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NEIL1

Endonuclease VIII-like 1 is an enzyme that in humans is encoded by the NEIL1 gene.

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4.2.99.18
Aliases
NEIL1, FPG1, NEI1, hFPG1, nei like DNA glycosylase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TDH, 4NRV, 5ITY, 5ITQ, 5ITU, 5ITX, 5ITR, 5ITT
Band
15q24.2 · 9|9 B
Bgee
right uterine tube · right hemisphere of cerebellum · right adrenal cortex · right frontal lobe · minor salivary glands
BioGPS
More reference expression data

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Targets

Deficiency in cancer

Memory retention

Stroke prevention

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Map overview Semantic statistics

NEIL1

Nodes35
Edges34
Triples108
Avg. degree1.94
Density0.057143
Components1

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NEIL1

Top relations

Gene ontology · 27
NEIL1 → base-excision repair, catalytic activity, cellular response to DNA damage stimulus, chromosome, class I DNA-(apurinic or apyrimidinic site) endonuclease activity, cytoplasm, cytoskeleton, damaged DNA binding, depyrimidination, DNA binding, DNA N-glycosylase activity, DNA repair, DNA-(apurinic or apyrimidinic site) endonuclease activity, hydrolase activity, hydrolase activity, acting on glycosyl bonds, hydrolase activity, hydrolyzing N-glycosyl compounds, lyase activity, metabolism, microtubule organizing center, negative regulation of nuclease activity
Bgee · 20
NEIL1 → anterior pituitary, brown adipose tissue, canal of the cervix, hand, left adrenal cortex, mesenteric lymph nodes, minor salivary glands, muscle of thigh, otolith organ, proximal tubule, right adrenal cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right lobe of liver, right lobe of thyroid gland, right uterine tube, submandibular gland, thymus, utricle
RNA expression pattern · 20
NEIL1 → anterior pituitary, brown adipose tissue, canal of the cervix, hand, left adrenal cortex, mesenteric lymph nodes, minor salivary glands, muscle of thigh, otolith organ, proximal tubule, right adrenal cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right lobe of liver, right lobe of thyroid gland, right uterine tube, submandibular gland, thymus, utricle
related to Deficiency in cancer · 9
NEIL1 → DNA, HNSCC, MGMT, MLH1, NSCLC, RNA, This, When, While
related to Targets · 6
NEIL1 → Because, DNA, FEN-1, PCNA, ROS-damaged, The
Band · 2
NEIL1 → 15q24.2, 9|9 B
Chr. · 2
NEIL1 → Chromosome 15 (human), Chromosome 9 (mouse)
End · 2
NEIL1 → 57,055,589 bp, 75,357,115 bp
4.2.99.18 · 1
NEIL1 → ↗
Aliases · 1
NEIL1 → NEIL1, FPG1, NEI1, hFPG1, nei like DNA glycosylase 1

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Important terminology

dna repair cancer human bp genes damage chr chromosome band gene 15 also hypermethylated citation needed may deficiency mouse location

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
NEIL14.2.99.181.00infobox
NEIL1AliasesNEIL1, FPG1, NEI1, hFPG1, nei like DNA glycosylase 11.00infobox
NEIL1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TDH, 4NRV, 5ITY, 5ITQ, 5ITU, 5ITX, 5ITR, 5ITT1.00infobox
NEIL1Band15q24.21.00infobox
NEIL1Band9|9 B1.00infobox
NEIL1Bgeeright uterine tube1.00infobox
NEIL1Bgeeright hemisphere of cerebellum1.00infobox
NEIL1Bgeeright adrenal cortex1.00infobox
NEIL1Bgeeright frontal lobe1.00infobox
NEIL1Bgeeminor salivary glands1.00infobox
NEIL1Bgeeleft adrenal cortex1.00infobox
NEIL1Bgeecanal of the cervix1.00infobox
NEIL1Bgeeright lobe of liver1.00infobox
NEIL1Bgeeright lobe of thyroid gland1.00infobox
NEIL1Bgeeanterior pituitary1.00infobox
NEIL1Bgeemesenteric lymph nodes1.00infobox
NEIL1Bgeethymus1.00infobox
NEIL1Bgeesubmandibular gland1.00infobox
NEIL1Bgeeotolith organ1.00infobox
NEIL1Bgeeutricle1.00infobox
NEIL1Bgeebrown adipose tissue1.00infobox
NEIL1Bgeehand1.00infobox
NEIL1Bgeeright kidney1.00infobox
NEIL1Bgeeproximal tubule1.00infobox
NEIL1Bgeemuscle of thigh1.00infobox
NEIL1BioGPSMore reference expression data1.00infobox
NEIL1Chr.Chromosome 15 (human)1.00infobox
NEIL1Chr.Chromosome 9 (mouse)1.00infobox
NEIL1DatabasesNCBI: entry; OMA: entry1.00infobox
NEIL1End75,357,115 bp1.00infobox

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