodes
30
Extracted relationships
13
Related term clusters
16
Bridge connections
30

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 18 topics
Human proteins containing this domain · 10 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR000209 · PF00082
Available protein structures:
IPR000209 · PF00082
CDD
cd00306
InterPro
IPR000209
Membranome
546
MEROPS
S8

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Human proteins containing this domain

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Subtilase connects Entity context

The extracted context around Subtilase shows recurring relationship patterns in the source. For example, Subtilase → IPR000209, PF00082 Another extracted example is Subtilase → cd00306. Use these groups to spot repeated connection types before inspecting the individual relationships.

Subtilase

Top relations

AlphaFold · 2
Subtilase → IPR000209, PF00082
Available protein structures: · 2
Subtilase → IPR000209, PF00082
CDD · 1
Subtilase → cd00306
InterPro · 1
Subtilase → IPR000209
Membranome · 1
Subtilase → 546
MEROPS · 1
Subtilase → S8
PDB · 1
Subtilase → IPR000209 PF00082 (ECOD; PDBsum)
Pfam · 1
Subtilase → PF00082
PROSITE · 1
Subtilase → PDOC00125
SCOP2 · 1
Subtilase → 1cse / SCOPe / SUPFAM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

family subtilisin catalytic known proteins asp ser endopeptidases serine triad amino sequence members enzymes containing peptidase structures kexin subtilases proteases

Subtilase relationships Subject–Predicate–Object triples

TTTA extracted 13 structured relationships around Subtilase. Examples in this analysis include Subtilase → AlphaFold → IPR000209 and Subtilase → AlphaFold → PF00082. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SubtilaseAlphaFoldIPR0002091.00infobox
SubtilaseAlphaFoldPF000821.00infobox
SubtilaseAvailable protein structures:IPR0002091.00infobox
SubtilaseAvailable protein structures:PF000821.00infobox
SubtilaseCDDcd003061.00infobox
SubtilaseInterProIPR0002091.00infobox
SubtilaseMembranome5461.00infobox
SubtilaseMEROPSS81.00infobox
SubtilasePDBIPR000209 PF00082 (ECOD; PDBsum)1.00infobox
SubtilasePfamPF000821.00infobox
SubtilasePROSITEPDOC001251.00infobox
SubtilaseSCOP21cse / SCOPe / SUPFAM1.00infobox
SubtilaseSymbolPeptidase_S81.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Subtilase bring nearby vocabulary together. In this analysis, examples include Subtilisin, Although and Protease. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • family
    • Subtilisin
    • Although
    • Protease
    • Endopeptidases
    • Members
    • Peptidase
    • Serine
    • Proteins
    • Chymotrypsins
    • Exopeptidase
    • Different
    • Fold
  • catalytic triad
    • Ser
    • Triad
    • Enzymes
    • Subtilisin
    • Chymotrypsins
    • Presence
    • Well
    • Acid
    • Acids
    • Although
    • Different
    • Fold
  • human proteins containing this domain
    • Fold
    • Structure
    • Show
    • Similarity
    • Subtilisins
    • Containing
    • Proteins
    • Subtilisin
    • Acids
    • Chymotrypsins
    • Human
    • Although
  • asp
    • Ser
    • Triad
    • Catalytic
    • Chymotrypsins
    • Acid
    • Although
    • Different
    • Presence
    • Proteases
    • Show
    • Similarity
    • Subtilisins
  • mosaic proteins
    • Show
    • Similarity
    • Structure
    • Subtilisins
    • Containing
    • Subtilisin
    • Chymotrypsins
    • Although
    • Different
    • Fold
    • Human
    • Protein
  • ser
    • Triad
    • Chymotrypsins
    • Acid
    • Although
    • Different
    • Presence
    • Show
    • Similarity
    • Subtilisins
    • Well
    • Enzymes
    • Members
  • chymotrypsins
    • Different
    • Show
    • Similarity
    • Subtilisins
    • Members
    • Ser
    • Structures
    • Triad
    • Proteins
    • Subtilisin
    • Family
  • endopeptidases
    • Kexin
    • Peptidase
    • Exopeptidase
    • Although
    • Family
    • Furin
    • Subfamily
    • Enzymes
    • Members
    • Known

Connections between topic areas Semantic bridges

For Subtilase, one of the stronger structural bridges in this analysis connects Subtilase with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Subtilase — Overview · splits 12 ⟂ 19
Subtilase — Human proteins containing this domain · splits 20 ⟂ 11

Map overview Semantic statistics

Subtilase

Nodes31
Edges30
Triples13
Avg. degree1.94
Density0.064516
Components1

Source & methodology

TTTA analyzes the structure around Subtilase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Human proteins containing this domain & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Subtilase · EN edition · Analysis: TopicsToTalkAbout

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