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SGK3: Function, Interactions & Overview

Serine/threonine-protein kinase Sgk3 is an enzyme that in humans is encoded by the SGK3 gene.

Language: English [EN]
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SGK3 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around SGK3.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
97
Concept neighborhoods
9
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 9 topics
Interactions · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
Aliases
SGK3, CISK, SGK2, SGKL, serum/glucocorticoid regulated kinase family member 3
Band
8q13.1 · 1 A2|1 2.08 cM
Bgee
retinal pigment epithelium · corpus callosum · inferior ganglion of vagus nerve · mucosa of ileum · subthalamic nucleus
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SGK3 connects Entity context

The extracted context around SGK3 shows recurring relationship patterns in the source. For example, SGK3 → ATP binding, calcium channel regulator activity, chloride channel regulator activity, cytoplasmic vesicle, cytosol, early endosome, endosome, intracellular signal transduction, ion transmembrane transport, kinase activity, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, nucleotide binding, peptidyl-serine phosphorylation, phosphatidylinositol binding, phosphorylation, positive regulation of transporter activity, potassium channel regulator activity, protein binding, protein kinase activity, protein phosphorylation Another extracted example is SGK3 → cornea, corpus callosum, endothelial cell of lymphatic vessel, Epithelium of choroid plexus, gastrula, granulocyte, hair follicle, inferior ganglion of vagus nerve, jejunal mucosa, medulla oblongata, molar, mucosa of ileum, pars reticulata, retinal pigment epithelium, skin of arm, skin of hip, stria vascularis, subthalamic nucleus, vestibular membrane of cochlear duct. Use these groups to spot repeated connection types before inspecting the individual relationships.

SGK3

Top relations

Gene ontology · 29
SGK3 → ATP binding, calcium channel regulator activity, chloride channel regulator activity, cytoplasmic vesicle, cytosol, early endosome, endosome, intracellular signal transduction, ion transmembrane transport, kinase activity, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, nucleotide binding, peptidyl-serine phosphorylation, phosphatidylinositol binding, phosphorylation, positive regulation of transporter activity, potassium channel regulator activity, protein binding, protein kinase activity, protein phosphorylation
Bgee · 19
SGK3 → cornea, corpus callosum, endothelial cell of lymphatic vessel, Epithelium of choroid plexus, gastrula, granulocyte, hair follicle, inferior ganglion of vagus nerve, jejunal mucosa, medulla oblongata, molar, mucosa of ileum, pars reticulata, retinal pigment epithelium, skin of arm, skin of hip, stria vascularis, subthalamic nucleus, vestibular membrane of cochlear duct
RNA expression pattern · 19
SGK3 → cornea, corpus callosum, endothelial cell of lymphatic vessel, Epithelium of choroid plexus, gastrula, granulocyte, hair follicle, inferior ganglion of vagus nerve, jejunal mucosa, medulla oblongata, molar, mucosa of ileum, pars reticulata, retinal pigment epithelium, skin of arm, skin of hip, stria vascularis, subthalamic nucleus, vestibular membrane of cochlear duct
related to Function · 6
SGK3 → Alternate, In, MITF, PX, The, This
Band · 2
SGK3 → 1 A2|1 2.08 cM, 8q13.1
Chr. · 2
SGK3 → Chromosome 1 (mouse), Chromosome 8 (human)
End · 2
SGK3 → 66,862,022 bp, 9,971,070 bp
2.7.11.1 · 1
SGK3 → ↗
Aliases · 1
SGK3 → SGK3, CISK, SGK2, SGKL, serum/glucocorticoid regulated kinase family member 3
BioGPS · 1
SGK3 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band kinase chromosome serine location enzyme mouse protein function activity 862 022 end 66 a2 08

SGK3 relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around SGK3. Examples in this analysis include SGK3 → 2.7.11.1 → ↗ and SGK3 → Aliases → SGK3, CISK, SGK2, SGKL, serum/glucocorticoid regulated kinase family member 3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SGK32.7.11.11.00infobox
SGK3AliasesSGK3, CISK, SGK2, SGKL, serum/glucocorticoid regulated kinase family member 31.00infobox
SGK3Band8q13.11.00infobox
SGK3Band1 A2|1 2.08 cM1.00infobox
SGK3Bgeeretinal pigment epithelium1.00infobox
SGK3Bgeecorpus callosum1.00infobox
SGK3Bgeeinferior ganglion of vagus nerve1.00infobox
SGK3Bgeemucosa of ileum1.00infobox
SGK3Bgeesubthalamic nucleus1.00infobox
SGK3Bgeeskin of arm1.00infobox
SGK3Bgeepars reticulata1.00infobox
SGK3Bgeejejunal mucosa1.00infobox
SGK3Bgeemedulla oblongata1.00infobox
SGK3Bgeeskin of hip1.00infobox
SGK3Bgeevestibular membrane of cochlear duct1.00infobox
SGK3BgeeEpithelium of choroid plexus1.00infobox
SGK3Bgeemolar1.00infobox
SGK3Bgeegastrula1.00infobox
SGK3Bgeegranulocyte1.00infobox
SGK3Bgeehair follicle1.00infobox
SGK3Bgeeendothelial cell of lymphatic vessel1.00infobox
SGK3Bgeecornea1.00infobox
SGK3Bgeestria vascularis1.00infobox
SGK3BioGPSMore reference expression data1.00infobox
SGK3Chr.Chromosome 8 (human)1.00infobox
SGK3Chr.Chromosome 1 (mouse)1.00infobox
SGK3DatabasesNCBI: entry; OMA: entry1.00infobox
SGK3End66,862,022 bp1.00infobox
SGK3End9,971,070 bp1.00infobox
SGK3EnsemblENSG000001042051.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SGK3 bring nearby vocabulary together. In this analysis, examples include Activity, Expression and Family. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SGK3
    • Activity
    • Expression
    • Family
    • Function
    • Member
    • Regulated
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
  • sgk3
    • Activity
    • Expression
    • Family
    • Function
    • Member
    • Regulated
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
  • gene
    • Sgk3
    • Kinase
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • A2
    • Activity
    • End
    • Expression
    • Family
  • serine/threonine protein kinase
    • Transport
    • Activity
    • Enzyme
    • Family
    • Function
    • Kinase
    • Member
    • Serine
    • Gene
    • Sgk3
    • Encoded
    • Humans
  • function
    • Activity
    • Family
    • Member
    • Kinase
    • Location
    • Chromosome
    • Human
    • Interactions
    • Reading
    • References
    • Threonine
    • Bp
  • enzyme
    • Kinase
    • Encoded
    • Humans
    • Interactions
    • Reading
    • References
    • Threonine-protein
    • Gene
    • Sgk3
    • Activity
    • Family
    • Function
  • chloride channels
    • Potassium
    • Protein
    • Transport
    • Threonine
    • End
    • Expression
    • Family
    • Function
    • Member
    • Mouse
    • Serine
    • Kinase
  • interactions
    • Reading
    • References
    • Member
    • Regulated
    • Kinase
    • Location
    • Human
    • Sgk3

Connections between topic areas Semantic bridges

For SGK3, one of the stronger structural bridges in this analysis connects SGK3 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SGK3Function · splits 7 ⟂ 10
SGK3Overview · splits 14 ⟂ 3
SGK3Interactions · splits 14 ⟂ 3

Map overview Semantic statistics

SGK3

Nodes17
Edges16
Triples97
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around SGK3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SGK3 · EN edition · Analysis: TopicsToTalkAbout

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