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RAPGEF2

Rap guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the RAPGEF2 gene.

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Function

5 related topics

Interactions

3 related topics

Overview

3 related topics

Key facts & relationships

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Aliases
RAPGEF2, CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, RA-GEF-1, Rap-GEP, nRap GEP, Rap guanine nucleotide exchange factor 2, RAGEF
Band
4q32.1 · 3|3 E3
Bgee
Brodmann area 23 · middle temporal gyrus · endothelial cell · frontal pole · postcentral gyrus
BioGPS
n/a
Chr.
Chromosome 4 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Interactions

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Map overview Semantic statistics

RAPGEF2

Nodes15
Edges14
Triples144
Avg. degree1.87
Density0.133333
Components1

How this topic connects Entity context

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RAPGEF2

Top relations

Gene ontology · 72
RAPGEF2 → adenylate cyclase-activating adrenergic receptor signaling pathway, apical plasma membrane, beta-1 adrenergic receptor binding, bicellular tight junction, blood vessel development, brain-derived neurotrophic factor receptor signaling pathway, calcium ion binding, cAMP binding, cAMP-mediated signaling, cell differentiation, cell junction, cell-cell junction, cellular response to cAMP, cellular response to cGMP, cellular response to nerve growth factor stimulus, cGMP binding, cytoplasm, cytosol, diacylglycerol binding, endocytic vesicle
Bgee · 20
RAPGEF2 → amygdala, anterior amygdaloid area, Brodmann area 10, Brodmann area 23, Brodmann area 46, endothelial cell, entorhinal cortex, frontal pole, lateral septal nucleus, middle temporal gyrus, olfactory tubercle, orbitofrontal cortex, piriform cortex, postcentral gyrus, primary motor cortex, Region I of hippocampus proper, subdivision of hippocampus, subiculum, temporal lobe, tibia
RNA expression pattern · 20
RAPGEF2 → amygdala, anterior amygdaloid area, Brodmann area 10, Brodmann area 23, Brodmann area 46, endothelial cell, entorhinal cortex, frontal pole, lateral septal nucleus, middle temporal gyrus, olfactory tubercle, orbitofrontal cortex, piriform cortex, postcentral gyrus, primary motor cortex, Region I of hippocampus proper, subdivision of hippocampus, subiculum, temporal lobe, tibia
related to Function · 9
RAPGEF2 → GDP, GEFs, GTP, GTP-bound, GTP/GDP-regulated, GTPases, Guanine, Members, RAS
Band · 2
RAPGEF2 → 3|3 E3, 4q32.1
Chr. · 2
RAPGEF2 → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
RAPGEF2 → 159,360,174 bp, 79,193,824 bp
related to Interactions · 2
RAPGEF2 → RALGDS, RAP1A
Aliases · 1
RAPGEF2 → RAPGEF2, CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, RA-GEF-1, Rap-GEP, nRap GEP, Rap guanine nucleotide exchange factor 2, RAGEF
BioGPS · 1
RAPGEF2 → n/a

Important terminology Word statistics

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Important terminology

bp chr human band gene protein exchange chromosome rap factor guanine nucleotide location function mouse binding 360 174 end 159

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RAPGEF2AliasesRAPGEF2, CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, RA-GEF-1, Rap-GEP, nRap GEP, Rap guanine nucleotide exchange factor 2, RAGEF1.00infobox
RAPGEF2Band4q32.11.00infobox
RAPGEF2Band3|3 E31.00infobox
RAPGEF2BgeeBrodmann area 231.00infobox
RAPGEF2Bgeemiddle temporal gyrus1.00infobox
RAPGEF2Bgeeendothelial cell1.00infobox
RAPGEF2Bgeefrontal pole1.00infobox
RAPGEF2Bgeepostcentral gyrus1.00infobox
RAPGEF2Bgeeorbitofrontal cortex1.00infobox
RAPGEF2Bgeetibia1.00infobox
RAPGEF2BgeeBrodmann area 101.00infobox
RAPGEF2BgeeBrodmann area 461.00infobox
RAPGEF2Bgeeentorhinal cortex1.00infobox
RAPGEF2Bgeeolfactory tubercle1.00infobox
RAPGEF2Bgeesubdivision of hippocampus1.00infobox
RAPGEF2BgeeRegion I of hippocampus proper1.00infobox
RAPGEF2Bgeesubiculum1.00infobox
RAPGEF2Bgeepiriform cortex1.00infobox
RAPGEF2Bgeelateral septal nucleus1.00infobox
RAPGEF2Bgeetemporal lobe1.00infobox
RAPGEF2Bgeeprimary motor cortex1.00infobox
RAPGEF2Bgeeamygdala1.00infobox
RAPGEF2Bgeeanterior amygdaloid area1.00infobox
RAPGEF2BioGPSn/a1.00infobox
RAPGEF2Chr.Chromosome 4 (human)1.00infobox
RAPGEF2Chr.Chromosome 3 (mouse)1.00infobox
RAPGEF2DatabasesNCBI: entry; OMA: entry1.00infobox
RAPGEF2End159,360,174 bp1.00infobox
RAPGEF2End79,193,824 bp1.00infobox
RAPGEF2EnsemblENSG000001097561.00infobox

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