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PLGA

PLGA, PLG, or poly(lactic-co-glycolic) acid (CAS: 26780-50-7 ) is a biodegradable, biocompatible copolymer of lactic and glycolic acid used widely in biomedical devices and tissue-engineering materials approved by the Food and Drug Administration (FDA). PLGA is synthesized by means of ring-opening co-polymerization of two different monomers: glycolide…

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Overview

Synthesis

Copolymer

Degradation mechanism

Biocompatibility

Biodegradability

Clinical and Research Applications

Advanced semantic analysis

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Map overview Semantic statistics

PLGA

Nodes52
Edges51
Triples60
Avg. degree1.96
Density0.038462
Components1

How this topic connects Entity context

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PLGA

Top relations

has application · 22
PLGA → By, Cancer, Dental, Doxorubicin, GBE, GTR, In, It, Lupron Depot, One, PLGA's, Powerbone, Prophylactic, PTFE, Some, Specific, Staphylococcus, Synthetic Barrier Membrane, The, There
related to Biodegradability · 8
PLGA → FDA, For, However, Lupron Depot, The, This, To, When
related to Copolymer · 8
PLGA → Depending, Glycolic, HFIP, Higher, Lactic, PLGAs, The, These
related to Degradation mechanism · 8
PLGA → An, Degradation, In, It, Limited, These, This, Water
related to Biocompatibility · 7
PLGA → CO2, Generally PLGA, H2O, Its, Krebs Cycle, The, These
related to External links · 3
PLGA → Media, Wikimedia Commons, Wiktionary-logo-en-v2
related to Synthesis · 3
PLGA → Common, II, Other

Important terminology Word statistics

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Important terminology

acid degradation used polymer glycolic drug body lactic also applications glycolide lactide delivery copolymer biocompatibility implants monomers typically composition systems

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HFIP.PLGA undergoes hydrolysis in the body to produce the original monomersinstance ofHigher lactide polymers can be dissolved using chlorinated solvents whereas higher glycolide materials will require the use of fluorinated solvents0.80text
PLGAhas applicationSpecific0.60section
PLGAhas applicationPLGA's0.60section
PLGAhas applicationSynthetic Barrier Membrane0.60section
PLGAhas applicationPowerbone0.60section
PLGAhas applicationThis0.60section
PLGAhas applicationPTFE0.60section
PLGAhas applicationThe0.60section
PLGAhas applicationGTR0.60section
PLGAhas applicationGBE0.60section
PLGAhas applicationSome0.60section
PLGAhas applicationIn0.60section

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    Min side: 3
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