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RGFP963

RGFP963, or RGFP-963, is a histone deacetylase (HDAC) inhibitor which is used in scientific research. It is a selective class I HDAC inhibitor, including of HDAC1, HDAC2, and HDAC3 (IC50Tooltip half-maximal inhibitory concentration = 1,510 nM, 750 nM, and 96 nM, respectively). The drug also weakly inhibits HDAC10 (IC50 = 6,640–10,000 nM), whereas it…

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3D model (JSmol)
Interactive image
ATC code
None
CAS Number
1396720-98-1
ChEMBL
ChEMBL4748688
ChemSpider
129454969
Drug class
Histone deacetylase inhibitor; HDAC1, HDAC2, and HDAC3 inhibitor; Cognitive enhancer

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Overview

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Map overview Semantic statistics

RGFP963

Nodes25
Edges24
Triples10
Avg. degree1.92
Density0.08
Components1

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RGFP963

Top relations

3D model (JSmol) · 1
RGFP963 → Interactive image
ATC code · 1
RGFP963 → None
CAS Number · 1
RGFP963 → 1396720-98-1
ChEMBL · 1
RGFP963 → ChEMBL4748688
ChemSpider · 1
RGFP963 → 129454969
Drug class · 1
RGFP963 → Histone deacetylase inhibitor; HDAC1, HDAC2, and HDAC3 inhibitor; Cognitive enhancer
Formula · 1
RGFP963 → C21H20N4O
Molar mass · 1
RGFP963 → 344.418 g·mol−1
Other names · 1
RGFP963 → RGFP-963
PubChem CID · 1
RGFP963 → 60198484

Important terminology Word statistics

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Important terminology

rodents inhibitor hdac1 hdac2 hdac3 also drug model histone deacetylase hdac scientific concentration nm inhibition enhances rgfp-963 class selective hdac10

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RGFP9633D model (JSmol)Interactive image1.00infobox
RGFP963ATC codeNone1.00infobox
RGFP963CAS Number1396720-98-11.00infobox
RGFP963ChEMBLChEMBL47486881.00infobox
RGFP963ChemSpider1294549691.00infobox
RGFP963Drug classHistone deacetylase inhibitor; HDAC1, HDAC2, and HDAC3 inhibitor; Cognitive enhancer1.00infobox
RGFP963FormulaC21H20N4O1.00infobox
RGFP963Molar mass344.418 g·mol−11.00infobox
RGFP963Other namesRGFP-9631.00infobox
RGFP963PubChem CID601984841.00infobox

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