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Procaine

Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain (without the "e" in the original German patent) or Novocaine (with the "e" in the US…

Pharmacology, Synthesis & Overview

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N01BA02 (WHO) C05AD05 (WHO) S01HA05 (WHO)
Bioavailability
N/A
CAS Number
59-46-1 Y
ChEBI
CHEBI:8430 N

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Overview

Pharmacology

Adverse effects

Synthesis

Advanced semantic analysis

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Map overview Semantic statistics

Procaine

Nodes56
Edges55
Triples54
Avg. degree1.96
Density0.035714
Components1

How this topic connects Entity context

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Procaine

Top relations

has effect · 10
Procaine → About, Allergic, Application, Nervousness, North Americans, Other, PABA, Studies, The, This
related to Pharmacodynamics · 7
Procaine → As, Aside, Like, The, Unlike, Vasoconstriction, Xylocaine
is a · 4
Procaine → local anesthetic drug of the amino ester group, occasional additive in illicit street drugs and is presented and sold usually as cocaine or heroin, occasional additive in illicit street drugs and is presented and sold usually as cocaine or heroin.PharmacokineticsProcaine, vasodilator
related to Synthesis · 4
Procaine → Finally, Nitrocaine, Raney, The
3D model (JSmol) · 1
Procaine → Interactive image
AHFS/Drugs.com · 1
Procaine → Monograph
ATC code · 1
Procaine → N01BA02 (WHO) C05AD05 (WHO) S01HA05 (WHO)
Bioavailability · 1
Procaine → N/A
CAS Number · 1
Procaine → 59-46-1 Y
ChEBI · 1
Procaine → CHEBI:8430 N

Important terminology Word statistics

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Important terminology

used anesthetic also name use local commonly ester cocaine effects amylocaine dental anesthetics trade novocain einhorn new discovery synthesized hydrolysis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Procaine3D model (JSmol)Interactive image1.00infobox
ProcaineAHFS/Drugs.comMonograph1.00infobox
ProcaineATC codeN01BA02 (WHO) C05AD05 (WHO) S01HA05 (WHO)1.00infobox
ProcaineBioavailabilityN/A1.00infobox
ProcaineCAS Number59-46-1 Y1.00infobox
ProcaineChEBICHEBI:8430 N1.00infobox
ProcaineChEMBLChEMBL569 Y1.00infobox
ProcaineChemSpider4745 Y1.00infobox
ProcaineCompTox Dashboard (EPA)DTXSID70450211.00infobox
ProcaineDrugBankDB00721 N1.00infobox
ProcaineECHA InfoCard100.000.3881.00infobox
ProcaineElimination half-life40–84 seconds1.00infobox
ProcaineExcretionRenal1.00infobox
ProcaineFormulaC13H20N2O21.00infobox
ProcaineIUPHAR/BPS42911.00infobox
ProcaineKEGGD08422 Y1.00infobox
ProcaineLegal statusAU: S4 (Prescription only)1.00infobox
ProcaineMetabolismHydrolysis by plasma esterases1.00infobox
ProcaineMolar mass236.315 g·mol−11.00infobox
ProcaineNIAID ChemDB0191361.00infobox
ProcainePregnancy categoryAU: B21.00infobox
ProcainePubChem CID49141.00infobox
ProcaineRoutes of administrationParenteral1.00infobox
ProcaineUNII4Z8Y51M4381.00infobox
Procaineis alocal anesthetic drug of the amino ester group0.90text
Procaineis avasodilator0.90text
Procaineis aoccasional additive in illicit street drugs and is presented and sold usually as cocaine or heroin.PharmacokineticsProcaine0.90text
Procaineis aoccasional additive in illicit street drugs and is presented and sold usually as cocaine or heroin0.90text

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