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PDGFC: Function, Interactions & Overview

Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. Platelet-derived growth factors are important in connective tissue growth, survival and function, and consist of disulphide-linked dimers involving two polypeptide chains, PDGF-A and PDGF-B. PDGF-C is a member of the PDGF/VEGF…

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PDGFC topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around PDGFC.

Related topics
18
Source areas
3
Connected nodes
21
Extracted relationships
104
Concept neighborhoods
11
Bridge connections
21

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 13 topics
Overview · 4 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PDGFC, FALLOTEIN, SCDGF, platelet derived growth factor C
Band
4q32.1 · 3|3 E3
Bgee
parotid gland · germinal epithelium · tibia · parietal pleura · periodontal fiber
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PDGFC connects Entity context

The extracted context around PDGFC shows recurring relationship patterns in the source. For example, PDGFC → activation of transmembrane receptor protein tyrosine kinase activity, animal organ morphogenesis, blood coagulation, bone development, cell surface, cellular response to amino acid stimulus, central nervous system development, cytoplasm, cytosol, digestive tract development, embryo development, embryonic organ development, endoplasmic reticulum lumen, extracellular exosome, extracellular region, extracellular space, Golgi membrane, growth factor activity, membrane, multicellular organism development Another extracted example is PDGFC → abdominal wall, calvaria, efferent ductule, gastrula, germinal epithelium, internal carotid artery, kidney tubule, metanephric glomerulus, parietal pleura, parotid gland, periodontal fiber, renal corpuscle, seminal vesicula, skin of hip, stroma of bone marrow, stromal cell of endometrium, tibia, tunica media of zone of aorta, vas deferens, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.

PDGFC

Top relations

Gene ontology · 38
PDGFC → activation of transmembrane receptor protein tyrosine kinase activity, animal organ morphogenesis, blood coagulation, bone development, cell surface, cellular response to amino acid stimulus, central nervous system development, cytoplasm, cytosol, digestive tract development, embryo development, embryonic organ development, endoplasmic reticulum lumen, extracellular exosome, extracellular region, extracellular space, Golgi membrane, growth factor activity, membrane, multicellular organism development
Bgee · 20
PDGFC → abdominal wall, calvaria, efferent ductule, gastrula, germinal epithelium, internal carotid artery, kidney tubule, metanephric glomerulus, parietal pleura, parotid gland, periodontal fiber, renal corpuscle, seminal vesicula, skin of hip, stroma of bone marrow, stromal cell of endometrium, tibia, tunica media of zone of aorta, vas deferens, vestibular sensory epithelium
RNA expression pattern · 20
PDGFC → abdominal wall, calvaria, efferent ductule, gastrula, germinal epithelium, internal carotid artery, kidney tubule, metanephric glomerulus, parietal pleura, parotid gland, periodontal fiber, renal corpuscle, seminal vesicula, skin of hip, stroma of bone marrow, stromal cell of endometrium, tibia, tunica media of zone of aorta, vas deferens, vestibular sensory epithelium
related to Interactions · 5
PDGFC → CLP-associated, CLP26, Notably, PDGF-C, PDGFRA
Band · 2
PDGFC → 3|3 E3, 4q32.1
Chr. · 2
PDGFC → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
PDGFC → 156,971,799 bp, 81,121,347 bp
Aliases · 1
PDGFC → PDGFC, FALLOTEIN, SCDGF, platelet derived growth factor C
BioGPS · 1
PDGFC → More reference expression data
Databases · 1
PDGFC → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

growth gene human pdgf-c factor bp platelet-derived chr band chromosome function mouse pdgf-a location factors protein pdgf-b signaling expression activation

PDGFC relationships Subject–Predicate–Object triples

TTTA extracted 104 structured relationships around PDGFC. Examples in this analysis include PDGFC → Aliases → PDGFC, FALLOTEIN, SCDGF, platelet derived growth factor C and PDGFC → Band → 4q32.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PDGFCAliasesPDGFC, FALLOTEIN, SCDGF, platelet derived growth factor C1.00infobox
PDGFCBand4q32.11.00infobox
PDGFCBand3|3 E31.00infobox
PDGFCBgeeparotid gland1.00infobox
PDGFCBgeegerminal epithelium1.00infobox
PDGFCBgeetibia1.00infobox
PDGFCBgeeparietal pleura1.00infobox
PDGFCBgeeperiodontal fiber1.00infobox
PDGFCBgeeskin of hip1.00infobox
PDGFCBgeekidney tubule1.00infobox
PDGFCBgeemetanephric glomerulus1.00infobox
PDGFCBgeeseminal vesicula1.00infobox
PDGFCBgeestromal cell of endometrium1.00infobox
PDGFCBgeegastrula1.00infobox
PDGFCBgeevas deferens1.00infobox
PDGFCBgeeefferent ductule1.00infobox
PDGFCBgeecalvaria1.00infobox
PDGFCBgeeinternal carotid artery1.00infobox
PDGFCBgeetunica media of zone of aorta1.00infobox
PDGFCBgeerenal corpuscle1.00infobox
PDGFCBgeevestibular sensory epithelium1.00infobox
PDGFCBgeestroma of bone marrow1.00infobox
PDGFCBgeeabdominal wall1.00infobox
PDGFCBioGPSMore reference expression data1.00infobox
PDGFCChr.Chromosome 4 (human)1.00infobox
PDGFCChr.Chromosome 3 (mouse)1.00infobox
PDGFCDatabasesNCBI: entry; OMA: entry1.00infobox
PDGFCEnd156,971,799 bp1.00infobox
PDGFCEnd81,121,347 bp1.00infobox
PDGFCEnsemblENSG000001454311.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PDGFC bring nearby vocabulary together. In this analysis, examples include Gene, Human and Ucsc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Human
    • Pdgfc
    • Location
    • Chromosome
    • Ucsc
    • Bp
    • Chr
    • Protein
    • Growth
    • Band
    • Function
    • Mouse
  • platelet-derived growth factor
    • Factor
    • Growth
    • Activation
    • Encoded
    • Platelet-derived
    • Protein
    • Acid
    • Binding
    • Cub
    • Domain
    • Function
    • Latent
  • function
    • Pdgf-a
    • Growth
    • Location
    • Platelet-derived
    • Bp
    • Chr
    • Chromosome
    • External
    • Binding
    • Gene
    • Human
    • Member
  • PDGFC
    • Gene
    • Human
    • Ucsc
    • Location
    • Chromosome
    • Protein
    • Expression
    • Pathway
    • Function
    • Mouse
    • Platelet-derived
    • Signaling
  • pdgfc
    • Gene
    • Human
    • Ucsc
    • Location
    • Chromosome
    • Protein
    • Expression
    • Pathway
    • Function
    • Mouse
    • Platelet-derived
    • Signaling
  • cub domain
    • Domain
    • N-terminal
    • Binding
    • Factor
    • Latent
    • Pdgf-b
    • Proteolytic
    • Receptor
    • Activation
    • Growth
    • May
    • Pdgf-a
  • pdgf-a
    • Pdgf-b
    • May
    • Binding
    • Cub
    • Domain
    • Latent
    • N-terminal
    • Proteolytic
    • Receptor
    • Tissue
    • Pdgf-c
    • Activation
  • pdgf-b
    • Binding
    • Cub
    • Domain
    • Latent
    • N-terminal
    • Proteolytic
    • Receptor
    • Tissue
    • Activation
    • May
    • Platelet-derived
    • Pdgf-c

Connections between topic areas Semantic bridges

For PDGFC, one of the stronger structural bridges in this analysis connects PDGFC with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PDGFCFunction · splits 8 ⟂ 14
PDGFCOverview · splits 17 ⟂ 5

Map overview Semantic statistics

PDGFC

Nodes22
Edges21
Triples104
Avg. degree1.91
Density0.090909
Components1

Source & methodology

TTTA analyzes the structure around PDGFC to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PDGFC · EN edition · Analysis: TopicsToTalkAbout

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