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SCP2: Function, Interactions & Clinical significance

Non-specific lipid-transfer protein also known as sterol carrier protein 2 (SCP-2) or propanoyl-CoA C-acyltransferase is a protein that in humans is encoded by the SCP2 gene.

Language: English [EN]
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SCP2 topic overview

The analysis highlights Function, Interactions and Clinical significance as prominent areas in the source structure around SCP2.

Related topics
11
Source areas
4
Connected nodes
15
Extracted relationships
113
Related term clusters
7
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 4 topics
Interactions · 3 topics
Clinical significance · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.1.155
↗
2.3.1.16
↗
2.3.1.176
↗
Aliases
SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX, sterol carrier protein 2, SCOX
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QND, 2C0L
Band
1p32.3 · 4 C7|4 50.2 cM

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How SCP2 connects Entity context

The extracted context around SCP2 shows recurring relationship patterns in the source. For example, SCP2 → acyltransferase activity, acyltransferase activity, transferring groups other than amino-acyl groups, alpha-linolenic acid metabolic process, bile acid biosynthetic process, catalytic activity, cholesterol binding, cytoplasm, cytosol, extracellular exosome, fatty acid beta-oxidation using acyl-CoA oxidase, fatty-acyl-CoA binding, inositol trisphosphate biosynthetic process, intracellular membrane-bounded organelle, lipid binding, lipid hydroperoxide transport, lipid transport, long-chain fatty acyl-CoA binding, membrane, metabolism, mitochondrion Another extracted example is SCP2 → colon, duodenum, epithelium of nasopharynx, gallbladder, germinal epithelium, granulocyte, hepatobiliary system, human kidney, jejunal mucosa, jejunum, liver, mucosa of sigmoid colon, palpebral conjunctiva, proximal tubule, pylorus, rectum, right kidney, right lobe of liver, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.

SCP2

Top relations

Gene ontology · 42
SCP2 → acyltransferase activity, acyltransferase activity, transferring groups other than amino-acyl groups, alpha-linolenic acid metabolic process, bile acid biosynthetic process, catalytic activity, cholesterol binding, cytoplasm, cytosol, extracellular exosome, fatty acid beta-oxidation using acyl-CoA oxidase, fatty-acyl-CoA binding, inositol trisphosphate biosynthetic process, intracellular membrane-bounded organelle, lipid binding, lipid hydroperoxide transport, lipid transport, long-chain fatty acyl-CoA binding, membrane, metabolism, mitochondrion
Bgee · 19
SCP2 → colon, duodenum, epithelium of nasopharynx, gallbladder, germinal epithelium, granulocyte, hepatobiliary system, human kidney, jejunal mucosa, jejunum, liver, mucosa of sigmoid colon, palpebral conjunctiva, proximal tubule, pylorus, rectum, right kidney, right lobe of liver, white adipose tissue
RNA expression pattern · 19
SCP2 → colon, duodenum, epithelium of nasopharynx, gallbladder, germinal epithelium, granulocyte, hepatobiliary system, human kidney, jejunal mucosa, jejunum, liver, mucosa of sigmoid colon, palpebral conjunctiva, proximal tubule, pylorus, rectum, right kidney, right lobe of liver, white adipose tissue
related to Function · 4
SCP2 → Alternative, C-terminus, Evidence, SCPx
Band · 2
SCP2 → 1p32.3, 4 C7|4 50.2 cM
Chr. · 2
SCP2 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
SCP2 → 108,002,195 bp, 53,051,698 bp
related to Interactions · 2
SCP2 → Caveolin, PEX5
2.3.1.155 · 1
SCP2 → ↗
2.3.1.16 · 1
SCP2 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp protein chr human band sterol chromosome scpx carrier location mouse lipid scp-2 propanoyl-coa c-acyltransferase function transcript search activity

SCP2 relationships Subject–Predicate–Object triples

TTTA extracted 113 structured relationships around SCP2. Examples in this analysis include SCP2 → 2.3.1.155 → ↗ and SCP2 → Aliases → SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX, sterol carrier protein 2, SCOX. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SCP22.3.1.155↗1.00infobox
SCP22.3.1.16↗1.00infobox
SCP22.3.1.176↗1.00infobox
SCP2AliasesSCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX, sterol carrier protein 2, SCOX1.00infobox
SCP2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QND, 2C0L1.00infobox
SCP2Band1p32.31.00infobox
SCP2Band4 C7|4 50.2 cM1.00infobox
SCP2Bgeejejunal mucosa1.00infobox
SCP2Bgeeright lobe of liver1.00infobox
SCP2Bgeepalpebral conjunctiva1.00infobox
SCP2Bgeegerminal epithelium1.00infobox
SCP2Bgeeduodenum1.00infobox
SCP2Bgeerectum1.00infobox
SCP2Bgeeepithelium of nasopharynx1.00infobox
SCP2Bgeemucosa of sigmoid colon1.00infobox
SCP2Bgeegallbladder1.00infobox
SCP2Bgeepylorus1.00infobox
SCP2Bgeeproximal tubule1.00infobox
SCP2Bgeeright kidney1.00infobox
SCP2Bgeewhite adipose tissue1.00infobox
SCP2Bgeehepatobiliary system1.00infobox
SCP2Bgeeliver1.00infobox
SCP2Bgeejejunum1.00infobox
SCP2Bgeegranulocyte1.00infobox
SCP2Bgeehuman kidney1.00infobox
SCP2Bgeecolon1.00infobox
SCP2BioGPSn/a1.00infobox
SCP2Chr.Chromosome 1 (human)1.00infobox
SCP2Chr.Chromosome 4 (mouse)1.00infobox
SCP2DatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around SCP2 bring nearby vocabulary together. In this analysis, examples include Scpx, Sterol and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SCP2
    • Scpx
    • Sterol
    • Activity
    • Encodes
    • Fatty
    • Function
    • Intracellular
    • Peroxisomal
    • Proximal
    • Receptor
    • Search
    • Transfer
  • scp2
    • Scpx
    • Sterol
    • Activity
    • Encodes
    • Fatty
    • Function
    • Intracellular
    • Peroxisomal
    • Proximal
    • Receptor
    • Search
    • Transfer
  • protein
    • Scp2
    • Scpx
    • Carrier
    • Sterol
    • Activity
    • C-acyltransferase
    • Encodes
    • Fatty
    • Function
    • Intracellular
    • Propanoyl-coa
    • Proximal
  • gene
    • Location
    • Sterol
    • Chromosome
    • Human
    • Bp
    • Chr
    • Protein
    • Acid
    • Activity
    • Bile
    • C7
    • End
  • bile acid
    • Bile
    • Expressed
    • Metabolism
    • Lipid
    • Activity
    • C-acyltransferase
    • C7
    • Encodes
    • End
    • Fatty
    • Function
    • Gene
  • function
    • Activity
    • Search
    • Location
    • Sterol
    • Chromosome
    • Human
    • Scpx
    • Bp
    • Chr
    • Protein
    • Acid
    • C7
  • branched chain fatty acids
    • Intracellular
    • Transfer
    • Lipid
    • Scpx
    • Protein
    • Encodes
    • Function
    • Metabolism
    • Mouse
    • Peroxisomal
    • Propanoyl-coa
    • Proximal

Connections between topic areas Semantic bridges

For SCP2, one of the stronger structural bridges in this analysis connects SCP2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SCP2 — Function · splits 11 ⟂ 5
SCP2 — Interactions · splits 12 ⟂ 4
SCP2 — Overview · splits 13 ⟂ 3
SCP2 — Clinical significance · splits 13 ⟂ 3

Map overview Semantic statistics

SCP2

Nodes16
Edges15
Triples113
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around SCP2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SCP2 · EN edition · Analysis: TopicsToTalkAbout

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