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STARR-seq

STARR-seq (short for self-transcribing active regulatory region sequencing) is a method to assay enhancer activity for millions of candidates from arbitrary sources of DNA. It is used to identify the sequences that act as transcriptional enhancers in a direct, quantitative, and genome-wide manner.

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Overview

Enhancer detection

Application

Future directions

Advanced semantic analysis

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Map overview Semantic statistics

STARR-seq

Nodes38
Edges37
Triples19
Avg. degree1.95
Density0.052632
Components1

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STARR-seq

Top relations

related to Application · 10
STARR-seq → DNA, DNase-seq, FAIRE-seq, High, However, RNAs, Such, Taking, The, Yet
related to Future directions · 4
STARR-seq → By, Recently, The, Therefore
related to Quantifying enhancer activity · 3
STARR-seq → Cloning ChIP DNA, DNA, This

Important terminology Word statistics

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Important terminology

enhancers transcription enhancer regulatory activity sequences promoter dna genes cell factors genome-wide approach fragments sites gene manner candidate active sequencing

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
deep sequencing of DNase I hypersensitive sitesinstance ofDevelopment of new methods0.80text
the transcription factorsinstance ofThe strongest enhancers were near housekeeping genes such as enzymes or component of the cytoskeleton and developmental regulators0.80text
STARR-seqrelated to ApplicationHowever0.60section
STARR-seqrelated to ApplicationDNase-seq0.60section
STARR-seqrelated to ApplicationFAIRE-seq0.60section
STARR-seqrelated to ApplicationYet0.60section
STARR-seqrelated to ApplicationHigh0.60section
STARR-seqrelated to ApplicationThe0.60section
STARR-seqrelated to ApplicationTaking0.60section
STARR-seqrelated to ApplicationRNAs0.60section
STARR-seqrelated to ApplicationSuch0.60section
STARR-seqrelated to ApplicationDNA0.60section

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