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PEX14: Standards, Interactions & Function

Peroxisomal membrane protein PEX14 is a protein that in humans is encoded by the PEX14 gene.

Language: English [EN]
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PEX14 topic overview

The analysis highlights Standards, Interactions and Function as prominent areas in the source structure around PEX14.

Related topics
8
Source areas
3
Connected nodes
11
Extracted relationships
109
Concept neighborhoods
7
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Function · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PEX14, NAPP2, PBD13A, Pex14p, dJ734G22.2, peroxisomal biogenesis factor 14
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2W84, 2W85, 4BXU
Band
1p36.22 · 4|4 E2
Bgee
bronchial epithelial cell · parotid gland · right lobe of liver · pancreatic ductal cell · prefrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PEX14 connects Entity context

The extracted context around PEX14 shows recurring relationship patterns in the source. For example, PEX14 → beta-tubulin binding, fibrillar center, integral component of membrane, intracellular anatomical structure, membrane, microtubule anchoring, microtubule binding, negative regulation of DNA-binding transcription factor activity, negative regulation of protein binding, negative regulation of protein homotetramerization, negative regulation of transcription, DNA-templated, nucleus, peroxisomal importomer complex, peroxisomal membrane, peroxisome, peroxisome organization, peroxisome transport along microtubule, protein binding, protein homooligomerization, protein import into peroxisome matrix Another extracted example is PEX14 → bronchial epithelial cell, CA3 field, choroid plexus of fourth ventricle, endothelial cell, entorhinal cortex, Ileal epithelium, lactiferous gland, muscle of thigh, olfactory zone of nasal mucosa, oocyte, otic placode, otic vesicle, pancreatic ductal cell, parotid gland, perirhinal cortex, prefrontal cortex, right lobe of liver, saccule, urinary bladder, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

PEX14

Top relations

Gene ontology · 32
PEX14 → beta-tubulin binding, fibrillar center, integral component of membrane, intracellular anatomical structure, membrane, microtubule anchoring, microtubule binding, negative regulation of DNA-binding transcription factor activity, negative regulation of protein binding, negative regulation of protein homotetramerization, negative regulation of transcription, DNA-templated, nucleus, peroxisomal importomer complex, peroxisomal membrane, peroxisome, peroxisome organization, peroxisome transport along microtubule, protein binding, protein homooligomerization, protein import into peroxisome matrix
Bgee · 20
PEX14 → bronchial epithelial cell, CA3 field, choroid plexus of fourth ventricle, endothelial cell, entorhinal cortex, Ileal epithelium, lactiferous gland, muscle of thigh, olfactory zone of nasal mucosa, oocyte, otic placode, otic vesicle, pancreatic ductal cell, parotid gland, perirhinal cortex, prefrontal cortex, right lobe of liver, saccule, urinary bladder, yolk sac
RNA expression pattern · 20
PEX14 → bronchial epithelial cell, CA3 field, choroid plexus of fourth ventricle, endothelial cell, entorhinal cortex, Ileal epithelium, lactiferous gland, muscle of thigh, olfactory zone of nasal mucosa, oocyte, otic placode, otic vesicle, pancreatic ductal cell, parotid gland, perirhinal cortex, prefrontal cortex, right lobe of liver, saccule, urinary bladder, yolk sac
related to External links · 11
PEX14 → GeneReviews/NCBI/NIH/UW, Linear Motif, Motif, O75381, PDB, PDBe-KB, Peroxisomal, Peroxisome Biogenesis Disorders, UniProt, Zellweger Syndrome SpectrumEukaryotic Linear, Zellweger Syndrome SpectrumOMIM
Band · 2
PEX14 → 1p36.22, 4|4 E2
Chr. · 2
PEX14 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
PEX14 → 10,630,758 bp, 149,184,333 bp
related to Interactions · 2
PEX14 → PEX5, PEX7
Aliases · 1
PEX14 → PEX14, NAPP2, PBD13A, Pex14p, dJ734G22.2, peroxisomal biogenesis factor 14
Available structures · 1
PEX14 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2W84, 2W85, 4BXU

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene peroxisomal chr human band protein chromosome membrane location peroxisome mouse function external pdb uniprot o75381 factor search 630

PEX14 relationships Subject–Predicate–Object triples

TTTA extracted 109 structured relationships around PEX14. Examples in this analysis include PEX14 → Aliases → PEX14, NAPP2, PBD13A, Pex14p, dJ734G22.2, peroxisomal biogenesis factor 14 and PEX14 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2W84, 2W85, 4BXU. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PEX14AliasesPEX14, NAPP2, PBD13A, Pex14p, dJ734G22.2, peroxisomal biogenesis factor 141.00infobox
PEX14Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2W84, 2W85, 4BXU1.00infobox
PEX14Band1p36.221.00infobox
PEX14Band4|4 E21.00infobox
PEX14Bgeebronchial epithelial cell1.00infobox
PEX14Bgeeparotid gland1.00infobox
PEX14Bgeeright lobe of liver1.00infobox
PEX14Bgeepancreatic ductal cell1.00infobox
PEX14Bgeeprefrontal cortex1.00infobox
PEX14Bgeeurinary bladder1.00infobox
PEX14Bgeemuscle of thigh1.00infobox
PEX14Bgeeolfactory zone of nasal mucosa1.00infobox
PEX14Bgeeendothelial cell1.00infobox
PEX14Bgeeoocyte1.00infobox
PEX14Bgeeotic placode1.00infobox
PEX14Bgeesaccule1.00infobox
PEX14Bgeeotic vesicle1.00infobox
PEX14Bgeeentorhinal cortex1.00infobox
PEX14Bgeeperirhinal cortex1.00infobox
PEX14Bgeechoroid plexus of fourth ventricle1.00infobox
PEX14BgeeCA3 field1.00infobox
PEX14BgeeIleal epithelium1.00infobox
PEX14Bgeelactiferous gland1.00infobox
PEX14Bgeeyolk sac1.00infobox
PEX14BioGPSMore reference expression data1.00infobox
PEX14Chr.Chromosome 1 (human)1.00infobox
PEX14Chr.Chromosome 4 (mouse)1.00infobox
PEX14DatabasesNCBI: entry; OMA: entry1.00infobox
PEX14End10,630,758 bp1.00infobox
PEX14End149,184,333 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PEX14 bring nearby vocabulary together. In this analysis, examples include Protein, Available and Biogenesis. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PEX14
    • Protein
    • Available
    • Biogenesis
    • Entry
    • Factor
    • Function
    • Ncbi
    • O75381
    • Omim
    • Pdb
    • Search
    • Uniprot
  • pex14
    • Protein
    • Available
    • Biogenesis
    • Entry
    • Factor
    • Function
    • Ncbi
    • O75381
    • Omim
    • Pdb
    • Search
    • Uniprot
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Peroxisomal
    • Pex14
    • End
    • Factor
    • Function
    • Mouse
    • Search
  • peroxisomal targeting signal
    • Pex14
    • Protein
    • Peroxisome
    • Gene
    • Available
    • Biogenesis
    • Entry
    • Factor
    • Function
    • Ncbi
    • O75381
    • Omim
  • function
    • Factor
    • Search
    • Location
    • Chromosome
    • Component
    • Human
    • Import
    • Bp
    • Chr
    • Gene
    • Peroxisomal
    • Pex14
  • zellweger syndrome
    • Syndrome
    • Zellweger
    • Available
    • Biogenesis
    • Entry
    • Ncbi
    • O75381
    • Omim
    • Pdb
    • Uniprot
    • Membrane
    • Peroxisome
  • protein
    • Peroxisome
    • Interacts
    • Ncbi
    • O75381
    • Receptor
    • Targeting
    • Uniprot
    • Search
    • Syndrome
    • Zellweger

Connections between topic areas Semantic bridges

For PEX14, one of the stronger structural bridges in this analysis connects PEX14 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PEX14Interactions · splits 7 ⟂ 5
PEX14Overview · splits 9 ⟂ 3
PEX14Function · splits 9 ⟂ 3

Map overview Semantic statistics

PEX14

Nodes12
Edges11
Triples109
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around PEX14 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PEX14 · EN edition · Analysis: TopicsToTalkAbout

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