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SDHB

Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) also known as iron-sulfur subunit of complex II (Ip) is a protein that in humans is encoded by the SDHB gene.

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1.3.5.1
↗
Aliases
SDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP, succinate dehydrogenase complex iron sulfur subunit B, MC2DN4
Band
1p36.13 · 4|4 D3
Bgee
left ventricle · apex of heart · gastrocnemius muscle · muscle of thigh · mucosa of transverse colon
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

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SDHB

Nodes60
Edges59
Triples127
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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SDHB

Top relations

Gene ontology · 23
SDHB → 2 iron, 2 sulfur cluster binding, 3 iron, 4 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, aerobic dissimilation, electron transfer activity, electron transport chain, iron-sulfur cluster binding, membrane, metal ion binding, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), mitochondrion, nucleoplasm, oxidoreductase activity, plasma membrane, protein binding, respiratory chain complex II, respiratory electron transport chain, succinate dehydrogenase (ubiquinone) activity
Bgee · 19
SDHB → apex of heart, biceps brachii, cardiac muscle tissue of left ventricle, cardiac muscles, digastric muscle, gastrocnemius muscle, interventricular septum, left ventricle, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, plantaris muscle, right auricle of heart, right lobe of liver, right ventricle, soleus muscle, sternocleidomastoid muscle, thoracic diaphragm, vastus lateralis muscle
RNA expression pattern · 19
SDHB → apex of heart, biceps brachii, cardiac muscle tissue of left ventricle, cardiac muscles, digastric muscle, gastrocnemius muscle, interventricular septum, left ventricle, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, plantaris muscle, right auricle of heart, right lobe of liver, right ventricle, soleus muscle, sternocleidomastoid muscle, thoracic diaphragm, vastus lateralis muscle
related to Function · 13
SDHB → Citric Acid Cycle, Electrons, FAD, FADH2, Figure, Finally, Respiratory, SDH, SDHA, SDHC/SDHD, The SDH, This, Ubiquinone
related to Cancer · 9
SDHB → Currently, In, Malignancy, Malignant, Paragangliomas, SDHD, Sporadic, The, This
related to Structure · 7
SDHB → DNA, However, It, SDHA, SDHC, SDHD, The
related to Clinical significance · 6
SDHB → Germline, Less, Paraganglioma Type PGL4, Paragangliomas, The, When
related to RNA editing · 4
SDHB → ORF, R46X, The, This
related to External links · 3
SDHB → Archived, Database, Wayback Machine
Band · 2
SDHB → 1p36.13, 4|4 D3

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Important terminology

succinate protein gene ubiquinone complex sdhd sdh sdhc subunit human cell dehydrogenase bp sdha mitochondrial chr band electrons mutations iron

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SDHB1.3.5.1↗1.00infobox
SDHBAliasesSDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP, succinate dehydrogenase complex iron sulfur subunit B, MC2DN41.00infobox
SDHBBand1p36.131.00infobox
SDHBBand4|4 D31.00infobox
SDHBBgeeleft ventricle1.00infobox
SDHBBgeeapex of heart1.00infobox
SDHBBgeegastrocnemius muscle1.00infobox
SDHBBgeemuscle of thigh1.00infobox
SDHBBgeemucosa of transverse colon1.00infobox
SDHBBgeeright ventricle1.00infobox
SDHBBgeeright auricle of heart1.00infobox
SDHBBgeeright lobe of liver1.00infobox
SDHBBgeevastus lateralis muscle1.00infobox
SDHBBgeebiceps brachii1.00infobox
SDHBBgeemyocardium of ventricle1.00infobox
SDHBBgeedigastric muscle1.00infobox
SDHBBgeeinterventricular septum1.00infobox
SDHBBgeeplantaris muscle1.00infobox
SDHBBgeesternocleidomastoid muscle1.00infobox
SDHBBgeecardiac muscles1.00infobox
SDHBBgeesoleus muscle1.00infobox
SDHBBgeethoracic diaphragm1.00infobox
SDHBBgeecardiac muscle tissue of left ventricle1.00infobox
SDHBBioGPSn/a1.00infobox
SDHBChr.Chromosome 1 (human)1.00infobox
SDHBChr.Chromosome 4 (mouse)1.00infobox
SDHBDatabasesNCBI: entry; OMA: entry1.00infobox
SDHBEnd17,054,032 bp1.00infobox
SDHBEnd140,706,504 bp1.00infobox
SDHBEnsemblENSG000001171181.00infobox

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