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SRD5A2: Standards & Overview

The human gene SRD5A2 encodes the 3-oxo-5α-steroid 4-dehydrogenase 2 enzyme, also known as 5α-reductase type 2 (5αR2), one of three isozymes of 5α-reductase.

Language: English [EN]
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SRD5A2 topic overview

The analysis highlights Standards and Overview as prominent areas in the source structure around SRD5A2.

Related topics
9
Source areas
1
Connected nodes
10
Extracted relationships
106
Concept neighborhoods
11
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.3.1.22
Aliases
SRD5A2, entrez:6716, steroid 5 alpha-reductase 2
Band
2p23.1 · 17|17 E2
Bgee
corpus epididymis · bronchial epithelial cell · right uterine tube · liver · buccal mucosa cell
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SRD5A2 connects Entity context

The extracted context around SRD5A2 shows recurring relationship patterns in the source. For example, SRD5A2 → 3-oxo-5-alpha-steroid 4-dehydrogenase activity, amide binding, androgen biosynthetic process, androgen metabolic process, biphenyl metabolic process, bone development, cell body fiber, cell differentiation, cell-cell signaling, cholestenone 5-alpha-reductase activity, cytoplasm, dibenzo-p-dioxin metabolic process, endoplasmic reticulum, endoplasmic reticulum membrane, female genitalia development, hippocampus development, hypothalamus development, integral component of membrane, intracellular membrane-bounded organelle, lipid metabolism Another extracted example is SRD5A2 → adrenal gland, bronchial epithelial cell, buccal mucosa cell, caput epididymis, corpus epididymis, ejaculatory duct, embryo, epithelium of lens, lamina propria of prostatic urethra, lamina propria of vagina, lateral lobe of prostate, liver, mucosa of paranasal sinus, olfactory epithelium, prostate, proximal tubule, right kidney, right lobe of liver, right uterine tube, seminal vesicula. Use these groups to spot repeated connection types before inspecting the individual relationships.

SRD5A2

Top relations

Gene ontology · 43
SRD5A2 → 3-oxo-5-alpha-steroid 4-dehydrogenase activity, amide binding, androgen biosynthetic process, androgen metabolic process, biphenyl metabolic process, bone development, cell body fiber, cell differentiation, cell-cell signaling, cholestenone 5-alpha-reductase activity, cytoplasm, dibenzo-p-dioxin metabolic process, endoplasmic reticulum, endoplasmic reticulum membrane, female genitalia development, hippocampus development, hypothalamus development, integral component of membrane, intracellular membrane-bounded organelle, lipid metabolism
Bgee · 20
SRD5A2 → adrenal gland, bronchial epithelial cell, buccal mucosa cell, caput epididymis, corpus epididymis, ejaculatory duct, embryo, epithelium of lens, lamina propria of prostatic urethra, lamina propria of vagina, lateral lobe of prostate, liver, mucosa of paranasal sinus, olfactory epithelium, prostate, proximal tubule, right kidney, right lobe of liver, right uterine tube, seminal vesicula
RNA expression pattern · 20
SRD5A2 → adrenal gland, bronchial epithelial cell, buccal mucosa cell, caput epididymis, corpus epididymis, ejaculatory duct, embryo, epithelium of lens, lamina propria of prostatic urethra, lamina propria of vagina, lateral lobe of prostate, liver, mucosa of paranasal sinus, olfactory epithelium, prostate, proximal tubule, right kidney, right lobe of liver, right uterine tube, seminal vesicula
Band · 2
SRD5A2 → 17|17 E2, 2p23.1
Chr. · 2
SRD5A2 → Chromosome 17 (mouse), Chromosome 2 (human)
End · 2
SRD5A2 → 31,580,938 bp, 74,354,911 bp
1.3.1.22 · 1
SRD5A2 → ↗
Aliases · 1
SRD5A2 → SRD5A2, entrez:6716, steroid 5 alpha-reductase 2
BioGPS · 1
SRD5A2 → More reference expression data
Databases · 1
SRD5A2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp 5αr2 chr band gene chromosome 5α-reductase enzyme male activity location known testosterone androgen prostate also entrez mouse 4-dehydrogenase

SRD5A2 relationships Subject–Predicate–Object triples

TTTA extracted 106 structured relationships around SRD5A2. Examples in this analysis include SRD5A2 → 1.3.1.22 → ↗ and SRD5A2 → Aliases → SRD5A2, entrez:6716, steroid 5 alpha-reductase 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SRD5A21.3.1.221.00infobox
SRD5A2AliasesSRD5A2, entrez:6716, steroid 5 alpha-reductase 21.00infobox
SRD5A2Band2p23.11.00infobox
SRD5A2Band17|17 E21.00infobox
SRD5A2Bgeecorpus epididymis1.00infobox
SRD5A2Bgeebronchial epithelial cell1.00infobox
SRD5A2Bgeeright uterine tube1.00infobox
SRD5A2Bgeeliver1.00infobox
SRD5A2Bgeebuccal mucosa cell1.00infobox
SRD5A2Bgeeright lobe of liver1.00infobox
SRD5A2Bgeecaput epididymis1.00infobox
SRD5A2Bgeeprostate1.00infobox
SRD5A2Bgeeseminal vesicula1.00infobox
SRD5A2Bgeemucosa of paranasal sinus1.00infobox
SRD5A2Bgeeadrenal gland1.00infobox
SRD5A2Bgeeolfactory epithelium1.00infobox
SRD5A2Bgeelamina propria of prostatic urethra1.00infobox
SRD5A2Bgeeepithelium of lens1.00infobox
SRD5A2Bgeeright kidney1.00infobox
SRD5A2Bgeelamina propria of vagina1.00infobox
SRD5A2Bgeeproximal tubule1.00infobox
SRD5A2Bgeeembryo1.00infobox
SRD5A2Bgeelateral lobe of prostate1.00infobox
SRD5A2Bgeeejaculatory duct1.00infobox
SRD5A2BioGPSMore reference expression data1.00infobox
SRD5A2Chr.Chromosome 2 (human)1.00infobox
SRD5A2Chr.Chromosome 17 (mouse)1.00infobox
SRD5A2DatabasesNCBI: entry; OMA: entry1.00infobox
SRD5A2End31,580,938 bp1.00infobox
SRD5A2End74,354,911 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SRD5A2 bring nearby vocabulary together. In this analysis, examples include Steroid, Location and Chromosome. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Human
    • Location
    • Srd5a2
    • Chromosome
    • 4-dehydrogenase
    • Also
    • Bp
    • Chr
    • End
    • Entrez
    • Mouse
    • Steroid
  • 5α-reductase
    • Genitalia
    • Known
    • Activity
    • Male
    • Srd5a2
    • 5αr2
    • Gene
    • Encodes
    • Human
    • Also
    • Androgen
    • End
  • testosterone
    • Androgen
    • Hormone
    • Sex
    • Male
    • Dihydrotestosterone
    • 4-dehydrogenase
    • End
    • Entrez
    • Expressed
    • Genitalia
    • Levels
    • Mouse
  • 5α-reductase 2 deficiency
    • Genitalia
    • Known
    • Activity
    • Male
    • Srd5a2
    • 5αr2
    • Gene
    • Encodes
    • Human
    • Also
    • Androgen
    • End
  • androgen
    • Hormone
    • Sex
    • Testosterone
    • Male
    • Dihydrotestosterone
    • End
    • Entrez
    • Expressed
    • Genitalia
    • Levels
    • Mouse
    • Prostate
  • prostate
    • Protein
    • End
    • Entrez
    • Genitalia
    • Mouse
    • Sex
    • Steroid
    • Testosterone
    • Activity
    • Location
    • Srd5a2
    • Band
  • SRD5A2
    • Steroid
    • Location
    • Chromosome
    • Bp
    • Chr
    • End
    • Mouse
    • Protein
    • Testosterone
    • Band
  • srd5a2
    • Steroid
    • Location
    • Chromosome
    • Bp
    • Chr
    • End
    • Mouse
    • Protein
    • Testosterone
    • Band

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the SRD5A2 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

SRD5A2

Nodes11
Edges10
Triples106
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around SRD5A2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SRD5A2 · EN edition · Analysis: TopicsToTalkAbout

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