SMURF2

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Interactions

Interact Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7

9 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

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2.3.2.26: ↗
Aliases: SMURF2, SMAD specific E3 ubiquitin protein ligase 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZVD, 2DJY, 2JQZ, 2KXQ, 2LTZ
Band: 17q23.3-q24.1 · 11|11 E1
Bgee: buccal mucosa cell · secondary oocyte · amniotic fluid · pylorus · saphenous vein
BioGPS: More reference expression data

Topics to explore

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Overview

Interactions

Interact Protein-protein interaction
Mothers against decapentaplegic homolog 1
Mothers against decapentaplegic homolog 2
Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 7
SCYE1
SMURF1
Ubiquitin C
TOP2A

Advanced semantic analysis

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Map overview Semantic statistics

Nodes14

Edges13

Triples99

Avg. degree1.86

Density0.142857

Components1

How this topic connects Entity context

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SMURF2

Top relations

Gene ontology · 32

SMURF2 → BMP signaling pathway, cytoplasm, cytosol, identical protein binding, membrane, membrane raft, negative regulation of BMP signaling pathway, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, negative regulation of transforming growth factor beta receptor signaling pathway, nuclear speck, nucleoplasm, nucleus, plasma membrane, positive regulation of canonical Wnt signaling pathway, positive regulation of protein catabolic process, positive regulation of trophoblast cell migration, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding, protein deubiquitination

Bgee · 19

SMURF2 → Achilles tendon, amniotic fluid, buccal mucosa cell, caput epididymis, endothelial cell of lymphatic vessel, genital tubercle, hand, lactiferous duct, left lung lobe, otolith organ, pericardium, pylorus, right lung lobe, saphenous vein, secondary oocyte, superior cervical ganglion, utricle, visceral pleura, zygote

RNA expression pattern · 19

related to Interactions · 3

SMURF2 → Mothers, SCYE1, SMURF1

Band · 2

SMURF2 → 11|11 E1, 17q23.3-q24.1

Chr. · 2

SMURF2 → Chromosome 11 (mouse), Chromosome 17 (human)

End · 2

SMURF2 → 106,811,541 bp, 64,662,307 bp

2.3.2.26 · 1

SMURF2 → ↗

Aliases · 1

SMURF2 → SMURF2, SMAD specific E3 ubiquitin protein ligase 2

Available structures · 1

SMURF2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZVD, 2DJY, 2JQZ, 2KXQ, 2LTZ

Important terminology Word statistics

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Important terminology

bp chromosome chr human band gene 17 ligase 3-q24 location ubiquitin enzyme mouse e3 ubiquitin-protein 17q23 smad protein search activity

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
SMURF2	2.3.2.26	↗	1.00	infobox
SMURF2	Aliases	SMURF2, SMAD specific E3 ubiquitin protein ligase 2	1.00	infobox
SMURF2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZVD, 2DJY, 2JQZ, 2KXQ, 2LTZ	1.00	infobox
SMURF2	Band	17q23.3-q24.1	1.00	infobox
SMURF2	Band	11\|11 E1	1.00	infobox
SMURF2	Bgee	buccal mucosa cell	1.00	infobox
SMURF2	Bgee	secondary oocyte	1.00	infobox
SMURF2	Bgee	amniotic fluid	1.00	infobox
SMURF2	Bgee	pylorus	1.00	infobox
SMURF2	Bgee	saphenous vein	1.00	infobox
SMURF2	Bgee	lactiferous duct	1.00	infobox
SMURF2	Bgee	visceral pleura	1.00	infobox
SMURF2	Bgee	pericardium	1.00	infobox
SMURF2	Bgee	caput epididymis	1.00	infobox
SMURF2	Bgee	Achilles tendon	1.00	infobox
SMURF2	Bgee	hand	1.00	infobox
SMURF2	Bgee	otolith organ	1.00	infobox
SMURF2	Bgee	utricle	1.00	infobox
SMURF2	Bgee	zygote	1.00	infobox
SMURF2	Bgee	left lung lobe	1.00	infobox
SMURF2	Bgee	right lung lobe	1.00	infobox
SMURF2	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
SMURF2	Bgee	genital tubercle	1.00	infobox
SMURF2	Bgee	superior cervical ganglion	1.00	infobox
SMURF2	BioGPS	More reference expression data	1.00	infobox
SMURF2	Chr.	Chromosome 17 (human)	1.00	infobox
SMURF2	Chr.	Chromosome 11 (mouse)	1.00	infobox
SMURF2	Databases	NCBI: entry; OMA: entry	1.00	infobox
SMURF2	End	64,662,307 bp	1.00	infobox
SMURF2	End	106,811,541 bp	1.00	infobox

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