SDHD

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Structure

Chromosome 11 Locus Base pairs Pseudogenes Chromosomes 1

16 related topics

Clinical significance

Paraganglioma Germline mutations Pheochromocytoma Hypoxic SDHAF2

14 related topics

Function

Complex II Ubiquinone Succinate Deprotonation FAD

11 related topics

Overview

Protein Gene Enzyme Citric acid cycle Electron transport chain

5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: SDHD, CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS, succinate dehydrogenase complex subunit D, MC2DN3
Band: 11q23.1 · 9|9 A5.3
Bgee: jejunal mucosa · rectum · kidney tubule · biceps brachii · mucosa of colon
BioGPS: n/a
Chr.: Chromosome 11 (human) · Chromosome 9 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Structure

Chromosome 11
Locus Locus (genetics)
Base pairs
Pseudogenes
Chromosomes 1 Chromosome 1
18 Chromosome 18
Amino acids
Succinate dehydrogenase
Protein complex
Mitochondrial inner membrane
Transmembrane
SDHC Succinate dehydrogenase complex subunit C
SDHC SDHC (gene)
Dimer Protein dimer
SDHB
SDHA

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes51

Edges50

Triples117

Avg. degree1.96

Density0.039216

Components1

How this topic connects Entity context

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SDHD

Top relations

Bgee · 20

SDHD → biceps brachii, cardiac muscle tissue of left ventricle, cardiac muscles, digastric muscle, extraocular muscle, intercostal muscle, interventricular septum, jejunal mucosa, kidney tubule, mucosa of colon, mucosa of sigmoid colon, mucosa of transverse colon, myocardium of ventricle, rectum, right kidney, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, thoracic diaphragm

RNA expression pattern · 20

related to Function · 16

SDHD → Complex II, FAD, Fe-S, Following, Initially, O4, SDHA, SDHB, SDHC, SDHC/SDHD, Ser27, The, The O1, The SDHC/SDHD, This, Tyr83

Gene ontology · 14

SDHD → electron transfer activity, heme binding, integral component of membrane, membrane, metal ion binding, mitochondrial electron transport, succinate to ubiquinone, mitochondrial envelope, mitochondrial inner membrane, mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), mitochondrion, succinate dehydrogenase (ubiquinone) activity, succinate dehydrogenase activity, tricarboxylic acid cycle, ubiquinone binding

related to Clinical significance · 13

SDHD → Andes, As, Because, Germline, Mutations, Notably, People, SDH, SDHAF2, SDHB, SDHC, Since, The

related to Structure · 8

SDHD → Complex II, SDHA, SDHB, SDHC, The, The SDHC/SDHD, The SDHD, There

related to External links · 6

SDHD → Archived, GeneReviews/NCBI/NIH/UW, Hereditary Paraganglioma-Pheochromocytoma SyndromesSDHD, HUGO Gene Nomenclature Committee, March, Wayback Machine

Band · 2

SDHD → 11q23.1, 9|9 A5.3

Chr. · 2

SDHD → Chromosome 11 (human), Chromosome 9 (mouse)

End · 2

SDHD → 112,120,016 bp, 50,515,112 bp

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene succinate ubiquinone syndrome complex sdhc mutations bp protein dehydrogenase subunit electron chr human band chromosome 11 mitochondrial sdhb enzyme

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
SDHD	Aliases	SDHD, CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS, succinate dehydrogenase complex subunit D, MC2DN3	1.00	infobox
SDHD	Band	11q23.1	1.00	infobox
SDHD	Band	9\|9 A5.3	1.00	infobox
SDHD	Bgee	jejunal mucosa	1.00	infobox
SDHD	Bgee	rectum	1.00	infobox
SDHD	Bgee	kidney tubule	1.00	infobox
SDHD	Bgee	biceps brachii	1.00	infobox
SDHD	Bgee	mucosa of colon	1.00	infobox
SDHD	Bgee	right ventricle	1.00	infobox
SDHD	Bgee	mucosa of sigmoid colon	1.00	infobox
SDHD	Bgee	mucosa of transverse colon	1.00	infobox
SDHD	Bgee	Skeletal muscle tissue of biceps brachii	1.00	infobox
SDHD	Bgee	Skeletal muscle tissue of rectus abdominis	1.00	infobox
SDHD	Bgee	right kidney	1.00	infobox
SDHD	Bgee	interventricular septum	1.00	infobox
SDHD	Bgee	extraocular muscle	1.00	infobox
SDHD	Bgee	myocardium of ventricle	1.00	infobox
SDHD	Bgee	intercostal muscle	1.00	infobox
SDHD	Bgee	cardiac muscles	1.00	infobox
SDHD	Bgee	digastric muscle	1.00	infobox
SDHD	Bgee	cardiac muscle tissue of left ventricle	1.00	infobox
SDHD	Bgee	thoracic diaphragm	1.00	infobox
SDHD	Bgee	sternocleidomastoid muscle	1.00	infobox
SDHD	BioGPS	n/a	1.00	infobox
SDHD	Chr.	Chromosome 11 (human)	1.00	infobox
SDHD	Chr.	Chromosome 9 (mouse)	1.00	infobox
SDHD	Databases	NCBI: entry; OMA: entry	1.00	infobox
SDHD	End	112,120,016 bp	1.00	infobox
SDHD	End	50,515,112 bp	1.00	infobox
SDHD	Ensembl	ENSG00000204370	1.00	infobox

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