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PPP2R4: Measurement, Interactions & Overview

Serine/threonine-protein phosphatase 2A regulatory subunit B is an enzyme that in humans is encoded by the PPP2R4 gene.

Language: English [EN]
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PPP2R4 topic overview

The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around PPP2R4.

Related topics
6
Source areas
2
Connected nodes
8
Extracted relationships
95
Concept neighborhoods
4
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

5.2.1.8
Aliases
PTPA, PP2A, PR53, PPP2R4, protein phosphatase 2 regulatory subunit 4, protein phosphatase 2 phosphatase activator
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G62, 2HV6, 2HV7, 2IXM, 4LAC, 4NY3
Band
9q34.11 · 2 B|2 21.71 cM
Bgee
Brodmann area 10 · frontal pole · apex of heart · middle frontal gyrus · right frontal lobe
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PPP2R4 connects Entity context

The extracted context around PPP2R4 shows recurring relationship patterns in the source. For example, PPP2R4 → ATP binding, ATPase activity, calcium channel complex, cytoplasm, extracellular exosome, isomerase activity, mitotic spindle organization, negative regulation of phosphoprotein phosphatase activity, negative regulation of protein dephosphorylation, nucleoplasm, nucleotide binding, nucleus, peptidyl-prolyl cis-trans isomerase activity, phosphatase activator activity, positive regulation of apoptotic process, positive regulation of phosphoprotein phosphatase activity, positive regulation of protein dephosphorylation, protein binding, protein heterodimerization activity, protein homodimerization activity Another extracted example is PPP2R4 → amygdala, anterior cingulate cortex, aortic valve, apex of heart, ascending aorta, Brodmann area 10, dentate gyrus of hippocampal formation granule cell, external carotid artery, frontal pole, internal carotid artery, lactiferous gland, left testis, middle frontal gyrus, molar, Paneth cell, paraflocculus of cerebellum, perirhinal cortex, right frontal lobe, right testis, Rostral migratory stream. Use these groups to spot repeated connection types before inspecting the individual relationships.

PPP2R4

Top relations

Gene ontology · 27
PPP2R4 → ATP binding, ATPase activity, calcium channel complex, cytoplasm, extracellular exosome, isomerase activity, mitotic spindle organization, negative regulation of phosphoprotein phosphatase activity, negative regulation of protein dephosphorylation, nucleoplasm, nucleotide binding, nucleus, peptidyl-prolyl cis-trans isomerase activity, phosphatase activator activity, positive regulation of apoptotic process, positive regulation of phosphoprotein phosphatase activity, positive regulation of protein dephosphorylation, protein binding, protein heterodimerization activity, protein homodimerization activity
Bgee · 20
PPP2R4 → amygdala, anterior cingulate cortex, aortic valve, apex of heart, ascending aorta, Brodmann area 10, dentate gyrus of hippocampal formation granule cell, external carotid artery, frontal pole, internal carotid artery, lactiferous gland, left testis, middle frontal gyrus, molar, Paneth cell, paraflocculus of cerebellum, perirhinal cortex, right frontal lobe, right testis, Rostral migratory stream
RNA expression pattern · 20
PPP2R4 → amygdala, anterior cingulate cortex, aortic valve, apex of heart, ascending aorta, Brodmann area 10, dentate gyrus of hippocampal formation granule cell, external carotid artery, frontal pole, internal carotid artery, lactiferous gland, left testis, middle frontal gyrus, molar, Paneth cell, paraflocculus of cerebellum, perirhinal cortex, right frontal lobe, right testis, Rostral migratory stream
related to Interactions · 3
PPP2R4 → CCNG1, Janus, PPP2R3A
Band · 2
PPP2R4 → 2 B|2 21.71 cM, 9q34.11
Chr. · 2
PPP2R4 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
PPP2R4 → 129,148,946 bp, 30,447,806 bp
5.2.1.8 · 1
PPP2R4 → ↗
Aliases · 1
PPP2R4 → PTPA, PP2A, PR53, PPP2R4, protein phosphatase 2 regulatory subunit 4, protein phosphatase 2 phosphatase activator
Available structures · 1
PPP2R4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G62, 2HV6, 2HV7, 2IXM, 4LAC, 4NY3

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene phosphatase 2a regulatory protein bp chr subunit human band chromosome activator location encoded b' different enzyme ptpa mouse negative

PPP2R4 relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around PPP2R4. Examples in this analysis include PPP2R4 → 5.2.1.8 → ↗ and PPP2R4 → Aliases → PTPA, PP2A, PR53, PPP2R4, protein phosphatase 2 regulatory subunit 4, protein phosphatase 2 phosphatase activator. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PPP2R45.2.1.81.00infobox
PPP2R4AliasesPTPA, PP2A, PR53, PPP2R4, protein phosphatase 2 regulatory subunit 4, protein phosphatase 2 phosphatase activator1.00infobox
PPP2R4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G62, 2HV6, 2HV7, 2IXM, 4LAC, 4NY31.00infobox
PPP2R4Band9q34.111.00infobox
PPP2R4Band2 B|2 21.71 cM1.00infobox
PPP2R4BgeeBrodmann area 101.00infobox
PPP2R4Bgeefrontal pole1.00infobox
PPP2R4Bgeeapex of heart1.00infobox
PPP2R4Bgeemiddle frontal gyrus1.00infobox
PPP2R4Bgeeright frontal lobe1.00infobox
PPP2R4Bgeeanterior cingulate cortex1.00infobox
PPP2R4Bgeeright testis1.00infobox
PPP2R4Bgeeleft testis1.00infobox
PPP2R4Bgeeparaflocculus of cerebellum1.00infobox
PPP2R4Bgeeamygdala1.00infobox
PPP2R4Bgeeaortic valve1.00infobox
PPP2R4Bgeeascending aorta1.00infobox
PPP2R4Bgeeinternal carotid artery1.00infobox
PPP2R4Bgeeexternal carotid artery1.00infobox
PPP2R4Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PPP2R4BgeePaneth cell1.00infobox
PPP2R4Bgeeperirhinal cortex1.00infobox
PPP2R4BgeeRostral migratory stream1.00infobox
PPP2R4Bgeemolar1.00infobox
PPP2R4Bgeelactiferous gland1.00infobox
PPP2R4BioGPSMore reference expression data1.00infobox
PPP2R4Chr.Chromosome 9 (human)1.00infobox
PPP2R4Chr.Chromosome 2 (mouse)1.00infobox
PPP2R4DatabasesNCBI: entry; OMA: entry1.00infobox
PPP2R4End129,148,946 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PPP2R4 bring nearby vocabulary together. In this analysis, examples include Activity, External and Ptpa. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Activator
    • Location
    • Phosphatase
    • Ppp2r4
    • Chromosome
    • Human
    • Bp
    • Chr
    • Protein
    • Activity
    • End
    • External
  • PPP2R4
    • Activity
    • External
    • Ptpa
    • Search
    • Activator
    • Gene
    • Location
    • Chromosome
    • Human
    • Subunit
    • Bp
    • Chr
  • ppp2r4
    • Activity
    • External
    • Ptpa
    • Search
    • Activator
    • Gene
    • Location
    • Chromosome
    • Human
    • Subunit
    • Bp
    • Chr
  • enzyme
    • Ppp2r4
    • Humans
    • Serine
    • Subunit
    • Threonine-protein
    • Regulatory
    • Activity
    • Encoded
    • External
    • Gene
    • Phosphatase
    • Ptpa

Connections between topic areas Semantic bridges

For PPP2R4, one of the stronger structural bridges in this analysis connects PPP2R4 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PPP2R4Interactions · splits 4 ⟂ 5
PPP2R4Overview · splits 6 ⟂ 3

Map overview Semantic statistics

PPP2R4

Nodes9
Edges8
Triples95
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around PPP2R4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PPP2R4 · EN edition · Analysis: TopicsToTalkAbout

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