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OXGR1

OXGR1, i.e., 2-oxoglutarate receptor 1 (also known as GPR99, cysteinyl leukotriene receptor E, i.e., CysLTE, and cysteinyl leukotriene receptor 3, i.e., CysLT3) is a G protein-coupled receptor located on the surface membranes of certain cells. It functions by binding one of its ligands and thereby becoming active in triggering pre-programmed responses in…

History, OXGR1 activating and inhibiting ligands & Functions

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Aliases
OXGR1, GPR80, GPR99, P2RY15, P2Y15, aKGR, oxoglutarate receptor 1
Band
13q32.1 · 14|14 E4
Bgee
islet of Langerhans · Achilles tendon · minor salivary glands · olfactory zone of nasal mucosa · rectum
BioGPS
More reference expression data
Chr.
Chromosome 13 (human) · Chromosome 14 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

History

OXGR1 gene

OXGR1 activating and inhibiting ligands

Expression

Functions

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Map overview Semantic statistics

OXGR1

Nodes101
Edges100
Triples147
Avg. degree1.98
Density0.019802
Components1

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OXGR1

Top relations

related to history · 22
OXGR1 → Classification, Finally, GPR80, GPR80/GPR99, GPR91, GPR99, However, In, International Union, Its, IUPHAR, LTC4, LTD4, LTE4, P2Y, P2Y Receptor Nomenclature, P2Y1, P2Y15, Pharmacology Subcommittee, Shortly
related to Associated with LTE4-induced functions · 21
OXGR1 → Alternaria, American, Another, Control, Csltr1, Cstlr2, Cysltr1, Cysltr2, Dermatophagoides, LTC4, LTD4, LTE4, LTE4's, LTE4-induced OXGR1, LTE4-OXGR1, LTF4, LTs, Studies, The, These
Bgee · 19
OXGR1 → Achilles tendon, appendix, central gray substance of midbrain, extraocular muscle, human kidney, islet of Langerhans, lumbar spinal ganglion, lumbar subsegment of spinal cord, metanephros, minor salivary glands, olfactory zone of nasal mucosa, rectum, renal cortex, right kidney, right uterine tube, skin of abdomen, skin of leg, spermatid, spermatocyte
RNA expression pattern · 19
OXGR1 → Achilles tendon, appendix, central gray substance of midbrain, extraocular muscle, human kidney, islet of Langerhans, lumbar spinal ganglion, lumbar subsegment of spinal cord, metanephros, minor salivary glands, olfactory zone of nasal mucosa, rectum, renal cortex, right kidney, right uterine tube, skin of abdomen, skin of leg, spermatid, spermatocyte
related to Inhibiting ligand · 14
OXGR1 → CysLTR1, CysLTR2, CysTR2, Functions, In, Inhibitors, It, LTC4, LTD4, LTE4, Montelukast, Montelukast's, OXGR1's, While
Gene ontology · 7
OXGR1 → G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, membrane, plasma membrane, signal transducer activity, signal transduction
related to Associated with itaconate-regulated functions · 5
OXGR1 → Ca2, Itaconate, Pseudomonas, The, This
related to Activating ligands · 4
OXGR1 → LTC4, LTD4, LTE4, These
related to OXGR1 gene · 4
OXGR1 → Functions, Gq, The, When
related to Associated with OXGR1 gene defects or deficiencies · 3
OXGR1 → It, OXGR1's, The

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Important terminology

gene cells receptor study itaconate mice lte4 ltc4 ltd4 human α-ketoglutarate protein responses knockout functions nasal cysltr1 bp band also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
OXGR1AliasesOXGR1, GPR80, GPR99, P2RY15, P2Y15, aKGR, oxoglutarate receptor 11.00infobox
OXGR1Band13q32.11.00infobox
OXGR1Band14|14 E41.00infobox
OXGR1Bgeeislet of Langerhans1.00infobox
OXGR1BgeeAchilles tendon1.00infobox
OXGR1Bgeeminor salivary glands1.00infobox
OXGR1Bgeeolfactory zone of nasal mucosa1.00infobox
OXGR1Bgeerectum1.00infobox
OXGR1Bgeehuman kidney1.00infobox
OXGR1Bgeeskin of leg1.00infobox
OXGR1Bgeeappendix1.00infobox
OXGR1Bgeeright uterine tube1.00infobox
OXGR1Bgeeskin of abdomen1.00infobox
OXGR1Bgeeright kidney1.00infobox
OXGR1Bgeelumbar subsegment of spinal cord1.00infobox
OXGR1Bgeespermatocyte1.00infobox
OXGR1Bgeespermatid1.00infobox
OXGR1Bgeerenal cortex1.00infobox
OXGR1Bgeeextraocular muscle1.00infobox
OXGR1Bgeelumbar spinal ganglion1.00infobox
OXGR1Bgeemetanephros1.00infobox
OXGR1Bgeecentral gray substance of midbrain1.00infobox
OXGR1BioGPSMore reference expression data1.00infobox
OXGR1Chr.Chromosome 13 (human)1.00infobox
OXGR1Chr.Chromosome 14 (mouse)1.00infobox
OXGR1DatabasesNCBI: entry; OMA: entry1.00infobox
OXGR1End96,994,730 bp1.00infobox
OXGR1End120,279,847 bp1.00infobox
OXGR1EnsemblENSG000001656211.00infobox
OXGR1Entrez271991.00infobox

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