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Organic anion transporter family: Function, Pharmacology & Homology

Members of the Organic Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the…

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Organic anion transporter family topic overview

The analysis highlights Function, Pharmacology and Homology as prominent areas in the source structure around Organic anion transporter family.

Related topics
30
Source areas
4
Connected nodes
34
Extracted relationships
11
Related term clusters
12
Bridge connections
34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 11 topics
Pharmacology · 8 topics
Homology · 6 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR004156 · PF03137
Available protein structures:
IPR004156 · PF03137
InterPro
IPR004156
PDB
IPR004156 PF03137 (ECOD; PDBsum)
Pfam
PF03137
Symbol
OATP

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Homology

Pharmacology

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Organic anion transporter family connects Entity context

The extracted context around Organic anion transporter family shows recurring relationship patterns in the source. For example, Organic anion transporter family → IPR004156, PF03137 Another extracted example is Organic anion transporter family → IPR004156. Use these groups to spot repeated connection types before inspecting the individual relationships.

Organic anion transporter family

Top relations

AlphaFold · 2
Organic anion transporter family → IPR004156, PF03137
Available protein structures: · 2
Organic anion transporter family → IPR004156, PF03137
InterPro · 1
Organic anion transporter family → IPR004156
PDB · 1
Organic anion transporter family → IPR004156 PF03137 (ECOD; PDBsum)
Pfam · 1
Organic anion transporter family → PF03137
Symbol · 1
Organic anion transporter family → OATP
TCDB · 1
Organic anion transporter family → 2.A.60

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

oatps family transport drugs anion oat membrane oatp1b1 well also organic present cell human proteins oatp animal members anions basolateral

Organic anion transporter family relationships Subject–Predicate–Object triples

TTTA extracted 11 structured relationships around Organic anion transporter family. Examples in this analysis include Organic anion transporter family → AlphaFold → IPR004156 and Organic anion transporter family → AlphaFold → PF03137. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Organic anion transporter familyAlphaFoldIPR0041561.00infobox
Organic anion transporter familyAlphaFoldPF031371.00infobox
Organic anion transporter familyAvailable protein structures:IPR0041561.00infobox
Organic anion transporter familyAvailable protein structures:PF031371.00infobox
Organic anion transporter familyInterProIPR0041561.00infobox
Organic anion transporter familyPDBIPR004156 PF03137 (ECOD; PDBsum)1.00infobox
Organic anion transporter familyPfamPF031371.00infobox
Organic anion transporter familySymbolOATP1.00infobox
Organic anion transporter familyTCDB2.A.601.00infobox
thyroidinstance ofthyroid hormones and quinolones.Organic anion transporting polypeptides carry bile acids as well as bilirubin and numerous hormones0.80text
steroid hormones across the basolateral membraneinstance ofthyroid hormones and quinolones.Organic anion transporting polypeptides carry bile acids as well as bilirubin and numerous hormones0.80text

Related concept clusters Related term clusters

The concept neighborhoods around Organic anion transporter family bring nearby vocabulary together. In this analysis, examples include Organic, Family and Hormones. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Organic anion transporter family
    • Organic
    • Family
    • Hormones
    • Proteins
    • Thyroid
    • Across
    • Anion
    • Anions
    • Members
    • Oatp
    • Oat
    • Membrane
  • organic anion transporter family
    • Oat
    • Organic
    • Family
    • Members
    • Proteins
    • Hormones
    • Thyroid
    • Across
    • Anion
    • Anions
    • Oatp
    • Transporter
  • membrane transport proteins
    • Basolateral
    • Proteins
    • Transport
    • Transporting
    • Drugs
    • Drug
    • Liver
    • Organic
    • Present
    • Also
    • Evolution
    • Function
  • cell membrane
    • Basolateral
    • Membrane
    • Oatp
    • Transporting
    • Liver
    • Transport
    • Organic
    • Present
    • Oatps
    • Function
    • Lipid
    • Members
  • anions
    • Members
    • Proteins
    • Oatp
    • Oat
    • Organic
    • Transport
    • Family
    • Across
    • Evolution
    • Function
    • Hormones
    • Thyroid
  • solute carrier family
    • Oat
    • Members
    • Proteins
    • Anions
    • Transporter
    • Oatp
    • Organic
    • Transport
    • Across
    • Evolution
    • Function
    • Hormones
  • basolateral membrane
    • Transporting
    • Basolateral
    • Membrane
    • Liver
    • Well
    • Organic
    • Present
    • Transport
    • Oatps
    • Hormones
    • Oatp2b1
    • Thyroid
  • organic cation transporters
    • Hormones
    • Proteins
    • Thyroid
    • Oatp
    • Oat
    • Membrane
    • Transport
    • Drugs
    • Evolution
    • Function
    • Transporter
    • Transporting

Connections between topic areas Semantic bridges

For Organic anion transporter family, one of the stronger structural bridges in this analysis connects Organic anion transporter family with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Organic anion transporter family — Function · splits 23 ⟂ 12
Organic anion transporter family — Pharmacology · splits 26 ⟂ 9
Organic anion transporter family — Homology · splits 28 ⟂ 7
Organic anion transporter family — Overview · splits 29 ⟂ 6

Map overview Semantic statistics

Organic anion transporter family

Nodes35
Edges34
Triples11
Avg. degree1.94
Density0.057143
Components1

Source & methodology

TTTA analyzes the structure around Organic anion transporter family to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Pharmacology & Homology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Organic anion transporter family · EN edition · Analysis: TopicsToTalkAbout

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