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Pemetrexed

Pemetrexed, sold under the brand name Alimta among others, is a chemotherapy medication for the treatment of pleural mesothelioma and non-small cell lung cancer (NSCLC).

Applications, Medical use & Mechanism of action

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Explore the main themes, entities and connections around Pemetrexed. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01BA04 (WHO)
Bioavailability
NA
CAS Number
137281-23-3 N
ChEMBL
ChEMBL225072 Y

Topics to explore

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Overview

Medical use

Drug interaction

Mechanism of action

Advanced semantic analysis

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Map overview Semantic statistics

Pemetrexed

Nodes29
Edges28
Triples60
Avg. degree1.93
Density0.068966
Components1

How this topic connects Entity context

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Pemetrexed

Top relations

related to Drug interaction · 8
Pemetrexed → ABC, As, B12, It, MDR1, MRP-5, Orai3, The
related to Mechanism of action · 7
Pemetrexed → By, DHFR, DNA, GARFT, It, RNA, TS
related to Medical use · 6
Pemetrexed → Drug Administration, FDA, Food, In February, In September, NSCLC
Legal status · 4
Pemetrexed → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Supplementation · 4
Pemetrexed → B12, In, It, Patients
related to External links · 3
Pemetrexed → National Cancer Institute, NCI Drug Dictionary, October
related to Research · 3
Pemetrexed → Activity, NSCLC, Phase III
KEGG · 2
Pemetrexed → as salt: D06503 Y, D07472 Y
3D model (JSmol) · 1
Pemetrexed → Interactive image
AHFS/Drugs.com · 1
Pemetrexed → Monograph

Important terminology Word statistics

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Important terminology

cancer cisplatin mesothelioma treatment lung medication drug acid carboplatin patients non-small cell nsclc use brand administration normal name alimta others

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Pemetrexed3D model (JSmol)Interactive image1.00infobox
PemetrexedAHFS/Drugs.comMonograph1.00infobox
PemetrexedATC codeL01BA04 (WHO)1.00infobox
PemetrexedBioavailabilityNA1.00infobox
PemetrexedCAS Number137281-23-3 N1.00infobox
PemetrexedChEMBLChEMBL225072 Y1.00infobox
PemetrexedChemSpider393879 Y1.00infobox
PemetrexedCompTox Dashboard (EPA)DTXSID20483291.00infobox
PemetrexedDrugBankDB00642 Y1.00infobox
PemetrexedECHA InfoCard100.205.7351.00infobox
PemetrexedElimination half-life3.5 hours1.00infobox
PemetrexedExcretionKidney1.00infobox
PemetrexedFormulaC20H21N5O61.00infobox
PemetrexedKEGGD07472 Y1.00infobox
PemetrexedKEGGas salt: D06503 Y1.00infobox
PemetrexedLegal statusAU: S4 (Prescription only)1.00infobox
PemetrexedLegal statusUK: POM (Prescription only)1.00infobox
PemetrexedLegal statusUS: ℞-only1.00infobox
PemetrexedLegal statusEU: Rx-only1.00infobox
PemetrexedLicense dataUS DailyMed: Pemetrexed1.00infobox
PemetrexedMetabolismNegligible1.00infobox
PemetrexedMolar mass427.417 g·mol−11.00infobox
PemetrexedPregnancy categoryAU: D1.00infobox
PemetrexedProtein binding81%1.00infobox
PemetrexedPubChem CID1354108751.00infobox
PemetrexedRoutes of administrationIntravenous1.00infobox
PemetrexedTrade namesAlimta, Pemfexy, Ciambra, others1.00infobox
PemetrexedUNII04Q9AIZ7NO1.00infobox

Related concept clusters Concept neighborhoods

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