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PEX6

Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene. PEX6 is an AAA ATPase that localizes to the peroxisome. PEX6 forms a hexamer with PEX1 and is recruited to the membrane by PEX26.

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Aliases
PEX6, PAF-2, PAF2, PBD4A, PDB4B, PXAAA1, HMLR2, peroxisomal biogenesis factor 6
Band
6p21.1 · 17|17 C
Bgee
right uterine tube · body of pancreas · mucosa of transverse colon · right hemisphere of cerebellum · right lobe of liver
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)
Databases
NCBI: entry; OMA: entry

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Map overview Semantic statistics

PEX6

Nodes20
Edges19
Triples93
Avg. degree1.9
Density0.1
Components1

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PEX6

Top relations

Bgee · 20
PEX6 → anterior pituitary, body of pancreas, brown adipose tissue, ciliary body, external carotid artery, internal carotid artery, left lobe of liver, left ovary, motor neuron, mucosa of transverse colon, Paneth cell, right adrenal gland, right frontal lobe, right hemisphere of cerebellum, right lobe of liver, right ovary, right uterine tube, Rostral migratory stream, transitional epithelium of urinary bladder, vas deferens
RNA expression pattern · 20
PEX6 → anterior pituitary, body of pancreas, brown adipose tissue, ciliary body, external carotid artery, internal carotid artery, left lobe of liver, left ovary, motor neuron, mucosa of transverse colon, Paneth cell, right adrenal gland, right frontal lobe, right hemisphere of cerebellum, right lobe of liver, right ovary, right uterine tube, Rostral migratory stream, transitional epithelium of urinary bladder, vas deferens
Gene ontology · 19
PEX6 → ATP binding, ATPase activity, cell projection, cytoplasm, cytosol, membrane, nucleotide binding, peroxisomal membrane, peroxisome, peroxisome organization, photoreceptor cell cilium, photoreceptor outer segment, protein binding, protein C-terminus binding, protein import into peroxisome matrix, protein import into peroxisome matrix, translocation, protein stabilization, protein targeting to peroxisome, protein-containing complex binding
related to Function · 6
PEX6 → Arabidopsis, From, Human PEX6, PEX1, PEX5, Work
related to Related diseases · 6
PEX6 → Because, Mutations, PEX1, Refsum, These, Zellweger Syndrome
Band · 2
PEX6 → 17|17 C, 6p21.1
Chr. · 2
PEX6 → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
PEX6 → 42,979,181 bp, 47,036,467 bp
is a · 2
PEX6 → AAA ATPase that localizes to the peroxisome, key player in the autophagy of peroxisomes called pexophagy
Aliases · 1
PEX6 → PEX6, PAF-2, PAF2, PBD4A, PDB4B, PXAAA1, HMLR2, peroxisomal biogenesis factor 6

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Important terminology

bp human gene chr peroxisome band chromosome peroxisomal membrane external location pex1 function protein mouse biogenesis factor atpase mutants zellweger

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PEX6AliasesPEX6, PAF-2, PAF2, PBD4A, PDB4B, PXAAA1, HMLR2, peroxisomal biogenesis factor 61.00infobox
PEX6Band6p21.11.00infobox
PEX6Band17|17 C1.00infobox
PEX6Bgeeright uterine tube1.00infobox
PEX6Bgeebody of pancreas1.00infobox
PEX6Bgeemucosa of transverse colon1.00infobox
PEX6Bgeeright hemisphere of cerebellum1.00infobox
PEX6Bgeeright lobe of liver1.00infobox
PEX6Bgeeanterior pituitary1.00infobox
PEX6Bgeeright ovary1.00infobox
PEX6Bgeeleft ovary1.00infobox
PEX6Bgeeright frontal lobe1.00infobox
PEX6Bgeeright adrenal gland1.00infobox
PEX6BgeeRostral migratory stream1.00infobox
PEX6Bgeeinternal carotid artery1.00infobox
PEX6Bgeeleft lobe of liver1.00infobox
PEX6Bgeeexternal carotid artery1.00infobox
PEX6Bgeebrown adipose tissue1.00infobox
PEX6Bgeeciliary body1.00infobox
PEX6Bgeetransitional epithelium of urinary bladder1.00infobox
PEX6Bgeemotor neuron1.00infobox
PEX6BgeePaneth cell1.00infobox
PEX6Bgeevas deferens1.00infobox
PEX6BioGPSMore reference expression data1.00infobox
PEX6Chr.Chromosome 6 (human)1.00infobox
PEX6Chr.Chromosome 17 (mouse)1.00infobox
PEX6DatabasesNCBI: entry; OMA: entry1.00infobox
PEX6End42,979,181 bp1.00infobox
PEX6End47,036,467 bp1.00infobox
PEX6EnsemblENSG000001245871.00infobox

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